1. Gene
  2. CFAP58 - cilia and flagella associated protein 58 Gene

CFAP58 - cilia and flagella associated protein 58 Gene

种属: Homo sapiens (human)

同用名: SPGF49; CCDC147; C10orf80; bA127L20.4; bA127L20.5; bA554P13.1

基因 ID: 159686 | 基因类型: protein coding

关于 CFAP58

功能概要

Involved in protein localization to motile cilium; sperm axoneme assembly; and sperm mitochondrial sheath assembly. Located in sperm midpiece. Implicated in spermatogenic failure 49. [provided by Alliance of Genome Resources, Apr 2022]

CFAP58 基因产物(1)

mRNA Protein Name
NM_001008723.2 NP_001008723.1 cilia- and flagella-associated protein 58 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in flagellated sperm motility IMP
IMP: 通过突变表型推断
32791035 GOA
involved in protein localization to motile cilium IMP
IMP: 通过突变表型推断
32791035 GOA
involved in sperm axoneme assembly IMP
IMP: 通过突变表型推断
32791035 GOA
involved in sperm mitochondrial sheath assembly IMP
IMP: 通过突变表型推断
32791035 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in sperm flagellum IDA
IDA: 通过直接分析推断
33314088 GOA
located in sperm midpiece IMP
IMP: 通过突变表型推断
32791035 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

cilia- and flagella-associated protein 58

coiled-coil domain containing 147

coiled-coil domain-containing protein 147

CFAP58 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
CFAP58 Q5T655 BACH2 Homo sapiens Q9BYV9
Validated Y2H
32296183
种属内
CFAP58 Q5T655 BACH2 Homo sapiens Q9BYV9
Y2H Prey Pooling
32296183
种属内
CFAP58 Q5T655 BACH2 Homo sapiens Q9BYV9
Y2H Array
32296183
种属内
CFAP58 Q5T655 KRT27 Homo sapiens Q7Z3Y8
Validated Y2H
32296183
种属内
CFAP58 Q5T655 KRT27 Homo sapiens Q7Z3Y8
Y2H Array
32296183
种属内
CFAP58 Q5T655 KRT27 Homo sapiens Q7Z3Y8
Y2H Prey Pooling
32296183
种属内
CFAP58 Q5T655 MCC Homo sapiens P23508
Y2H Array
32296183
种属内
CFAP58 Q5T655 MCC Homo sapiens P23508
Y2H Prey Pooling
32296183
种属内
CFAP58 Q5T655 NAV2 Homo sapiens Q8IVL1
Validated Y2H
25416956
种属内
CFAP58 Q5T655 NAV2 Homo sapiens Q8IVL1
Y2H Prey Pooling
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用