2. Gene
  3. Ajuba - ajuba LIM protein Gene

Ajuba - ajuba LIM protein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Jub

基因 ID: 16475 | 基因类型: protein coding

关于 Ajuba

功能概要

Enables several functions, including actin filament binding activity; alpha-catenin binding activity; and transcription corepressor activity. Acts upstream of or within several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; positive regulation of intracellular signal transduction; and regulation of cellular biosynthetic process. Located in several cellular components, including cytosol; focal adhesion; and lamellipodium. Part of transcription regulator complex. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; sensory organ; and tooth. Orthologous to human AJUBA (ajuba LIM protein). [provided by Alliance of Genome Resources, Apr 2022]

Ajuba 基因产物(1)

mRNA Protein Name
NM_010590.5 NP_034720.2 LIM domain-containing protein ajuba
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin filament binding IDA
IDA: 通过直接分析推断
12417594 MGI
enables alpha-catenin binding IDA
IDA: 通过直接分析推断
12417594 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
18347060 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10330178 MGI
enables protein kinase activator activity IMP
IMP: 通过突变表型推断
15870274 MGI
enables transcription corepressor activity IDA
IDA: 通过直接分析推断
17909014 MGI
enables transcription corepressor activity IMP
IMP: 通过突变表型推断
18331720 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules IMP
IMP: 通过突变表型推断
12417594 MGI
acts upstream of or within focal adhesion assembly IMP
IMP: 通过突变表型推断
15728191 MGI
acts upstream of or within glycerophospholipid biosynthetic process IMP
IMP: 通过突变表型推断
15870270 MGI
acts upstream of or within lamellipodium assembly IMP
IMP: 通过突变表型推断
15728191 MGI
acts upstream of or within negative regulation of kinase activity IDA
IDA: 通过直接分析推断
15870270 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
18347060 MGI
acts upstream of or within positive regulation of MAP kinase activity IDA
IDA: 通过直接分析推断
10330178 MGI
involved in positive regulation of canonical NF-kappaB signal transduction IMP
IMP: 通过突变表型推断
15870274 MGI
acts upstream of or within positive regulation of cellular biosynthetic process IMP
IMP: 通过突变表型推断
15870270 MGI
acts upstream of or within positive regulation of kinase activity IDA
IDA: 通过直接分析推断
15870270 MGI
acts upstream of or within protein localization IMP
IMP: 通过突变表型推断
15870270 MGI
acts upstream of or within regulation of GTPase activity IMP
IMP: 通过突变表型推断
15728191 MGI
acts upstream of or within regulation of cell migration IDA
IDA: 通过直接分析推断
15728191 MGI
acts upstream of or within regulation of cell migration IMP
IMP: 通过突变表型推断
15728191 MGI
acts upstream of or within wound healing, spreading of epidermal cells IMP
IMP: 通过突变表型推断
15728191 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
10330178 MGI
located in focal adhesion IDA
IDA: 通过直接分析推断
15728191 MGI
located in lamellipodium IDA
IDA: 通过直接分析推断
15728191 MGI
located in nucleus IDA
IDA: 通过直接分析推断
18331720 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
18347060 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

LIM domain-containing protein ajuba

protein ajuba

Ajuba 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Ajuba Q91XC0 PRMT5 Homo sapiens O14744
Anti Tag CoIP
20133701
种属间
Ajuba Q91XC0 PRMT5 Homo sapiens O14744
Pull Down
20133701
种属间
Ajuba Q91XC0 RARA Homo sapiens P10276
Pull Down
20133701
种属间
Ajuba Q91XC0 RARA Homo sapiens P10276
Anti Tag CoIP
20133701
种属间
Ajuba Q91XC0 RARA Homo sapiens P10276
GMS
20133701
种属间
Ajuba Q91XC0 RXRG Homo sapiens P48443
Anti Tag CoIP
20133701
种属内
Ajuba Q91XC0 Rarg Mus musculus P18911
Anti Tag CoIP
20133701
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00504 AJUBA Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ajuba NCBI NCBI:84962
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