2. Gene
  3. Kpna1 - karyopherin (importin) alpha 1 Gene

Kpna1 - karyopherin (importin) alpha 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: NPI1; Rch2; IPOA5; mSRP1

基因 ID: 16646 | 基因类型: protein coding

关于 Kpna1

功能概要

Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Involved in postsynapse to nucleus signaling pathway. Acts upstream of or within several processes, including NLS-bearing protein import into nucleus; satellite cell activation involved in skeletal muscle regeneration; and skeletal muscle satellite cell proliferation. Is active in glutamatergic synapse and postsynaptic density. Is expressed in several structures, including central nervous system; genitourinary system; gut; integumental system; and sensory organ. Orthologous to human KPNA1 (karyopherin subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Kpna1 基因产物(1)

mRNA Protein Name
NM_008465.5 NP_032491.2 importin subunit alpha-5
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18716025 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within NLS-bearing protein import into nucleus IMP
IMP: 通过突变表型推断
27434733 MGI
involved in postsynapse to nucleus signaling pathway IDA
IDA: 通过直接分析推断
15603742 MGI
acts upstream of or within regulation of apoptotic process IMP
IMP: 通过突变表型推断
27434733 MGI
acts upstream of or within regulation of canonical Wnt signaling pathway IMP
IMP: 通过突变表型推断
27434733 MGI
acts upstream of or within satellite cell activation involved in skeletal muscle regeneration IMP
IMP: 通过突变表型推断
27434733 MGI
acts upstream of or within skeletal muscle satellite cell proliferation IMP
IMP: 通过突变表型推断
27434733 MGI
acts upstream of or within skeletal muscle tissue regeneration IMP
IMP: 通过突变表型推断
27434733 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
15603742 MGI
is active in glutamatergic synapse IEP
IEP: 通过表达模式推断
15603742 MGI
is active in postsynaptic density IDA
IDA: 通过直接分析推断
15603742 MGI
is active in postsynaptic density IEP
IEP: 通过表达模式推断
15603742 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

importin subunit alpha-5

NPI-1

RAG cohort protein 2

SRP1-beta

importin alpha 5

importin alpha-S1

importin subunit alpha-1

karyopherin subunit alpha-1

m-importin-alpha-S1

nucleoprotein interactor 1

Kpna1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Kpna1 Q60960 SF1 Homo sapiens Q15637
Y2H Fragment Pooling
26420826
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07415 KPNA1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kpna1 NCBI NCBI:3836
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