2. Gene
  3. Cd40 - CD40 molecule Gene

Cd40 - CD40 molecule Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Tnfrsf5

基因 ID: 171369 | 基因类型: protein coding

关于 Cd40

功能概要

Enables antigen binding activity and protein domain specific binding activity. Involved in several processes, including cellular response to cytokine stimulus; response to cobalamin; and response to interferon-gamma. Located in several cellular components, including cell surface; neuronal cell body; and varicosity. Used to study several diseases, including Ehrlich tumor carcinoma; artery disease (multiple); colitis; membranous glomerulonephritis; and obesity. Biomarker of asthma; atherosclerosis; and perinatal necrotizing enterocolitis. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease (multiple); end stage renal disease; hyperimmunoglobulin syndrome (multiple); and non-Hodgkin lymphoma (multiple). Orthologous to human CD40 (CD40 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd40 基因产物(1)

mRNA Protein Name
NM_134360.1 NP_599187.1 tumor necrosis factor receptor superfamily member 5 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables antigen binding IDA
IDA: 通过直接分析推断
22355605 RGD
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
25260678 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in B cell activation IMP
IMP: 通过突变表型推断
27692815 RGD
involved in cellular response to erythropoietin IEP
IEP: 通过表达模式推断
21649646 RGD
involved in cellular response to interleukin-1 IEP
IEP: 通过表达模式推断
10403401 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
19271152 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: 通过表达模式推断
10403401 RGD
involved in response to bacterium IEP
IEP: 通过表达模式推断
22355605 RGD
involved in response to cobalamin IEP
IEP: 通过表达模式推断
16716410 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
21840190 RGD
involved in response to peptide IEP
IEP: 通过表达模式推断
19457161 RGD
involved in response to type II interferon IEP
IEP: 通过表达模式推断
10403401 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
15069176 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
16716410 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
25972624 RGD
located in varicosity IDA
IDA: 通过直接分析推断
25972624 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tumor necrosis factor receptor superfamily member 5

CD40 antigen, TNF receptor superfamily member 5

CD40 molecule, TNF receptor superfamily member 5

tumor necrosis factor receptor superfamily, member 5

重组 Cd40 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74295 CD40 Protein, Rat (HEK293, His) A6JXD6/NP_599187.1 (L20-R193) ≥95%
HY-P74296 CD40 Protein, Rat (HEK293, Fc) A6JXD6 (L20-R193) ≥95%

相关产品

Approval
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-P9950 Omalizumab Inhibitor 99.70% 否
Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-B1618 Corticosterone Agonist 99.76% Phase 3
HY-131968 BMS-986202 Inhibitor 99.92% Phase 1
抗体抑制剂 (14)
目录号 产品名 作用方式
纯度 Phase
HY-P99625 Frexalimab Inhibitor 99.00% Phase 3
HY-P99845 Dazodalibep 99.90% Phase 3
HY-P99049 Sotigalimab Agonist 98.90% Phase 2
HY-P99670 Iscalimab Inhibitor 99.64% Phase 2
HY-P99742 Mitazalimab Inhibitor 98.74% Phase 2
HY-P99167 Lucatumumab Inhibitor 98.18% Phase 2
HY-P99015 Dacetuzumab Inhibitor 95.37% Phase 2
HY-P99257 Bleselumab Inhibitor 98.97% Phase 2
HY-P99315 Ruplizumab Inhibitor 99.84% Phase 2
HY-P99701 Letolizumab Inhibitor 95.00% Phase 2
HY-P990726 Abiprubart 99.00% Phase 2
HY-P99821 Ravagalimab Inhibitor 99.31% Phase 2
HY-P99572 Tecaginlimab Inhibitor 99.00% Phase 2
HY-P99325 Toralizumab Inhibitor 99.57% Phase 1
Pre-clinical Phase
生物活性分子 (23)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-122663A BIO8898 Inhibitor 99.88% 否
HY-120323 DRI-C21045 Inhibitor 99.02% 否
HY-110247 TRAF-STOP inhibitor 6877002 Inhibitor 99.67% 否
HY-148980A Polyinosinic acid sodium / 否
HY-154821A DRI-C21041 (DIEA) Inhibitor / 否
HY-153345 Glucocorticoid receptor agonist-1 phosphate(2,6-difluoro) Ala-Ala-Br Agonist 99.67% 否
HY-154822 DRI-C25441 Inhibitor 99.53% 否
HY-122663 (Rac)-BIO8898 Inhibitor 99.81% 否
HY-16668 Tyrphostin A1 Inhibitor 98.96% 否
HY-152121 Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal Agonist 95.21% 否
HY-49382 Fluocinolone acetonide 3-benzylaniline / 否
HY-154821 DRI-C21041 Inhibitor / 否
HY-148980 Polyinosinic acid / 否
HY-125025 SMI 6860766 Inhibitor / 否
HY-143410 Anti-inflammatory agent 16 Inhibitor / 否
HY-148459 ATAC21 / 否
HY-D1124 Mordant brown 1 / 否
HY-P10399 KGYY15 Inhibitor / 否
HY-RS02246 CD40 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS02247 CD40LG Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-120471 AM-0687 Inhibitor / 否
HY-168384 M04 / 否
HY-400878 Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Mal Agonist 99.86% 否
抗体抑制剂 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P99842A Dapirolizumab Inhibitor 99.40% 否
HY-P99663 Inezetamab Inhibitor 99.77% 否
HY-P990083 Tegoprubart 99.20% 否
HY-P99321 Teneliximab Inhibitor ≥99.0% 否
HY-P990111 BMS-986325 (anti-CD40) Inhibitor 96.46% 否
HY-P990133 Anti-Monkey/Human CD40L/CD154 Antibody (5C8) Inhibitor 99.62% 否
HY-P990134 Anti-Mouse CD40L/CD154 Antibody (MR-1) Inhibitor 95.00% 否
HY-P990269 Anti-Mouse CD40L/CD154 (LALA-PG) Antibody (MR-1) Inhibitor / 否
HY-P990270 Anti-Mouse CD40L/CD154 (D265A) Antibody (MR-1) / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cd40 NCBI NCBI:958
Canis familiaris Cd40 NCBI NCBI:403469
Macaca fascicularis Cd40 NCBI NCBI:102118696
Mus musculus Cd40 NCBI NCBI:21939
Leporidae Cd40 NCBI
Macaca mulatta Cd40 NCBI NCBI:707749
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