2. Gene
  3. Cnot7 - CCR4-NOT transcription complex, subunit 7 Gene

Cnot7 - CCR4-NOT transcription complex, subunit 7 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Caf1; Pop2; CAF-1

基因 ID: 18983 | 基因类型: protein coding

关于 Cnot7

功能概要

Enables poly(A)-specific ribonuclease activity. Involved in gene silencing by RNA; positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; and positive regulation of nuclear-transcribed mRNA poly(A) tail shortening. Acts upstream of or within P-body assembly and positive regulation of RNA metabolic process. Located in P-body and nucleus. Part of CCR4-NOT complex. Is expressed in several structures, including alimentary system; brain; early embryo; genitourinary system; and skeleton. Orthologous to human CNOT7 (CCR4-NOT transcription complex subunit 7). [provided by Alliance of Genome Resources, Apr 2022]

Cnot7 基因产物(5)

mRNA Protein Name
NM_001271542.1 NP_001258471.1 CCR4-NOT transcription complex subunit 7 isoform 1
NM_001271543.1 NP_001258472.1 CCR4-NOT transcription complex subunit 7 isoform 2
NM_001361938.1 NP_001348867.1 CCR4-NOT transcription complex subunit 7 isoform 1
NM_001361939.1 NP_001348868.1 CCR4-NOT transcription complex subunit 7 isoform 3
NM_011135.5 NP_035265.1 CCR4-NOT transcription complex subunit 7 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables piRNA binding IDA
IDA: 通过直接分析推断
24787618 MGI
enables poly(A)-specific ribonuclease activity IMP
IMP: 通过突变表型推断
18625844 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9712883 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within P-body assembly IGI
IGI: 通过遗传相互作用推断
18625844 MGI
acts upstream of or within deadenylation-dependent decapping of nuclear-transcribed mRNA IGI
IGI: 通过遗传相互作用推断
18625844 MGI
acts upstream of or within deadenylation-dependent decapping of nuclear-transcribed mRNA IMP
IMP: 通过突变表型推断
18625844 MGI
acts upstream of or within nuclear-transcribed mRNA poly(A) tail shortening IMP
IMP: 通过突变表型推断
18625844 MGI
involved in piRNA-mediated gene silencing by mRNA destabilization IPI
IPI: 通过物理相互作用推断
24787618 MGI
involved in positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IMP
IMP: 通过突变表型推断
19716330 MGI
involved in positive regulation of nuclear-transcribed mRNA poly(A) tail shortening IMP
IMP: 通过突变表型推断
19716330 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
7791755 MGI
involved in regulatory ncRNA-mediated gene silencing IMP
IMP: 通过突变表型推断
19716330 MGI
involved in spermatogenesis EXP
EXP: 通过实验结果推断
24787618 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of CCR4-NOT complex IPI
IPI: 通过物理相互作用推断
7791755 MGI
located in P-body IDA
IDA: 通过直接分析推断
18625844 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
18625844 MGI
located in nucleus IDA
IDA: 通过直接分析推断
18625844 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

CCR4-NOT transcription complex subunit 7

CCR4-associated factor 1

POP2 homolog

catabolite repressor protein (CCR4)-associative factor 1

Cnot7 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Cross Cnot7 Q60809 BTG2 Homo sapiens P78543
Pull Down
9712883
Cross Cnot7 Q60809 BTG2 Homo sapiens P78543
Y2H
9712883
Intra Cnot7 Q60809 Btg4 Mus musculus O70552
Anti Tag CoIP
27065194
Intra Cnot7 Q60809 Cnot6l Mus musculus Q8VEG6
Anti Bait CoIP
21897366
Cross Cnot7 Q60809 CNOT11 Homo sapiens Q9UKZ1
Pull Down
23232451
Cross Cnot7 Q60809 CNOT11 Homo sapiens Q9UKZ1
TAP
23232451
Cross Cnot7 Q60809 EIF4E Homo sapiens P06730
Anti Tag CoIP
27065194
Cross Cnot7 Q60809 BTG1 Homo sapiens P62324
Y2H
9712883
Intra Cnot7 Q60809 Btg2 Mus musculus Q04211
Pull Down
18337750
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02907 CNOT7 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cnot7 NCBI NCBI:29883
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