2. Gene
  3. Ptgfr - prostaglandin F receptor Gene

Ptgfr - prostaglandin F receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：前列腺素 F 受体

种属: Mus musculus

同用名: fp; PGF

基因 ID: 19220 | 基因类型: protein coding

关于 Ptgfr

Chromosome 3: 151,502,139-151,543,267 reverse strand.GRCm39:CM000996.3

This gene has 3 transcripts (splice variants), 195 orthologues, 7 paralogues and is associated with 3 phenotypes. Biased expression in ovary adult (RPKM 14.), heart adult (RPKM 2.7) and 5 other tissues.

功能概要

预测该基因编码的蛋白编码的蛋白可启动前列腺素F受体活性。参与基因表达的正调控和对雌二醇的反应。在细胞凋亡过程和对脂多糖的反应的负调节的上游或内部起作用。预计位于细胞质中。预计在质膜上有活性。在泄殖腔中表达；生殖器结节;颚;和内脏颅骨。与人 PTGFR（前列腺素 F 受体）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable prostaglandin F receptor activity. Involved in positive regulation of gene expression and response to estradiol. Acts upstream of or within negative regulation of apoptotic process and response to lipopolysaccharide. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Is expressed in cloaca; genital tubercle; jaw; and viscerocranium. Orthologous to human PTGFR (prostaglandin F receptor). [provided by Alliance of Genome Resources, Apr 2022]

Ptgfr 基因产物(1)

mRNA Protein Name
NM_008966.3 NP_032992.1 prostaglandin F2-alpha receptor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
12606450 MGI
involved in positive regulation of gene expression IDA
IDA: 通过直接分析推断
21668646 MGI
involved in response to estradiol IDA
IDA: 通过直接分析推断
10684792 MGI
acts upstream of or within response to lipopolysaccharide IMP
IMP: 通过突变表型推断
15834430 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Ptgfr 蛋白结构

7tmA_FP

7tmA_FP: cd15145 (26 - 315)

7tmA_FP

7tmA_FP: cd15145 (27 - 53)

7tmA_FP

7tmA_FP: cd15145 (65 - 91)

7tmA_FP

7tmA_FP: cd15145 (107 - 137)

7tmA_FP

7tmA_FP: cd15145 (149 - 171)

7tmA_FP

7tmA_FP: cd15145 (196 - 225)

7tmA_FP

7tmA_FP: cd15145 (241 - 271)

7tmA_FP

7tmA_FP: cd15145 (282 - 307)

  • 0
  • 100
  • 200
  • 300
  • 366 a.a.
蛋白主名 其他名称

prostaglandin F2-alpha receptor

PGF receptor

PGF2-alpha receptor

prostaglandin F2alpha receptor

prostanoid FP receptor

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11382 PTGFR Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS11383 Ptgfr Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS11384 Ptgfr Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptgfr NCBI NCBI:5737
Macaca fascicularis Ptgfr NCBI NCBI:102139926
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