2. Gene
  3. DCP1B - decapping mRNA 1B Gene

DCP1B - decapping mRNA 1B Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：脱帽 mRNA 1B

种属: Homo sapiens

同用名: DCP1

基因 ID: 196513 | 基因类型: protein coding

关于 DCP1B

Cytogenetic location: 12p13.33 Genomic coordinates (GRCh38): 12:1,941,591-2,004,457 (from NCBI)

This gene has 7 transcripts (splice variants), 1 gene allele, 212 orthologues and 1 paralogue. Broad expression in testis (RPKM 7.9), endometrium (RPKM 5.4) and 25 other tissues.

功能概要

该基因编码一个蛋白质家族的成员，该蛋白质家族的功能是去除 mRNA 的 5' 帽，这是受调节的 mRNA 衰变的一个步骤。这种蛋白质定位于细胞质灶，这是 mRNA 分解和更新的位点。可变剪接导致多个转录本变体。[RefSeq 提供，2016 年 2 月]

This gene encodes a member of a family of proteins that function in removing the 5' cap from mRNAs, which is a step in regulated mRNA decay. This protein localizes to cytoplasmic foci which are the site of mRNA breakdown and turnover. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

DCP1B 基因产物(2)

mRNA Protein Name
NM_001319292.2 NP_001306221.1 mRNA-decapping enzyme 1B isoform 2
NM_152640.5 NP_689853.3 mRNA-decapping enzyme 1B isoform 1

DCP1B 蛋白结构

DCP1

DCP1: Dcp1-like decapping family (13 - 130)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 617 a.a.
蛋白主名 其他名称

mRNA-decapping enzyme 1B

DCP1 decapping enzyme homolog B

DCP1B 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
DCP1B Q8IZD4 NSMAF Homo sapiens Q92636
Y2H
26133670
种属内
DCP1B Q8IZD4 BAG4 Homo sapiens O95429
Lumier
25036637
种属内
DCP1B Q8IZD4 DCP1A Homo sapiens Q9NPI6
Anti Tag CoIP
16364915
种属内
DCP1B Q8IZD4 DCP1A Homo sapiens Q9NPI6
Anti Tag CoIP
35271311
种属内
DCP1B Q8IZD4 DCP1A Homo sapiens Q9NPI6
Anti Tag CoIP
25036637
种属内
DCP1B Q8IZD4 DCP2 Homo sapiens Q8IU60
Anti Tag CoIP
16364915
种属内
DCP1B Q8IZD4 EDC3 Homo sapiens Q96F86
Anti Tag CoIP
16364915
种属内
DCP1B Q8IZD4 EDC3 Homo sapiens Q96F86
Y2H Array
29892012
种属内
DCP1B Q8IZD4 EDC3 Homo sapiens Q96F86
BN-PAGE
26184334
种属内
DCP1B Q8IZD4 EDC3 Homo sapiens Q96F86
Anti Tag CoIP
35271311
种属内
DCP1B Q8IZD4 EDC3 Homo sapiens Q96F86
Anti Tag CoIP
25036637
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip/Palate Syndrome 3

Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip-Palate Syndrome 3

EEC3

Eec Syndrome 3

Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip/Palate Syndrome, Type 3
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03585 DCP1B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris DCP1B VGNC VGNC:39809
Rattus norvegicus DCP1B RGD RGD:1562214
Macaca mulatta DCP1B VGNC VGNC:71699
Felis catus DCP1B VGNC VGNC:61373
Bos taurus DCP1B VGNC VGNC:27920
Mus musculus DCP1B MGD MGI:2442404
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