2. Gene
  3. Sfrp2 - secreted frizzled-related protein 2 Gene

Sfrp2 - secreted frizzled-related protein 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Sdf5

基因 ID: 20319 | 基因类型: protein coding

关于 Sfrp2

功能概要

Enables Wnt-protein binding activity; endopeptidase activator activity; and receptor ligand activity. Involved in several processes, including regulation of gene expression; regulation of protein phosphorylation; and regulation of signal transduction. Acts upstream of or within several processes, including animal organ development; negative regulation of signal transduction; and regulation of endopeptidase activity. Located in extracellular space. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; eye; and genitourinary system. Orthologous to human SFRP2 (secreted Frizzled related protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Sfrp2 基因产物(1)

mRNA Protein Name
NM_009144.2 NP_033170.1 secreted frizzled-related protein 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables Wnt-protein binding IPI
IPI: 通过物理相互作用推断
17462603 MGI
enables endopeptidase activator activity IDA
IDA: 通过直接分析推断
19079247 MGI
enables enzyme activator activity IDA
IDA: 通过直接分析推断
19079247 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9096311 MGI
enables receptor ligand activity IDA
IDA: 通过直接分析推断
20723538 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of BMP signaling pathway IGI
IGI: 通过遗传相互作用推断
19850029 MGI
acts upstream of or within Wnt signaling pathway involved in somitogenesis IGI
IGI: 通过遗传相互作用推断
18257070 MGI
acts upstream of or within anterior/posterior pattern specification IGI
IGI: 通过遗传相互作用推断
16467359 MGI
acts upstream of or within apoptotic process IMP
IMP: 通过突变表型推断
18729207 MGI
involved in branching involved in blood vessel morphogenesis IDA
IDA: 通过直接分析推断
19458075 MGI
acts upstream of canonical Wnt signaling pathway IGI
IGI: 通过遗传相互作用推断
18257070 MGI
acts upstream of cardiac muscle cell apoptotic process IDA
IDA: 通过直接分析推断
17251350 MGI
acts upstream of or within cartilage development IMP
IMP: 通过突变表型推断
18729207 MGI
involved in cellular response to X-ray IDA
IDA: 通过直接分析推断
19778523 MGI
acts upstream of or within chondrocyte development IMP
IMP: 通过突变表型推断
18729207 MGI
acts upstream of or within collagen fibril organization IMP
IMP: 通过突变表型推断
19079247 MGI
acts upstream of or within convergent extension involved in axis elongation IGI
IGI: 通过遗传相互作用推断
18257070 MGI
acts upstream of or within development of primary male sexual characteristics IGI
IGI: 通过遗传相互作用推断
19100252 MGI
acts upstream of or within digestive tract morphogenesis IGI
IGI: 通过遗传相互作用推断
19300477 MGI
acts upstream of or within embryonic digit morphogenesis IMP
IMP: 通过突变表型推断
18729207 MGI
involved in hematopoietic stem cell proliferation IDA
IDA: 通过直接分析推断
19778523 MGI
acts upstream of or within male gonad development IGI
IGI: 通过遗传相互作用推断
19100252 MGI
acts upstream of mesodermal cell fate specification IGI
IGI: 通过遗传相互作用推断
17462603 MGI
acts upstream of or within negative regulation of BMP signaling pathway IDA
IDA: 通过直接分析推断
19850029 MGI
acts upstream of or within negative regulation of BMP signaling pathway IGI
IGI: 通过遗传相互作用推断
19850029 MGI
acts upstream of or within negative regulation of JUN kinase activity IGI
IGI: 通过遗传相互作用推断
19300477 MGI
involved in negative regulation of Wnt signaling pathway IDA
IDA: 通过直接分析推断
10654605 MGI
acts upstream of or within negative regulation of canonical Wnt signaling pathway IDA
IDA: 通过直接分析推断
17804636 MGI
acts upstream of or within negative regulation of canonical Wnt signaling pathway IGI
IGI: 通过遗传相互作用推断
17462603 MGI
acts upstream of or within negative regulation of cardiac muscle cell apoptotic process IDA
IDA: 通过直接分析推断
17251350 MGI
involved in negative regulation of cell migration IDA
IDA: 通过直接分析推断
10980594 MGI
acts upstream of or within negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IDA
IDA: 通过直接分析推断
17251350 MGI
involved in negative regulation of dermatome development IDA
IDA: 通过直接分析推断
10654605 MGI
involved in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IDA
IDA: 通过直接分析推断
9391078 MGI
involved in negative regulation of gene expression IDA
IDA: 通过直接分析推断
10980594 MGI
acts upstream of or within negative regulation of mesodermal cell fate specification IGI
IGI: 通过遗传相互作用推断
17462603 MGI
involved in negative regulation of peptidyl-tyrosine phosphorylation IDA
IDA: 通过直接分析推断
10980594 MGI
acts upstream of or within neural tube closure IGI
IGI: 通过遗传相互作用推断
19850029 MGI
acts upstream of or within neural tube development IGI
IGI: 通过遗传相互作用推断
19850029 MGI
involved in positive regulation of angiogenesis IDA
IDA: 通过直接分析推断
19458075 MGI
involved in positive regulation of canonical Wnt signaling pathway IDA
IDA: 通过直接分析推断
19001373 MGI
acts upstream of or within positive regulation of canonical Wnt signaling pathway IGI
IGI: 通过遗传相互作用推断
18166153 MGI
involved in positive regulation of cell growth IDA
IDA: 通过直接分析推断
10980594 MGI
involved in positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
10980594 MGI
acts upstream of or within positive regulation of endopeptidase activity IDA
IDA: 通过直接分析推断
19079247 MGI
acts upstream of or within positive regulation of osteoblast differentiation IGI
IGI: 通过遗传相互作用推断
18166153 MGI
involved in positive regulation of peptidyl-serine phosphorylation IDA
IDA: 通过直接分析推断
20723538 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
20723538 MGI
acts upstream of or within post-anal tail morphogenesis IMP
IMP: 通过突变表型推断
18729207 MGI
involved in regulation of Wnt signaling pathway IDA
IDA: 通过直接分析推断
9391078 MGI
acts upstream of or within regulation of apoptotic process IMP
IMP: 通过突变表型推断
18729207 MGI
acts upstream of or within regulation of cell population proliferation IMP
IMP: 通过突变表型推断
18729207 MGI
acts upstream of or within regulation of establishment of planar polarity IGI
IGI: 通过遗传相互作用推断
19300477 MGI
involved in regulation of midbrain dopaminergic neuron differentiation IGI
IGI: 通过遗传相互作用推断
22290867 MGI
involved in regulation of neuron projection development IDA
IDA: 通过直接分析推断
22290867 MGI
involved in regulation of stem cell division IDA
IDA: 通过直接分析推断
19778523 MGI
involved in response to xenobiotic stimulus IDA
IDA: 通过直接分析推断
19778523 MGI
involved in sclerotome development IEP
IEP: 通过表达模式推断
10654605 MGI
acts upstream of or within somitogenesis IGI
IGI: 通过遗传相互作用推断
16467359 MGI
acts upstream of stem cell fate specification IGI
IGI: 通过遗传相互作用推断
17462603 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
9391078 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

secreted frizzled-related protein 2

SARP-1

sFRP-2

secreted apoptosis-related protein 1

secreted frizzled-related sequence protein 2

secreted frizzled-related sequence protein 5

stromal cell derived factor 5

重组 Sfrp2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74553 SFRP2 Protein, Mouse (HEK293, His) NP_033170.1 (L25-C295) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12775 SFRP2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sfrp2 NCBI NCBI:6423
Macaca fascicularis Sfrp2 NCBI NCBI:102147309
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