Slc2a4 - solute carrier family 2 (facilitated glucose transporter), member 4 Gene

中文名称：溶质载体家族 2 (易化葡萄糖转运蛋白) ，成员 4

种属: Mus musculus

同用名: GT2; twgy; Glut4; Glut-4

关于 Slc2a4

功能概要

该基因编码的蛋白可启动葡萄糖跨膜转运蛋白活性。参与细胞对胰岛素刺激的反应。作用于多个过程的上游或内部，包括支链淀粉生物合成过程；棕色脂肪细胞分化；和葡萄糖输入以响应胰岛素刺激。位于几种细胞成分中，包括细胞质囊泡；细胞外外泌体；和肌膜。是质膜的组成部分。以多种结构表达，包括脂肪组织；肾上腺;消化系统；脑;和泌尿生殖系统。用于研究 2 型糖尿病。该基因的人类直系同源物与 2 型糖尿病有关。与人类 SLC2A4（溶质载体家族 2 成员 4）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables glucose transmembrane transporter activity. Involved in cellular response to Insulin stimulus. Acts upstream of or within several processes, including amylopectin biosynthetic process; brown fat cell differentiation; and glucose import in response to Insulin stimulus. Located in several cellular components, including cytoplasmic vesicle; extracellular exosome; and sarcolemma. Is integral component of plasma membrane. Is expressed in several structures, including adipose tissue; adrenal gland; alimentary system; brain; and genitourinary system. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human SLC2A4 (solute carrier family 2 member 4). [provided by Alliance of Genome Resources, Apr 2022]