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  2. Gpr139 - G protein-coupled receptor 139 Gene

Gpr139 - G protein-coupled receptor 139 Gene

中文名称:G 蛋白偶联受体 139

种属: Mus musculus

同用名: PGR3; GPRg1; Gm495

基因 ID: 209776 | 基因类型: protein coding

关于 Gpr139

Chromosome 7: 118,739,970-118,783,826 reverse strand.GRCm39:CM001000.3

This gene has 1 transcript (splice variant), 335 orthologues, 1 paralogue and is associated with 8 phenotypes. Biased expression in whole brain E14.5 (RPKM 4.1), CNS E18 (RPKM 3.7) and 5 other tissues.

功能概要

实现相同的蛋白质结合活性和神经肽受体活性。作用于磷脂酶 C 激活 G 蛋白偶联受体信号通路的上游或内部。预计是质膜的组成部分。以多种结构表达,包括眼睛;回肠;雄性生殖腺或器官;和神经系统。与人类 GPR139(G 蛋白偶联受体 139)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables identical protein binding activity and neuropeptide receptor activity. Acts upstream of or within Phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to be integral component of plasma membrane. Is expressed in several structures, including eye; ileum; male reproductive gland or organ; and nervous system. Orthologous to human GPR139 (G protein-coupled receptor 139). [provided by Alliance of Genome Resources, Apr 2022]

Gpr139 基因产物(1)

mRNA Protein Name
NM_001024138.2 NP_001019309.1 probable G-protein coupled receptor 139
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled receptor activity IDA
IDA: 通过直接分析推断
16378626 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
16378626 MGI
enables neuropeptide receptor activity IDA
IDA: 通过直接分析推断
16378626 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
16378626 MGI
acts upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
16378626 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Gpr139 蛋白结构

7tmA_GPR139

7tmA_GPR139: cd15919 (18 - 287)

7tmA_GPR139

7tmA_GPR139: cd15919 (19 - 45)

7tmA_GPR139

7tmA_GPR139: cd15919 (53 - 78)

7tmA_GPR139

7tmA_GPR139: cd15919 (92 - 122)

7tmA_GPR139

7tmA_GPR139: cd15919 (134 - 154)

7tmA_GPR139

7tmA_GPR139: cd15919 (171 - 196)

7tmA_GPR139

7tmA_GPR139: cd15919 (212 - 244)

7tmA_GPR139

7tmA_GPR139: cd15919 (255 - 280)

  • 0
  • 100
  • 200
  • 300
  • 345 a.a.
蛋白主名 其他名称

probable G-protein coupled receptor 139

G protein-coupled receptor PGR3

g(q)-coupled orphan receptor GPRg1

orphan G protein-coupled receptor TRHRL2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gpr139 NCBI NCBI:124274