2. Gene
  3. CSTF2T - cleavage stimulation factor subunit 2 tau variant Gene

CSTF2T - cleavage stimulation factor subunit 2 tau variant Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：裂解刺激因子亚基 2 tau 变体

种属: Homo sapiens

同用名: CstF-64T

基因 ID: 23283 | 基因类型: protein coding

关于 CSTF2T

Cytogenetic location: 10q21.1 Genomic coordinates (GRCh38): 10:51,695,486-51,699,595 (from NCBI)

This gene has 1 transcript (splice variant), 106 orthologues and 5 paralogues.

功能概要

启用 RNA 结合活性。预计参与聚腺苷酸化所需的 pre-mRNA 切割。位于核质中。 [由基因组资源联盟提供，2022 年 4 月]

Enables RNA binding activity. Predicted to be involved in pre-mRNA cleavage required for polyadenylation. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

CSTF2T 基因产物(1)

mRNA Protein Name
NM_015235.3 NP_056050.1 cleavage stimulation factor subunit 2 tau variant
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CSTF2T 蛋白结构

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (18 - 88)

CSTF2_hinge

CSTF2_hinge: Hinge domain of cleavage stimulation factor subunit 2 (112 - 192)

CSTF_C

CSTF_C: Transcription termination and cleavage factor C-terminal (570 - 613)

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  • 616 a.a.
蛋白主名 其他名称

cleavage stimulation factor subunit 2 tau variant

CF-1 64 kDa subunit tau

CSTF2T 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra CSTF2T Q9H0L4 TLE5 Homo sapiens Q08117-2
Y2H Array
32296183
Intra CSTF2T Q9H0L4 TLE5 Homo sapiens Q08117-2
Y2H Prey Pooling
32296183
Intra CSTF2T Q9H0L4 CTAG1A Homo sapiens P78358
Y2H Array
32296183
Intra CSTF2T Q9H0L4 CTAG1A Homo sapiens P78358
Y2H Prey Pooling
32296183
Intra CSTF2T Q9H0L4 SPAG8 Homo sapiens Q99932-2
Y2H Prey Pooling
32296183
Intra CSTF2T Q9H0L4 SPAG8 Homo sapiens Q99932-2
Y2H Array
32296183
Intra CSTF2T Q9H0L4 FOXI1 Homo sapiens Q12951-2
Y2H Array
32296183
Intra CSTF2T Q9H0L4 FOXI1 Homo sapiens Q12951-2
Y2H Prey Pooling
32296183
Intra CSTF2T Q9H0L4 FAM168B Homo sapiens A1KXE4-2
Y2H Array
32296183
Intra CSTF2T Q9H0L4 FAM168B Homo sapiens A1KXE4-2
Y2H Prey Pooling
32296183
Intra CSTF2T Q9H0L4 ATP23 Homo sapiens Q9Y6H3
Y2H Array
32296183
Intra CSTF2T Q9H0L4 ATP23 Homo sapiens Q9Y6H3
Y2H Prey Pooling
32296183
Intra CSTF2T Q9H0L4 ATP23 Homo sapiens Q9Y6H3
Validated Y2H
32296183
Intra CSTF2T Q9H0L4 TOX2 Homo sapiens Q96NM4-3
Y2H Prey Pooling
32296183
Intra CSTF2T Q9H0L4 TOX2 Homo sapiens Q96NM4-3
Y2H Array
32296183
Intra CSTF2T Q9H0L4 STH Homo sapiens Q8IWL8
Y2H Prey Pooling
32296183
Intra CSTF2T Q9H0L4 STH Homo sapiens Q8IWL8
Y2H Array
32296183
Intra CSTF2T Q9H0L4 a0a1u9x8x8_human Homo sapiens A0A1U9X8X8
Y2H Array
32296183
Intra CSTF2T Q9H0L4 a0a1u9x8x8_human Homo sapiens A0A1U9X8X8
Y2H Prey Pooling
32296183
Intra CSTF2T Q9H0L4 COL17A1 Homo sapiens Q9UMD9
Y2H Array
32296183
Intra CSTF2T Q9H0L4 COL17A1 Homo sapiens Q9UMD9
Validated Y2H
32296183
Intra CSTF2T Q9H0L4 COL17A1 Homo sapiens Q9UMD9
Y2H Prey Pooling
32296183
Intra CSTF2T Q9H0L4 PKNOX2 Homo sapiens Q96KN3
Y2H Prey Pooling
32296183
Intra CSTF2T Q9H0L4 PKNOX2 Homo sapiens Q96KN3
Y2H Array
32296183
Intra CSTF2T Q9H0L4 FOXJ2 Homo sapiens Q9P0K8
Y2H Prey Pooling
32296183
Intra CSTF2T Q9H0L4 FOXJ2 Homo sapiens Q9P0K8
Y2H Array
32296183
Intra CSTF2T Q9H0L4 SMYD3 Homo sapiens Q9H7B4
Y2H Array
32296183
Intra CSTF2T Q9H0L4 SMYD3 Homo sapiens Q9H7B4
Y2H Prey Pooling
32296183
Intra CSTF2T Q9H0L4 SMYD3 Homo sapiens Q9H7B4
Validated Y2H
32296183
Intra CSTF2T Q9H0L4 AKAP8L Homo sapiens Q9ULX6
Y2H Prey Pooling
32296183
Intra CSTF2T Q9H0L4 AKAP8L Homo sapiens Q9ULX6
Validated Y2H
32296183
Intra CSTF2T Q9H0L4 AKAP8L Homo sapiens Q9ULX6
Y2H Array
32296183
Intra CSTF2T Q9H0L4 HGS Homo sapiens O14964
Y2H Prey Pooling
25416956
Intra CSTF2T Q9H0L4 HGS Homo sapiens O14964
Validated Y2H
25416956
Intra CSTF2T Q9H0L4 UBQLN1 Homo sapiens Q9UMX0
Y2H Array
32296183
Intra CSTF2T Q9H0L4 UBQLN1 Homo sapiens Q9UMX0
Y2H Array
25416956
Intra CSTF2T Q9H0L4 UBQLN1 Homo sapiens Q9UMX0
Y2H Pooling
16189514
Intra CSTF2T Q9H0L4 UBQLN1 Homo sapiens Q9UMX0
Validated Y2H
32296183
Intra CSTF2T Q9H0L4 UBQLN1 Homo sapiens Q9UMX0
Y2H Prey Pooling
32296183
Intra CSTF2T Q9H0L4 CTDSP1 Homo sapiens Q9GZU7
Y2H Prey Pooling
32296183
Intra CSTF2T Q9H0L4 CTDSP1 Homo sapiens Q9GZU7
Y2H Array
32296183
Intra CSTF2T Q9H0L4 LASP1 Homo sapiens Q14847-2
Y2H Prey Pooling
32296183
Intra CSTF2T Q9H0L4 LASP1 Homo sapiens Q14847-2
Y2H Array
32296183
Intra CSTF2T Q9H0L4 UBQLN2 Homo sapiens Q9UHD9
Y2H Prey Pooling
32296183
Intra CSTF2T Q9H0L4 UBQLN2 Homo sapiens Q9UHD9
Y2H Array
32296183
Intra CSTF2T Q9H0L4 UBQLN2 Homo sapiens Q9UHD9
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Oligoasthenoteratozoospermia

Oat

Oligoasthenoteratospermia
Oculopharyngeal Muscular Dystrophy

OPMD

Muscular Dystrophy, Oculopharyngeal

Dystrophy, Oculopharyngeal Muscular

Oculopharyngeal Dystrophy

Progressive Muscular Dystrophy, Oculopharyngeal Type

Muscular Dystrophy Oculopharyngeal

Dystrophy, Muscular, Oculopharyngeal
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03275 CSTF2T Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus CSTF2T MGD MGI:1932622
Rattus norvegicus CSTF2T RGD RGD:1310026
Macaca mulatta CSTF2T VGNC VGNC:106027
Bos taurus CSTF2T VGNC VGNC:27782
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