2. Gene
  3. KHNYN - KH and NYN domain containing Gene

KHNYN - KH and NYN domain containing Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：含 KH 和 NYN 域

种属: Homo sapiens

同用名: KIAA0323

基因 ID: 23351 | 基因类型: protein coding

关于 KHNYN

Cytogenetic location: 14q12 Genomic coordinates (GRCh38): 14:24,423,165-24,441,843 (from NCBI)

This gene has 6 transcripts (splice variants), 100 orthologues and 6 paralogues. Ubiquitous expression in stomach (RPKM 18.8), small intestine (RPKM 18.4) and 25 other tissues.

功能概要

该基因编码的蛋白质含有核糖核酸酶 NYN 结构域，属于 N4BP1 家族。该蛋白是锌指抗病毒蛋白 (ZAP 蛋白) 的辅助因子，ZAP 蛋白靶向病毒 RNA 进行降解并限制 SARS-CoV-2 感染。[RefSeq 提供，2021 年 9 月]

The protein encoded by this gene contains a ribonuclease NYN domain and belongs to the N4BP1 family. The protein is a cofactor for the zinc finger Antiviral protein (ZAP protein) which targets viral RNA for degradation and restricts SARS-CoV-2 Infection. [provided by RefSeq, Sep 2021]

KHNYN 基因产物(3)

mRNA Protein Name
NM_001290256.2 NP_001277185.1 protein KHNYN isoform 2
NM_001290257.2 NP_001277186.1 protein KHNYN isoform 1
NM_015299.3 NP_056114.1 protein KHNYN isoform 1

KHNYN 蛋白结构

RNase_Zc3h12a

RNase_Zc3h12a: Zc3h12a-like Ribonuclease NYN domain (437 - 588)

  • 0
  • 200
  • 400
  • 600
  • 678 a.a.
蛋白主名 其他名称

protein KHNYN

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07241 KHNYN Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus KHNYN VGNC VGNC:30544
Rattus norvegicus KHNYN RGD RGD:1565688
Felis catus KHNYN VGNC VGNC:63080
Canis familiaris KHNYN VGNC VGNC:42339
Mus musculus KHNYN MGD MGI:2451333
Macaca mulatta KHNYN VGNC VGNC:73866
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