1. Gene
  2. BACE1 - beta-secretase 1 Gene

BACE1 - beta-secretase 1 Gene

中文名称:β-分泌酶 1

种属: Homo sapiens

同用名: ASP2; BACE; HSPC104

基因 ID: 23621 | 基因类型: protein coding

关于 BACE1

Cytogenetic location: 11q23.3 Genomic coordinates (GRCh38): 11:117,285,698-117,316,256 (from NCBI)

This gene has 18 transcripts (splice variants), 219 orthologues and 9 paralogues. Ubiquitous expression in pancreas (RPKM 33.5), brain (RPKM 30.2) and 24 other tissues.

功能概要

该基因编码天冬氨酸蛋白酶肽酶 A1 家族的一个成员。可变剪接导致多个转录本变体,其中至少一个编码前原蛋白,该前原蛋白经过蛋白水解处理以产生成熟蛋白酶。这种跨膜蛋白酶催化淀粉样蛋白前体蛋白形成淀粉样蛋白 β 肽的第一步。淀粉样蛋白 β 肽是淀粉样蛋白 β 斑块的主要成分,它在人类阿尔茨海默病患者的大脑中积累。[RefSeq 提供,2015 年 11 月]

This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta Peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer's disease patients. [provided by RefSeq, Nov 2015]

BACE1 基因产物(8)

mRNA Protein Name
NM_138971.4 NP_620427.1 beta-secretase 1 isoform C precursor
NM_138973.4 NP_620429.1 beta-secretase 1 isoform D precursor
XM_047426686.1 XP_047282642.1 beta-secretase 1 isoform X1
NM_138972.4 NP_620428.1 beta-secretase 1 isoform B precursor
NM_012104.6 NP_036236.1 beta-secretase 1 isoform A preproprotein
NM_001207049.3 NP_001193978.1 beta-secretase 1 isoform F
NM_001411039.1 NP_001397968.1 beta-secretase 1 isoform G
NM_001207048.3 NP_001193977.1 beta-secretase 1 isoform E
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables amyloid-beta binding IPI
IPI: 通过物理相互作用推断
16407538 GOA
enables aspartic-type endopeptidase activity IDA
IDA: 通过直接分析推断
10531052 GOA
enables endopeptidase activity IDA
IDA: 通过直接分析推断
10677483 GOA
enables enzyme binding IPI
IPI: 通过物理相互作用推断
12586838 GOA
enables peptidase activity IDA
IDA: 通过直接分析推断
8562317 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
10677483 GOA
enables protein serine/threonine kinase binding IPI
IPI: 通过物理相互作用推断
24305806 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in amyloid-beta formation IDA
IDA: 通过直接分析推断
24352696 GOA
involved in amyloid-beta metabolic process IDA
IDA: 通过直接分析推断
10677483 GOA
involved in membrane protein ectodomain proteolysis IDA
IDA: 通过直接分析推断
18353773 GOA
involved in positive regulation of neuron apoptotic process IGI
IGI: 通过遗传相互作用推断
29371969 GOA
involved in protein processing IDA
IDA: 通过直接分析推断
10531052 GOA
involved in proteolysis IDA
IDA: 通过直接分析推断
10531052 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
10531052 GOA
located in cell surface IDA
IDA: 通过直接分析推断
15886016 GOA
located in early endosome IDA
IDA: 通过直接分析推断
15886016 GOA
located in endosome IDA
IDA: 通过直接分析推断
10531052 GOA
located in late endosome IDA
IDA: 通过直接分析推断
16033761 GOA
located in lysosome IDA
IDA: 通过直接分析推断
16033761 GOA
located in multivesicular body IDA
IDA: 通过直接分析推断
24612608 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
12586838 GOA
located in recycling endosome IDA
IDA: 通过直接分析推断
15886016 GOA
located in trans-Golgi network IDA
IDA: 通过直接分析推断
11466313 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

BACE1 蛋白结构

Asp

Asp: Eukaryotic aspartyl protease (75 - 416)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 501 a.a.
蛋白主名 其他名称

beta-secretase 1

APP beta-secretase

asp 2

aspartyl protease 2

beta-site APP cleaving enzyme 1

beta-site APP-cleaving enzyme

beta-site amyloid beta A4 precursor protein-cleaving enzyme

memapsin-2

membrane-associated aspartic protease 2

transmembrane aspartic proteinase Asp2

BACE1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
BACE1 P56817 Clec4g Mus musculus Q8BNX1
Anti Bait CoIP
25957769
种属间
BACE1 P56817 Clec4g Mus musculus Q8BNX1
Anti Tag CoIP
25957769
种属内
BACE1 P56817 KCNC4 Homo sapiens Q03721
Anti Bait CoIP
29507146
种属内
BACE1 P56817 KCNC4 Homo sapiens Q03721
FRAP
29507146
种属内
BACE1 P56817 GGA1 Homo sapiens Q9UJY5
Confocal
15466887
种属内
BACE1 P56817 GGA1 Homo sapiens Q9UJY5
FRET
15466887
种属内
BACE1 P56817 APP Homo sapiens P05067
Cleavage
22801501
种属内
BACE1 P56817 APP Homo sapiens P05067
FRET
30538620
种属内
BACE1 P56817 APP Homo sapiens P05067
Confocal
10677483
种属内
BACE1 P56817 APP Homo sapiens P05067
Protease Assay
10677483
种属内
BACE1 P56817 IAPP Homo sapiens P10997
Aggregation
26840340
种属内
BACE1 P56817 SNX6 Homo sapiens Q9UNH7
Crosslink
20354142
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 BACE1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72840 BACE1 Protein, Human (HEK293) P56817-1/NP_036236.1 (T22-T457) ≥95%
HY-P72842 BACE1 Protein, Human (HEK293, His) NP_036236.1 (T22-T457) ≥95%
HY-P77569 BACE1 Protein, Human (HEK293, Fc) P56817-1 (T22-T457) ≥95%

关联疾病

疾病名称 别名
Down Syndrome

Trisomy 21

Complete Trisomy 21 Syndrome

Down'S Syndrome

Trisomy 21 Syndrome

Down'S Syndrome - Trisomy 21

Downs Syndrome

G Trisomy

47,Xx,+21

47,Xy,+21

Trisomy G

Down Syndrome, Susceptibility To

Chromosome 21 Trisomy

Trisomy 21 Nos

Abnormal Autosomes 21

Inclusion Body Myositis

Ibm

Sporadic Inclusion Body Myositis

Myositis, Inclusion Body

Inflammatory Myopathy

Inflammatory Myopathies

Sibm

Myositis Inclusion Body

Nonaka Myopathy

Inclusion Body Myopathy, Autosomal Recessive

Inclusion Body Myopathy, Autosomal Dominant

Myositis

Inclusion Body Myopathy, Sporadic

Frontotemporal Dementia

Pallidopontonigral Degeneration

Frontotemporal Lobar Degeneration

Semantic Dementia

FTD

Frontotemporal Lobe Dementia

Multiple System Tauopathy With Presenile Dementia

Dementia, Frontotemporal

Frontotemporal Dementia With Parkinsonism

Mstd

Frontotemporal Lobar Degeneration With Tau Inclusions

Ftld With Tau Inclusions

Dementia, Frontotemporal, With Parkinsonism

Fldem

Ftdp17

Disinhibition-Dementia-Parkinsonism-Amyotrophy Complex

Ddpac

Wilhelmsen-Lynch Disease

Wld

Ppnd

Dementia, Frontotemporal, With Or Without Parkinsonism

Semantic Primary Progressive Aphasia

Semantic Variant Ppa

Wilhemsen-Lynch Disease

Frontotemporal Dementia-Amyotrophic Lateral Sclerosis

Frontotemporal Dementia And Parkinsonism Linked To Chromosome 17

Ftd-Als

Ftld

Pick Complex

Pick Disease Of The Brain

Frontotemporal Dementia With Parkinsonism-17

Grn-Related Frontotemporal Dementia

Frontotemporal Dementia With Motor Neuron Disease

Dementia In Fronto-Temporal Lobar Degeneration

Ftd - [Frontotemporal Dementia]

Temple Dementia

Frontal Lobe Dementia

Peripheral Nervous System Disease

Peripheral Neuropathy

Peripheral Nerve Disease

Peripheral Nerve Disorders

Neuropathy, Peripheral

Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation

Pick Disease Of Brain

Pick Disease

Pick Disease Of The Brain

Lobar Atrophy Of Brain

Dementia With Lobar Atrophy And Neuronal Cytoplasmic Inclusions

Pick'S Disease

Behavioral Variant Of Frontotemporal Dementia

Dementia In Pick'S Disease

Lobar Atrophy Of The Brain

Bvftd

Bv-Ftd

PIDB

Picks Disease

Neurosyphilis

Syphilis Of Central Nervous System

Late Syphilis Of Central Nervous System Nos

Late Syphilis Of The Central Nervous System

Gumma Of Central Nervous System

Neurosyphilis Gumma

Neurosyphilitic Gumma

Syphilis Of Central Nervous System Nos

Syphilitic Gumma Of Central Nervous System

Tertiary Central Nervous System Syphilis

Creutzfeldt-Jakob Disease

Variant Creutzfeldt-Jakob Disease

CJD

Bovine Spongiform Encephalopathy

Vcjd

Inherited Creutzfeldt-Jakob Disease

Creutzfeldt-Jakob Disease, Familial

Creutzfeldt Jakob Disease

Creutzfeldt-Jacob Disease

Creutzfeldt Jacob Disease

Sporadic Creutzfeldt-Jakob Disease

Encephalopathy, Bovine Spongiform

Creutzfeldt-Jakob Disease, Variant, Resistance To

Creutzfeldt-Jakob Disease, Variant

Creutzfeldt Jacob Syndrome

Jakob-Creutzfeldt Disease

Subacute Spongiform Encephalopathy

Transmissible Virus Dementia

New Variant Of Cjd

Nv-Cjd

Variant Cjd

Variant Creutzfeldt-Jacob Disease

Sporadic Cjd

Inherited Cjd

Acquired Creutzfeldt-Jakob Disease

Variant Mcj

Encephalopathy Bovine Spongiform

Familial Creutzfeldt-Jakob Disease

Creutzfeldt-Jakob Syndrome

New Variant Creutzfeldt-Jakob Disease

Creutzfeldt-Jakob Disease, Sporadic

Acquired Cjd

Scjd - [Sporadic Creutzfeldt-Jakob Disease]

Idiopathic Creutzfeldt-Jakob Disease

Creutzfeld-Jakob Disease Nos

Vcjd - [Variant Creutzfeldt-Jakob Disease]

Nervous System Disease

Abnormality Of The Nervous System

Nervous System Diseases

Nervous System Disorder

Disease Of Mental Health

Mental Health

Mental Disorders

Polyradiculoneuropathy
Alzheimer Disease 4

AD4

Alzheimer Disease-4

Alzheimer'S Disease 4

Alzheimer Disease, Familial, 4

Alzheimer Disease, Familial4

Alzheimer'S Disease 4, Early Onset

Alzheimer Disease, Type 4

Subjective Cognitive Decline
Amyloidosis

Amyloid Disease

Amyloid

Amyloid Degeneration

Amyloidosis Nos

Amyloid Deposition

Amyloid Infiltration

Idiopathic Amyloidosis

Hyaloid Degeneration

Lardaceous Degeneration

Cerebral Amyloid Angiopathy, App-Related

Hchwad

Amyloidosis, Cerebroarterial, App-Related

Amyloidosis, Hereditary, With Cerebral Hemorrhage, Dutch Variant

Cerebral Amyloid Angiopathy, App-Related, Dutch Variant

Cerebral Amyloid Angiopathy, App-Related, Iowa Variant

Cerebral Amyloid Angiopathy, App-Related, Italian Variant

Cerebral Amyloid Angiopathy, App-Related, Flemish Variant

Cerebral Amyloid Angiopathy, App-Related, Arctic Variant

Cerebral Amyloid Angiopathy, Dutch, Italian, Iowa, Flemish, Arctic Variants

App-Related Cerebral Amyloid Angiopathy

Abetaa21g Amyloidosis

Abeta Amyloidosis, Italian Type

Abeta Amyloidosis, Arctic Type

Abeta Amyloidosis, Iowa Type

Abeta Amyloidosis, Dutch Type

Hchwa-D

Abeta Amyloidosis, Flemish Type

Abetaa21g-Related Amyloidosis

Hchwa, Flemish Type

Hereditary Cerebral Hemorrhage With Amyloidosis, Flemish Type

Abetae22k Amyloidosis

Hchwa, Italian Type

Hereditary Cerebral Hemorrhage With Amyloidosis, Italian Type

Abetae22g Amyloidosis

Hchwa, Arctic Type

Hereditary Cerebral Hemorrhage With Amyloidosis, Arctic Type

Abetad23n Amyloidosis

Hchwa, Iowa Type

Hereditary Cerebral Hemorrhage With Amyloidosis, Iowa Type

Abetal34v Amyloidosis

Abeta Amyloidosis, Piedmont Type

Abetal34v-Related Amyloidosis

Hchwa, Piedmont Type

Hereditary Cerebral Hemorrhage With Amyloidosis, Piedmont Type

Abetae22q Amyloidosis

Hchwa, Dutch Type

Hereditary Cerebral Hemorrhage With Amyloidosis, Dutch Type

CAA-APP

Amyloidosis Cerebroarterial App-Related

Amyloidosis Hereditary With Cerebral Hemorrhage Dutch Variant

Cerebral Amyloid Angiopathy App-Related Arctic Variant

Cerebral Amyloid Angiopathy App-Related Dutch Variant

Cerebral Amyloid Angiopathy App-Related Flemish Variant

Cerebral Amyloid Angiopathy App-Related Iowa Variant

Cerebral Amyloid Angiopathy App-Related Italian Variant

Familial Occipital Calcifications With Hemorrhagic Strokes Leukoencephalopathy Arterial Dysplasia Dementia

Fochs-Ladd

Hereditary Cerebral Amyloid Angiopathy Dutch Type

Hereditary Cerebral Hemorrhage With Amyloidosis Dutch Type

Hereditary Cerebral Hemorrhage With Amyloidosis Italian Type

Cerebral Hemorrhage With Amyloidosis, Hereditary, Dutch Type

Schizophrenia

SCZD

Schizophrenia With Or Without An Affective Disorder

Schizophrenia 12

Schizophrenia, Susceptibility To

Schizophrenia-1

Dementia Praecox

Schizophrenia 1

Amyotrophic Lateral Sclerosis 1

Amyotrophic Lateral Sclerosis

ALS

Lou Gehrig Disease

Amyotrophic Lateral Sclerosis Type 1

Charcot Disease

ALS1

Amyotrophic Lateral Sclerosis, Susceptibility To

Fals

Lou Gehrig'S Disease

Mnd

Motor Neuron Disease

Familial Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis 1, Familial

Amyotrophic Lateral Sclerosis 1, Autosomal Dominant

Motor Neuron Disease, Bulbar

Motor Neurone Disease

Amyotrophic Lateral Sclerosis With Dementia

Dementia With Amyotrophic Lateral Sclerosis

Motor Neuron Disease, Amyotrophic Lateral Sclerosis

Sclerosis, Lateral, Amyotrophic

Sclerosis, Lateral, Amyotrophic, Type 1

Amyotrophic Sclerosis

Als - [Amyotrophic Lateral Sclerosis]

Wasting Palsy

Amyotrophic Paralysis

Amyotrophy Lateral Sclerosis

Wasting Paralysis

Spinal Progressive Amyotrophy

Progressive Atrophic Paralysis

Toxic Encephalopathy

Neurotoxicity

Neurotoxicity Syndromes

Neurotoxicity Syndrome

Encephalopathy, Toxic

Mild Cognitive Impairment
Myositis

Idiopathic Inflammatory Myopathy

Idiopathic Inflammatory Myositis

Iim

Imm

Idiopathic Inflammatory Myopathies

Myopathy, Familial Idiopathic Inflammatory

Inflammatory Disorder Of Muscle

Idiopathic Inflammatory Myopathy, Familial

Inflammatory Myopathy, Idiopathic

Myopathies Idiopathic Inflammatory

Familial Idiopathic Inflammatory Myopathy

Chromosomal Duplication Syndrome
Necatoriasis

Miner'S Anaemia

Negro Cachexia

Dochmiasis

Ground Itch Disease

Brickmaker'S Chlorosis

Coolie Itch Anaemia

Cachexia Aquosa

Dew Itch Anaemia

Brickmaker'S Anaemia

Tunnel Worker'S Anaemia

Egyptian Anaemia

Tunnel Worker'S Disease

Miner'S Cachexia

Greisinger Disease

Tropical Chlorosis

Egyptian Chlorosis

Tunnel Anaemia

Dochmiosis

Necatorosis

African Cachexia

Water Itch Anaemia

Infection Due To Necator Americanus

St Gotthard Disease

Gotthard Tunnel Disease

Normal Pressure Hydrocephalus

Low Pressure Hydrocephalus

Hydrocephalus Normal Pressure

Hydrocephalus, Normal Pressure

Normal Pressure Hydrocephalus Nos

Nph - [Normal Pressure Hydrocephalus]

Normal Pressure Hydrocephaly

Dementia, Lewy Body

Lewy Body Dementia

Lewy Body Disease

Diffuse Lewy Body Disease

Dementia With Lewy Bodies

DLB

Autosomal Dominant Diffuse Lewy Body Disease

Cortical Lewy Body Disease

Dementia, Lewy Body, Susceptibility To

Lewy Body Dementia, Susceptibility To

Senile Dementia Of The Lewy Body Type

Dementia Of The Lewy Body Type

Lbd

Diffuse Lewy Body Disease With Gaze Palsy

Dysphasic Dementia Hereditary

Lewy Body Type Senile Dementia

Lewy Body Variant Of Alzheimer Disease

Lewy Bodies

Lewy Body

Dlbd - [Diffuse Lewy Body Disease]

Clbd - [Cortical Lewy Body Disease]

Dementia

Dementias

Presenile Dementia

Alzheimer Type Dementia

Alzheimer Sclerosis

Alzheimer Disease Dementia

Alzheimer Dementia

Primary Degenerative Alzheimer Type Dementia

End Stage Alzheimer'S Dementia

Alzheimer'S Type Atypical Dementia

Alzheimer Type Presenile Dementia

Early Onset Alzheimer Dementia

Dementia In Alzheimer Disease Type 2

Dementia In Alzheimer Disease With Early Onset

Early Onset Alzheimer Type Dementia, Uncomplicated

Primary Degenerative Alzheimer Type Dementia, Early Onset

Primary Degenerative Alzheimer Type Dementia, Presenile Onset, Uncomplicated

Alzheimer Disease Dementia With Early Onset

Presenile Sclerosis

Presenile Brain Sclerosis

Presenile Alzheimer Brain Sclerosis

Late Onset Alzheimer Dementia

Dementia In Alzheimer Disease Type 1

Dementia In Alzheimer Disease With Late Onset

Primary Degenerative Alzheimer Type Dementia, Late Onset

Sdat - [Senile Dementia, Alzheimer Type]

Alzheimer Disease Dementia With Late Onset

Late Onset Alzheimer Brain Sclerosis

Senile Alzheimer Brain Disease

Senile Alzheimer Brain Sclerosis

Senile Primary Degenerative Alzheimer Type Dementia

Senile Dementia Of The Alzheimer Type

Arteriosclerotic Dementia

Strategic-Infarct Dementia

Post Stroke Dementia

Vascular Cognitive Impairment

Vascular Dementia

Dementia Of The Lewy Body Type

Dementia With Lewy Bodies

Sdlt - [Senile Dementia Of The Lewy Body Type]

Senile Dementia Of The Lewy Body Type

Alcohol-Related Dementia

Alcoholic Dementia Nos

Alcohol-Induced Dementia

Alcoholic Brain Syndrome

Chronic Alcoholic Brain Syndrome

Alcohol Dementia

Late Onset Alcoholic Psychosis

Residual And Late-Onset Alcohol-Induced Psychotic Disorder

Mental And Behavioural Disorders Due To Use Of Sedatives Or Hypnotics, Residual And Late-Onset Psychotic Disorder

Late-Onset Psychoactive Substance-Induced Psychotic Disorder

Inhalant Dementia

Volatile Solvents Dementia

Dementia In Paralysis Agitans

Pdd - [Parkinson Disease Dementia]

Dementia Syndrome Of Parkinson Disease

Dementia In Parkinson Disease

Parkinson Related Dementia

Dementia In Huntington Chorea

Hiv - [Human Immunodeficiency Virus] Dementia

Hiv- [Human Immunodeficiency Virus] Associated Cognitive Motor Complex

Hiv- [Human Immunodeficiency Virus] Associated Dementia Complex

Aids - [Acquired Immunodeficiency Syndrome] Dementia Complex

Aids Related Dementia

Dementia Due To Niacin Deficiency

Vascular Dementia

Dementia, Vascular

Multi Infarct Dementia

Multifocal Dementia

Dementia Vascular

Vascular Dementia, Susceptibility To

Dementia, Multi-Infarct

Multi-Infarct Dementia

Chromosomal Disease

Chromosomal Disorders

Congenital Chromosomal Disease

Parkinson Disease, Late-Onset

Parkinson Disease

Parkinson'S Disease

PD

PARK

Parkinson Disease, Susceptibility To

Late Onset Parkinson'S Disease

Late Onset Parkinson Disease

Paralysis Agitans

Primary Parkinsonism

Idiopathic Parkinson Disease

Parkinson'S

Parkinson Disease, Late-Onset, Susceptibility To

Parkinson Disease, Age Of Onset, Modifier

Lewy Body Parkinson Disease

Idiopathic Parkinson'S Disease

Pd - [Parkinson Disease]

Parkinson Disease Nos

Parkinson, Nos

Primary Parkinson Disease

Neuroblastoma

Nb

Neuroblastoma, Susceptibility To

Neuroblastomas

Central Neuroblastoma

Alzheimer Disease, Familial, 1

Alzheimer Disease

Alzheimer'S Disease

Presenile And Senile Dementia

AD1

Alzheimer Disease, Susceptibility To

Alzheimer Disease, Late-Onset, Susceptibility To

Alzheimer Disease 1, Familial

AD

Familial Alzheimer Disease

Alzheimer Disease, Late-Onset

Alzheimers Dementia

Alzheimer Dementia

Alzheimer Sclerosis

Alzheimer Syndrome

Alzheimer-Type Dementia

Dat

Primary Senile Degenerative Dementia

Sdat

Alzheimer Disease 1

Autosomal Dominant Alzheimer Disease

Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy

Late Onset Alzheimer Disease

Alzheimers Disease

Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy

Late-Onset Alzheimers Disease

Alzheimer'S Disease Pathway Kegg

Dementia Due To Alzheimer'S Disease

Alzheimer Disease Type 1

Alzheimers

Alzheimer Disease 10

Ad10

Alzheimer Disease-10

Alzheimer'S Disease 10

Alzheimer Disease, Familial, 10

Alzheimer Disease Familial 10

Alzheimer'S Disease 10, Early Onset

Cerebral Amyloid Angiopathy, Cst3-Related

Cerebral Amyloid Angiopathy

Hereditary Cerebral Hemorrhage With Amyloidosis

Hchwa

Cerebral Amyloid Angiopathy, Familial

Hereditary Cystatin C Amyloid Angiopathy

Amyloidosis, Cerebroarterial, Icelandic Type

Amyloidosis Vi

Cerebral Hemorrhage, Hereditary, With Amyloidosis

Cst3-Related Cerebral Amyloid Angiopathy

Cerebral Hemorrhage, Hereditary, With Amyloidosis, Icelandic Variant

Hereditary Cerebral Hemorrhage With Amyloidosis, Icelandic Variant

Caa, Familial

Cerebral Amyloid Angiopathy, Genetic

Acys Amyloidosis

Cst3-Related Amyloidosis

Cystatin Amyloidosis

Hchwa, Icelandic Type

Hereditary Cerebral Hemorrhage With Amyloidosis, Icelandic Type

Amyloidosis 6

AMYL6

Acys

Caa

Cerebral Amyloid Angiopathy Cst3-Related

Cerebroarterial Amyloidosis Icelandic Type

Cystatin C Amyloidosis

Hccaa

Hchwai

Hchwa-I

Hereditary Cerebral Hemorrhage With Amyloidosis Icelandic Type

Cerebral Amyloid Angiopathy Familial

Angiopathy, Amyloid, Cerebral, Cst3-Related

Hereditary Cerebral Amyloid Angiopathy, Icelandic Type

Familial Cerebral Amyloid Angiopathy

Cerebral Amyloid Angiopathy, Hereditary

Stroke, Ischemic

Cerebral Infarction

Stroke

Ischemic Stroke

Cerebrovascular Accident

Cerebral Infarction, Susceptibility To

Stroke, Ischemic, Susceptibility To

Cerebral Infarct

Ischemic Stroke, Susceptibility To

Stroke, Susceptibility To

Cva - Cerebral Infarction

ISCHSTR

Ischemic Cerebrovascular Accident

Alzheimer Disease 3

AD3

Alzheimer Disease, Type 3

Alzheimer Disease, Type 3, With Spastic Paraparesis And Unusual Plaques

Alzheimer Disease, Type 3, With Spastic Paraparesis And Apraxia

Alzheimer'S Disease 3

Alzheimer Disease, Familial, 3, With Spastic Paraparesis And Apraxia

Alzheimer Disease 3, Early-Onset

Alzheimer Disease, Familial, 3

Alzheimer Disease, Protection Against, Due To Apoe3-Christchurch

Alzheimer Disease 3, Early Onset

Alzheimer Disease Familial 3

Early-Onset Familial Alzheimer Disease 3

Familial Alzheimer Disease 3

Familial Alzheimer Disease 3 With Spastic Paraparesis And Apraxia

Familial Alzheimer Disease 3 With Spastic Paraparesis And Unusual Plaques

Alzheimer Disease, Familial, 3, With Spastic Paraparesis And Unusual Plaques

Alzheimer Disease, Familial, Type 3

Amnestic Disorder

Amnesia

Amnestic Syndrome

Korsakoff'S Psychosis Or Syndrome

Amnesic Syndrome

Amnestic Disorder In Conditions Classified Elsewhere

Korsakoff Psychosis Or Syndrome, Nonalcoholic

Nonalcoholic Organic Amnesic Syndrome

Organic Amnesic Syndrome

Cerebrovascular Disease

Cerebrovascular Accident

Cerebrovascular Disorder

Cerebrovascular Disorders

Cva

Stroke

Supranuclear Palsy, Progressive, 1

Progressive Supranuclear Palsy

Steele-Richardson-Olszewski Syndrome

Supranuclear Palsy, Progressive

Psp

Progressive Supranuclear Ophthalmoplegia

PSNP1

Familial Progressive Supranuclear Palsy

Richardson'S Syndrome

Psp Syndrome

Progressive Supranuclear Palsy 1

Supranuclear Palsy Progressive

Ophthalmoplegia, Supranuclear, Progressive

Steele-Richardson-Olszewksi Syndrome

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus BACE1 RGD RGD:2191
Felis catus BACE1 VGNC VGNC:69027
Macaca mulatta BACE1 VGNC VGNC:70215
Mus musculus BACE1 MGD MGI:1346542
Bos taurus BACE1 VGNC VGNC:26400
Canis familiaris BACE1 VGNC VGNC:38358
Others BACE1 NCBI