1. Gene
  2. Gstp1 - glutathione S-transferase pi 1 Gene

Gstp1 - glutathione S-transferase pi 1 Gene

种属: Rattus norvegicus

同用名: Gst3; Gstp; GST-P; Gstp2

基因 ID: 24426 | 基因类型: protein coding

关于 Gstp1

功能概要

Enables organic cyclic compound binding activity; protein kinase binding activity; and toxic substance binding activity. Involved in several processes, including cellular response to cell-matrix adhesion; cellular response to epidermal growth factor stimulus; and cellular response to hormone stimulus. Located in cytosol; nucleus; and plasma membrane. Biomarker of cholestasis; pre-malignant neoplasm; prostate carcinoma in situ; prostatic hypertrophy; and urinary bladder Cancer. Human ortholog(s) of this gene implicated in several diseases, including brain disease (multiple); carcinoma (multiple); hematologic Cancer (multiple); reproductive organ Cancer (multiple); and respiratory system disease (multiple). Orthologous to human GSTP1 (Glutathione S-transferase pi 1). [provided by Alliance of Genome Resources, Apr 2022]

Gstp1 基因产物(1)

mRNA Protein Name
NM_012577.2 NP_036709.1 glutathione S-transferase P
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables organic cyclic compound binding IPI
IPI: 通过物理相互作用推断
11018474 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
23741294 RGD
enables toxic substance binding IPI
IPI: 通过物理相互作用推断
11018474 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in animal organ regeneration IEP
IEP: 通过表达模式推断
7499462 RGD
involved in cellular response to cell-matrix adhesion IEP
IEP: 通过表达模式推断
10793289 RGD
involved in cellular response to epidermal growth factor stimulus IEP
IEP: 通过表达模式推断
1908848 RGD
involved in cellular response to glucocorticoid stimulus IEP
IEP: 通过表达模式推断
18349876 RGD
involved in cellular response to insulin stimulus IEP
IEP: 通过表达模式推断
1908848 RGD
involved in negative regulation of protein kinase activity IMP
IMP: 通过突变表型推断
21668448 RGD
involved in negative regulation of smooth muscle cell chemotaxis IMP
IMP: 通过突变表型推断
24321768 RGD
involved in negative regulation of vascular associated smooth muscle cell proliferation IMP
IMP: 通过突变表型推断
24321768 RGD
involved in oligodendrocyte development IEP
IEP: 通过表达模式推断
17681700 RGD
involved in response to L-ascorbic acid IEP
IEP: 通过表达模式推断
9834927 RGD
involved in response to amino acid IEP
IEP: 通过表达模式推断
20013880 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
9505896 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
2206462 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
16317157 RGD
involved in response to toxic substance IEP
IEP: 通过表达模式推断
19790251 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

glutathione S-transferase P

GST 7-7

GST class-pi

Glutathione-S-transferase, placental enzyme pi type

chain 7

glutathione S-transferase, pi 2

重组 Gstp1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72217 GSTP1 Protein, Rat (His) P04906 (P2-Q210) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gstp1 NCBI NCBI:2950