2. Gene
  3. FUT7 - fucosyltransferase 7 Gene

FUT7 - fucosyltransferase 7 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：岩藻糖基转移酶 7

种属: Homo sapiens

同用名: FucT-VII

基因 ID: 2529 | 基因类型: protein coding

关于 FUT7

Cytogenetic location: 9q34.3 Genomic coordinates (GRCh38): 9:137,030,174-137,032,088 (from NCBI)

This gene has 1 transcript (splice variant), 285 orthologues and 7 paralogues. Biased expression in lymph node (RPKM 1.7), spleen (RPKM 1.5) and 12 other tissues.

功能概要

该基因编码的蛋白质是一种高尔基体膜蛋白，参与唾液酸-路易斯 X 抗原的产生。编码的蛋白质可以指导 E-选择素结合唾液酸-Lewis X 部分的合成。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X antigens. The encoded protein can direct the synthesis of the E-selectin-binding sialyl-Lewis X moiety. [provided by RefSeq, Jul 2008]

FUT7 基因产物(1)

mRNA Protein Name
NM_004479.4 NP_004470.1 alpha-(1,3)-fucosyltransferase 7
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity IDA
IDA: 通过直接分析推断
9473504 GOA
enables alpha-(1->3)-fucosyltransferase activity IDA
IDA: 通过直接分析推断
8207002 GOA
enables alpha-(1->3)-fucosyltransferase activity IMP
IMP: 通过突变表型推断
15926890 GOA
enables fucosyltransferase activity IDA
IDA: 通过直接分析推断
9299472 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ceramide metabolic process IDA
IDA: 通过直接分析推断
9299472 GOA
involved in embryo implantation IMP
IMP: 通过突变表型推断
18402946 GOA
involved in positive regulation of cell adhesion IMP
IMP: 通过突变表型推断
10386892 GOA
involved in positive regulation of cell-cell adhesion IMP
IMP: 通过突变表型推断
18553500 GOA
involved in positive regulation of leukocyte adhesion to vascular endothelial cell IMP
IMP: 通过突变表型推断
29138114 GOA
involved in protein glycosylation IDA
IDA: 通过直接分析推断
11404359 GOA
involved in regulation of cell adhesion molecule production IMP
IMP: 通过突变表型推断
8666674 GOA
involved in regulation of cell-cell adhesion IMP
IMP: 通过突变表型推断
10200296 GOA
involved in regulation of insulin receptor signaling pathway IMP
IMP: 通过突变表型推断
17229154 GOA
involved in regulation of leukocyte cell-cell adhesion IMP
IMP: 通过突变表型推断
23192350 GOA
involved in regulation of leukocyte tethering or rolling IMP
IMP: 通过突变表型推断
23192350 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in trans-Golgi network IDA
IDA: 通过直接分析推断
23192350 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

FUT7 蛋白结构

Glyco_transf_10

Glyco_transf_10: Glycosyltransferase family 10 (fucosyltransferase) C-term (36 - 341)

  • 0
  • 100
  • 200
  • 300
  • 342 a.a.
蛋白主名 其他名称

alpha-(1,3)-fucosyltransferase 7

fuc-TVII

关联疾病

疾病名称 别名
Ehrlichiosis

Human Ehrlichiosis

He

Hey
Human Granulocytic Anaplasmosis

Human Granulocytic Ehrlichiosis

Hge

Human Ehrlichial Infection, Human Granulocytic Type

Human Anaplasmosis Due To Anaplasma Phagocytophilum
T-Cell Acute Lymphoblastic Leukemia

T-Cell Leukemia

Acute T Cell Leukemia

Precursor T Lymphoblastic Leukemia

Precursor T-Lymphoblastic Lymphoma/Leukemia

T Acute Lymphoblastic Leukemia

T-Cell Acute Lymphocytic Leukaemia

T-Cell Lymphoblastic Leukemia/Lymphoma

Leukemia T-Cell

Leukemia, T-Cell

Leukemia, Acute, Lymphoblastic, T-Cell

Leukemia, T-Cell Acute Lymphoblastic

Leukemia, Acute T-Cell

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Precursor T-Cell Lymphoblastic Lymphoma

Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05158 FUT7 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris FUT7 VGNC VGNC:41014
Macaca mulatta FUT7 VGNC VGNC:103267
Rattus norvegicus FUT7 RGD RGD:735019
Felis catus FUT7 VGNC VGNC:102931
Bos taurus FUT7 VGNC VGNC:29151
Mus musculus FUT7 MGD MGI:107692
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