2. Gene
  3. Cst3 - cystatin C Gene

Cst3 - cystatin C Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: CYSC

基因 ID: 25307 | 基因类型: protein coding

关于 Cst3

功能概要

Enables peptidase inhibitor activity and Protease binding activity. Involved in several processes, including animal organ development; circadian sleep/wake cycle, REM sleep; and embryo implantation. Located in several cellular components, including multivesicular body; neuronal cell body; and nuclear membrane. Biomarker of intracranial aneurysm; iron deficiency anemia; and obesity. Human ortholog(s) of this gene implicated in CST3-related cerebral amyloid angiopathy and age related macular degeneration 11. Orthologous to several human genes including CST3 (Cystatin C). [provided by Alliance of Genome Resources, Apr 2022]

Cst3 基因产物(1)

mRNA Protein Name
NM_012837.1 NP_036969.1 cystatin-C precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables peptidase inhibitor activity IDA
IDA: 通过直接分析推断
8761177 RGD
enables protease binding IDA
IDA: 通过直接分析推断
2622871 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Sertoli cell development IEP
IEP: 通过表达模式推断
9432134 RGD
involved in cellular response to hydrogen peroxide IEP
IEP: 通过表达模式推断
17440810 RGD
involved in cellular response to oxidative stress IEP
IEP: 通过表达模式推断
10930551 RGD
involved in cellular response to oxidative stress IMP
IMP: 通过突变表型推断
16140167 RGD
involved in embryo implantation IEP
IEP: 通过表达模式推断
16935259 RGD
involved in eye development IEP
IEP: 通过表达模式推断
11431459 RGD
involved in male gonad development IEP
IEP: 通过表达模式推断
8286570 RGD
involved in positive regulation of DNA replication IDA
IDA: 通过直接分析推断
1540157 RGD
involved in positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
1540157 RGD
involved in response to axon injury IEP
IEP: 通过表达模式推断
8738161 RGD
involved in response to carbohydrate IEP
IEP: 通过表达模式推断
9222450 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
16935259 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
8590041 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
18723004 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
2757396 RGD
involved in response to toxic substance IEP
IEP: 通过表达模式推断
16414118 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
16248890 RGD
involved in salivary gland development IEP
IEP: 通过表达模式推断
10075146 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
14738488 RGD
located in basement membrane IDA
IDA: 通过直接分析推断
15872057 RGD
located in cell projection IDA
IDA: 通过直接分析推断
16309830 RGD
located in contractile muscle fiber IDA
IDA: 通过直接分析推断
8245434 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
2689174 RGD
located in multivesicular body IDA
IDA: 通过直接分析推断
10950881 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
14738488 RGD
located in nuclear membrane IDA
IDA: 通过直接分析推断
15872057 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
16414118 RGD
located in vesicle IDA
IDA: 通过直接分析推断
10950881 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cystatin-C

Cystatin C (cysteine proteinase inhibitor)

cystatin-3

重组 Cst3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74209 Cystatin C/CST3 Protein, Rat (HEK293, His) P14841 (M1-A140) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03264 CST3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cst3 NCBI NCBI:1471
Mus musculus Cst3 NCBI NCBI:13010
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