2. Gene
  3. Npy5r - neuropeptide Y receptor Y5 Gene

Npy5r - neuropeptide Y receptor Y5 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：神经肽 Y 受体 Y5

种属: Rattus norvegicus

同用名: NPYR5

基因 ID: 25340 | 基因类型: protein coding

关于 Npy5r

Cytogenetic location: 4q32.2 Genomic coordinates (GRCh38): 4:163,343,892-163,352,403 (from NCBI)

This gene has 3 transcripts (splice variants), 137 orthologues and 33 paralogues.

功能概要

该基因编码的蛋白可启动胰多肽受体活性和肽YY受体活性。参与多个过程，包括排卵周期节律的产生； GABA 能突触传递的负调节；和调节急性炎症反应。位于细胞质中。用于研究儿童失神性癫痫；高胰岛素血症;和视觉性癫痫。冠状动脉再狭窄的生物标志物；肥胖;和泌乳素瘤。该基因的人类直系同源物与脂质代谢紊乱和肥胖有关。与人 NPY5R（神经肽 Y 受体 Y5）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables pancreatic polypeptide receptor activity and peptide YY receptor activity. Involved in several processes, including generation of ovulation cycle rhythm; negative regulation of GABAergic synaptic transmission; and regulation of acute inflammatory response. Located in cytoplasm. Used to study childhood absence epilepsy; hyperinsulinism; and visual epilepsy. Biomarker of coronary restenosis; obesity; and prolactinoma. Human ortholog(s) of this gene implicated in lipid metabolism disorder and obesity. Orthologous to human NPY5R (Neuropeptide Y Receptor Y5). [provided by Alliance of Genome Resources, Apr 2022]

Npy5r 基因产物(3)

mRNA Protein Name
NM_012869.2 NP_037001.1 neuropeptide Y receptor type 5
XM_006253014.4 XP_006253076.1 neuropeptide Y receptor type 5 isoform X1
NM_012869.2 NP_037001.1 neuropeptide Y receptor type 5

Npy5r 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (58 - 425)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 445 a.a.
蛋白主名 其他名称

neuropeptide Y receptor type 5

NPY-Y5 receptor

NPY5-R

NPYY5-R

Neuropeptide Y5 receptor

Y5 receptor

关联疾病

疾病名称 别名
Panic Disorder

Panic Anxiety Syndrome

Panic

Panic Disorder 1

Episodic Paroxysmal Anxiety Disorder
Body Mass Index Quantitative Trait Locus 11

OBESITY

Obesity, Susceptibility To

Leanness, Inherited

Obesity, Susceptibility To, Bmiq11

Obesity, Mild, Early-Onset

Obesity, Association With

Obesity, Early-Onset, Susceptibility To

Obesity, Severe

Obesity, Severe, And Type Ii Diabetes

Obesity, Late-Onset

BMIQ11

Obesity Bmiq11

Obesity, Early-Onset

Obesity , Susceptibility To

Simple Obesity Nos

Excess Fat

Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified

Adiposis
Neuroblastoma

Nb

Neuroblastoma, Susceptibility To

Neuroblastomas

Central Neuroblastoma
Dihydropyrimidinase Deficiency

Dihydropyrimidinuria

Dpys Deficiency

Dph Deficiency

DPYSD

Dihydrouracil Amidohydrolase Deficiency

Dihydropyrimidinuria Due To Dpys Deficiency
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-107734 L 152804 Antagonist 99.48% 否
HY-RS09520 NPY5R Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS09521 Npy5r Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS09522 Npy5r Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Npy5r NCBI NCBI:4889
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z