1. Gene
  2. Ptgfr - prostaglandin F receptor Gene

Ptgfr - prostaglandin F receptor Gene

中文名称:前列腺素 F 受体

种属: Rattus norvegicus

同用名: PF2AR

基因 ID: 25652 | 基因类型: protein coding

关于 Ptgfr

Primary_assembly 2: 240,733,375-240,765,650 reverse strand.mRatBN7.2:CM026975.1

This gene has 1 transcript (splice variant), 195 orthologues, 8 paralogues and is associated with 2 phenotypes. Biased expression in Heart (RPKM 285.1), Liver (RPKM 73.) and 4 other tissues.

功能概要

预测该基因编码的蛋白编码的蛋白可启动前列腺素F受体活性。预计参与多个过程,包括使用细胞内钙源的钙介导信号;细胞对前列腺素 D 刺激的反应;和对雌二醇的反应。预计在细胞凋亡过程的负调节和对脂多糖的反应的上游或负调节内起作用。预测位于细胞质和细胞外区域。预计在质膜上有活性。与人 PTGFR(前列腺素 F 受体)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable prostaglandin F receptor activity. Predicted to be involved in several processes, including calcium-mediated signaling using intracellular calcium source; cellular response to prostaglandin D stimulus; and response to estradiol. Predicted to act upstream of or within negative regulation of apoptotic process and response to lipopolysaccharide. Predicted to be located in cytoplasm and extracellular region. Predicted to be active in plasma membrane. Orthologous to human PTGFR (prostaglandin F receptor). [provided by Alliance of Genome Resources, Apr 2022]

Ptgfr 基因产物(1)

mRNA Protein Name
NM_013115.2 NP_037247.1 prostaglandin F2-alpha receptor

Ptgfr 蛋白结构

7tmA_FP

7tmA_FP: cd15145 (26 - 315)

7tmA_FP

7tmA_FP: cd15145 (27 - 53)

7tmA_FP

7tmA_FP: cd15145 (65 - 91)

7tmA_FP

7tmA_FP: cd15145 (107 - 137)

7tmA_FP

7tmA_FP: cd15145 (149 - 171)

7tmA_FP

7tmA_FP: cd15145 (196 - 225)

7tmA_FP

7tmA_FP: cd15145 (241 - 271)

7tmA_FP

7tmA_FP: cd15145 (282 - 307)

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  • 366 a.a.
蛋白主名 其他名称

prostaglandin F2-alpha receptor

PGF receptor

PGF2-alpha receptor

prostanoid FP receptor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptgfr NCBI NCBI:5737
Macaca fascicularis Ptgfr NCBI NCBI:102139926
Mus musculus Ptgfr NCBI NCBI:19220