RAB26 - RAB26, member RAS oncogene family Gene

中文名称：RAB26，RAS 致癌基因家族成员

种属: Homo sapiens

同用名: V46133

基因 ID: 25837 | 基因类型: protein coding

关于 RAB26

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:2,148,144-2,154,165 (from NCBI)

This gene has 8 transcripts (splice variants), 250 orthologues and 68 paralogues. Broad expression in brain (RPKM 4.5), salivary gland (RPKM 3.5) and 15 other tissues.

功能概要

RAB 蛋白家族的成员，包括 RAB26，是囊泡融合和运输的重要调节因子。小 G 蛋白的 RAB 家族调节细胞间囊泡运输，包括胞吐作用、胞吞作用和再循环 (Seki 等人总结，2000 [PubMed 11043516]) 。[OMIM 提供，2010 年 11 月]

Members of the RAB protein family, including RAB26, are important regulators of vesicular fusion and trafficking. The RAB family of small G proteins regulates intercellular vesicle trafficking, including exocytosis, endocytosis, and recycling (summary by Seki et al., 2000 [PubMed 11043516]).[supplied by OMIM, Nov 2010]

RAB26 基因产物(2)

mRNA	Protein	Name
NM_001308053.1	NP_001294982.1	ras-related protein Rab-26 isoform 2
NM_014353.5	NP_055168.2	ras-related protein Rab-26 isoform 1

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables GMP binding	IMP IMP: 通过突变表型推断	23105096	GOA
enables GTP binding	IMP IMP: 通过突变表型推断	23105096	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	23105096	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in Golgi to plasma membrane protein transport	IMP IMP: 通过突变表型推断	23105096	GOA
involved in exocrine system development	IMP IMP: 通过突变表型推断	20038531	GOA
involved in regulated exocytosis	IMP IMP: 通过突变表型推断	20038531	GOA
involved in regulation protein catabolic process at presynapse	IDA IDA: 通过直接分析推断	29084947	GOA
involved in regulation protein catabolic process at presynapse	IMP IMP: 通过突变表型推断	29084947	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in Golgi membrane	IDA IDA: 通过直接分析推断	23105096	GOA
is active in synaptic vesicle membrane	IDA IDA: 通过直接分析推断	25643395	GOA
is active in synaptic vesicle membrane	IMP IMP: 通过突变表型推断	25643395	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RAB26 蛋白结构

Ras

0
100
200
256 a.a.

蛋白主名

其他名称

ras-related protein Rab-26

Ras-related oncogene protein

RAB26 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	RAB26	Q9ULW5	KRT33B	Homo sapiens	Q14525	Y2H Array	32296183
种属内	RAB26	Q9ULW5	KRT33B	Homo sapiens	Q14525	Y2H Prey Pooling	32296183
种属内	RAB26	Q9ULW5	UNKL	Homo sapiens	Q9H9P5-5	Y2H Array	32296183
种属内	RAB26	Q9ULW5	UNKL	Homo sapiens	Q9H9P5-5	Y2H Prey Pooling	32296183
种属内	RAB26	Q9ULW5	OIP5	Homo sapiens	O43482	Y2H Array	32296183
种属内	RAB26	Q9ULW5	OIP5	Homo sapiens	O43482	Y2H Prey Pooling	32296183
种属内	RAB26	Q9ULW5	FHL5	Homo sapiens	Q5TD97	Y2H Array	32296183
种属内	RAB26	Q9ULW5	ADRA2B	Homo sapiens	P18089	Anti Bait CoIP	23105096
种属内	RAB26	Q9ULW5	ADRA2B	Homo sapiens	P18089	Pull Down	23105096
种属内	RAB26	Q9ULW5	ADRA2B	Homo sapiens	P18089	BRET	23105096

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Spastic Paraplegia 15, Autosomal Recessive

SPG15	Kjellin Syndrome
Hereditary Spastic Paraplegia 15	Spastic Paraplegia And Retinal Degeneration
Autosomal Recessive Spastic Paraplegia Type 15	Hereditary Spastic Paraparesis Type 15
Spastic Paraplegia-Retinal Degeneration Syndrome	Autosomal Recessive Spastic Paraplegia 15

Spinal Muscular Atrophy, Distal, Autosomal Recessive, 4

DSMA4	Autosomal Recessive Lower Motor Neuron Disease With Childhood Onset
Distal Spinal Muscular Atrophy Type 4	Autosomal Recessive Distal Spinal Muscular Atrophy Type 4
Distal Spinal Muscular Atrophy, Autosomal Recessive, 4	Atrophy, Muscular, Spinal, Distal, Autosomal Recessive, Type 4

Spinal Muscular Atrophy, Type Iv

SMA4	Spinal Muscular Atrophy, Adult Form
Spinal Muscular Atrophy 4	Spinal Muscular Atrophy-4
Adult Spinal Muscular Atrophy	Spinal Muscular Atrophy, Proximal, Adult, Autosomal Recessive
Proximal Spinal Muscular Atrophy Type 4	Sma Type 4
Sma Type Iv	Sma-Iv
Sma Iv	Spinal Muscular Atrophy Adult Form
Spinal Muscular Atrophy Proximal Adult Autosomal Recessive	Spinal Muscular Atrophy Type Iv
Atrophy, Muscular, Spinal, Type Iv	Myelopathic Muscular Atrophy

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS11536	RAB26 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	RAB26	VGNC	VGNC:80677
Mus musculus	RAB26	MGD	MGI:2443284
Bos taurus	RAB26	VGNC	VGNC:33633
Macaca mulatta	RAB26	VGNC	VGNC:81526
Rattus norvegicus	RAB26	RGD	RGD:620890
Canis familiaris	RAB26	VGNC	VGNC:45266

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站点地图隐私声明

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上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

RAB26 - RAB26, member RAS oncogene family Gene

关于 RAB26

功能概要

RAB26 基因产物(2)

RAB26 蛋白结构

RAB26 蛋白互作信息

关联疾病

直系同源

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RAB26 - RAB26, member RAS oncogene family Gene

关于 RAB26

功能概要

RAB26 基因产物(2)

RAB26 蛋白结构

RAB26 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

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C

F

G

H

J

L

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Q

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T

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