1. Gene
  2. Cul1 - cullin 1 Gene

Cul1 - cullin 1 Gene

种属: Mus musculus

同用名: Cul-1

基因 ID: 26965 | 基因类型: protein coding

关于 Cul1

功能概要

Predicted to enable ubiquitin protein Ligase binding activity and ubiquitin-protein transferase activity. Predicted to contribute to ubiquitin protein Ligase activity. Involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Acts upstream of or within several processes, including animal organ morphogenesis; apoptotic process; and protein ubiquitination. Part of SCF ubiquitin Ligase complex. Is expressed in several structures, including adrenal gland; genitourinary system; immune system; neural retina; and telencephalon. Orthologous to human CUL1 (cullin 1). [provided by Alliance of Genome Resources, Apr 2022]

Cul1 基因产物(7)

mRNA Protein Name
NM_001355550.2 NP_001342479.1 cullin-1
NM_001355551.2 NP_001342480.1 cullin-1
NM_001410599.1 NP_001397528.1 cullin-1
NM_001410600.1 NP_001397529.1 cullin-1
NM_001410601.1 NP_001397530.1 cullin-1
NM_001410602.1 NP_001397531.1 cullin-1
NM_012042.5 NP_036172.1 cullin-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12665572 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IDA
IDA: 通过直接分析推断
12140560 MGI
acts upstream of or within animal organ morphogenesis IMP
IMP: 通过突变表型推断
10508527 MGI
acts upstream of or within apoptotic process IMP
IMP: 通过突变表型推断
10508527 MGI
acts upstream of or within cell population proliferation IMP
IMP: 通过突变表型推断
10508527 MGI
acts upstream of or within protein K48-linked ubiquitination IDA
IDA: 通过直接分析推断
29593216 MGI
acts upstream of or within protein monoubiquitination IGI
IGI: 通过遗传相互作用推断
21343341 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of SCF ubiquitin ligase complex IDA
IDA: 通过直接分析推断
12140560 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

cullin-1

Cul1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Cul1 Q9WTX6 UBXN7 Homo sapiens O94888 22466964
种属间
Cul1 Q9WTX6 VCP Homo sapiens P55072 22466964
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cul1 NCBI NCBI:8454