USP21 - ubiquitin specific peptidase 21 Gene

中文名称：泛素特异性肽酶 21

种属: Homo sapiens

同用名: USP16; USP23

关于 USP21

功能概要

该基因编码 C19 肽酶家族的成员，也称为泛素羧基末端水解酶家族 2。编码的蛋白质从泛素化蛋白质中切割泛素，以便在细胞内蛋白质降解中回收。编码的蛋白质还能够从 NEDD8 偶联蛋白中释放 NEDD8，一种泛素样蛋白。该基因曾被称为 USP16 和 USP23，但现在被称为 USP21。已发现该基因编码不同亚型的可变剪接转录物变体。[RefSeq 提供，2016 年 2 月]

This gene encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquitin-like protein, from NEDD8-conjugated proteins. This gene has been referred to as USP16 and USP23 but is now known as USP21. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]