1. Gene
  2. TRAPPC3 - trafficking protein particle complex subunit 3 Gene

TRAPPC3 - trafficking protein particle complex subunit 3 Gene

中文名称:运输蛋白颗粒复合物亚基 3

种属: Homo sapiens

同用名: BET3

基因 ID: 27095 | 基因类型: protein coding

关于 TRAPPC3

Cytogenetic location: 1p34.3 Genomic coordinates (GRCh38): 1:36,136,572-36,156,053 (from NCBI)

This gene has 10 transcripts (splice variants), 213 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 23.9), adrenal (RPKM 19.7) and 25 other tissues.

功能概要

该基因编码运输蛋白颗粒复合物的一个组成部分,该复合物将囊泡输送到顺式高尔基体膜。编码的蛋白质参与调节从内质网到高尔基体的运输。可变剪接导致多个转录本变体。[RefSeq 提供,2012 年 8 月]

This gene encodes a component of the trafficking protein particle complex, which tethers transport vesicles to the cis-Golgi membrane. The encoded protein participates in the regulation of transport from the endoplasmic reticulum to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

TRAPPC3 基因产物(5)

mRNA Protein Name
NM_001270894.2 NP_001257823.1 trafficking protein particle complex subunit 3 isoform 2
NM_001270895.2 NP_001257824.1 trafficking protein particle complex subunit 3 isoform 3
NM_001270896.2 NP_001257825.1 trafficking protein particle complex subunit 3 isoform 3
NM_001270897.2 NP_001257826.1 trafficking protein particle complex subunit 3 isoform 4
NM_014408.5 NP_055223.1 trafficking protein particle complex subunit 3 isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of TRAPP complex IDA
IDA: 通过直接分析推断
21525244 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

TRAPPC3 蛋白结构

TRAPP

TRAPP: Transport protein particle (TRAPP) component (18 - 166)

  • 0
  • 100
  • 180 a.a.
蛋白主名 其他名称

trafficking protein particle complex subunit 3

trafficking protein particle complex 3

TRAPPC3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra TRAPPC3 O43617 TRAPPC2L Homo sapiens Q9UL33-2
Y2H Array
32296183
Intra TRAPPC3 O43617 TRAPPC2L Homo sapiens Q9UL33-2
Validated Y2H
32296183
Intra TRAPPC3 O43617 TRAPPC2L Homo sapiens Q9UL33-2
Y2H Prey Pooling
32296183
Intra TRAPPC3 O43617 TRAPPC2 Homo sapiens P0DI81-3
Y2H Prey Pooling
32296183
Intra TRAPPC3 O43617 TRAPPC2 Homo sapiens P0DI81-3
Validated Y2H
32296183
Intra TRAPPC3 O43617 TRAPPC2 Homo sapiens P0DI81-3
Y2H Array
32296183
Intra TRAPPC3 O43617 TRAPPC13 Homo sapiens A5PLN9
Anti Tag CoIP
21453443
Intra TRAPPC3 O43617 TRAPPC5 Homo sapiens Q8IUR0
Y2H Prey Pooling
32296183
Intra TRAPPC3 O43617 TRAPPC5 Homo sapiens Q8IUR0
Validated Y2H
32296183
Intra TRAPPC3 O43617 TRAPPC5 Homo sapiens Q8IUR0
Y2H Array
32296183
Intra TRAPPC3 O43617 TRAPPC6B Homo sapiens Q86SZ2
Anti Bait CoIP
18930054
Intra TRAPPC3 O43617 TRAPPC6B Homo sapiens Q86SZ2
Anti Tag CoIP
16908848
Intra TRAPPC3 O43617 TRAPPC1 Homo sapiens Q9Y5R8
Y2H Array
32296183
Intra TRAPPC3 O43617 TRAPPC1 Homo sapiens Q9Y5R8
Y2H Prey Pooling
32296183
Intra TRAPPC3 O43617 TRAPPC1 Homo sapiens Q9Y5R8
Validated Y2H
32296183
Intra TRAPPC3 O43617 PLEKHF2 Homo sapiens Q9H8W4
Y2H Array
25416956
Intra TRAPPC3 O43617 PLEKHF2 Homo sapiens Q9H8W4
Validated Y2H
25416956
Intra TRAPPC3 O43617 TRAPPC6A Homo sapiens O75865
Y2H Pooling
16189514
Intra TRAPPC3 O43617 TRAPPC6A Homo sapiens O75865
Y2H Prey Pooling
25416956
Intra TRAPPC3 O43617 TRAPPC6A Homo sapiens O75865
Validated Y2H
25416956
Intra TRAPPC3 O43617 TRAPPC6A Homo sapiens O75865
Y2H Array
25416956
Intra TRAPPC3 O43617 TRAPPC6A Homo sapiens O75865
Anti Bait CoIP
18930054
Intra TRAPPC3 O43617 TRAPPC2L Homo sapiens Q9UL33
Y2H Pooling
16189514
Intra TRAPPC3 O43617 TRAPPC2L Homo sapiens Q9UL33
Y2H Prey Pooling
25416956
Intra TRAPPC3 O43617 TRAPPC6A Homo sapiens O75865-2
Anti Bait CoIP
18930054
Intra TRAPPC3 O43617 TRAPPC6A Homo sapiens O75865-2
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Spondyloepiphyseal Dysplasia Tarda, X-Linked

Spondyloepiphyseal Dysplasia Tarda

X-Linked Spondyloepiphyseal Dysplasia Tarda

SEDT

Sed Tarda, X-Linked

Spondyloepiphyseal Dysplasia, Late

Spondyloepiphyseal Dysplasia Tarda X-Linked

Sed

X Linked Spondyloepiphyseal Dysplasia Tarda

X-Linked Spondyloepiphyseal Dysplasia

Late Onset Spondyloepiphyseal Dysplasia

Sed Tarda

X-Linked Sed

X-Linked Sedt

Dysplasia, Spondyloepiphyseal, Tarda

Spondyloepiphyseal Dysplasia

Bardet-Biedl Syndrome

Bbs

Biedl-Bardet Syndrome

Celery Allergy
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus TRAPPC3 RGD RGD:1309135
Mus musculus TRAPPC3 MGD MGI:1351486
Felis catus TRAPPC3 VGNC VGNC:107683
Canis familiaris TRAPPC3 VGNC VGNC:47781
Macaca mulatta TRAPPC3 VGNC VGNC:79210
Bos taurus TRAPPC3 VGNC VGNC:36288