1. Gene
  2. INO80E - INO80 complex subunit E Gene

INO80E - INO80 complex subunit E Gene

中文名称:INO80 复合亚基 E

种属: Homo sapiens

同用名: CCDC95

基因 ID: 283899 | 基因类型: protein coding

关于 INO80E

This gene has 14 transcripts (splice variants) and 181 orthologues. Ubiquitous expression in testis (RPKM 18.0), spleen (RPKM 15.7) and 25 other tissues.

功能概要

预测参与 DNA 重组; DNA 修复;和染色质重塑。位于核仁和核质中。 Ino80 复合体的一部分。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in DNA recombination; DNA repair; and chromatin remodeling. Located in nucleolus and nucleoplasm. Part of Ino80 complex. [provided by Alliance of Genome Resources, Apr 2022]

INO80E 基因产物(3)

mRNA Protein Name
NM_001304562.2 NP_001291491.1 INO80 complex subunit E isoform 2
NM_001304563.2 NP_001291492.1 INO80 complex subunit E isoform 3
NM_173618.3 NP_775889.1 INO80 complex subunit E isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16230350 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in chromatin remodeling IDA
IDA: 通过直接分析推断
21303910 GOA
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
27641337 GOA
involved in regulation of DNA replication IMP
IMP: 通过突变表型推断
25016522 GOA
involved in regulation of DNA strand elongation IMP
IMP: 通过突变表型推断
25016522 GOA
involved in regulation of cell cycle IMP
IMP: 通过突变表型推断
26340092 GOA
involved in regulation of chromosome organization IMP
IMP: 通过突变表型推断
26340092 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of Ino80 complex IDA
IDA: 通过直接分析推断
21303910 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

INO80 complex subunit E

coiled-coil domain containing 95

关联疾病

疾病名称 别名
Schizophrenia 3

SCZD3

Schizophrenia Susceptibility Locus, Chromosome 6-Related

Schizophrenia 3 With Or Without An Affective Disorder

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus INO80E RGD RGD:1359572
Bos taurus INO80E VGNC VGNC:30207
Macaca mulatta INO80E VGNC VGNC:73663
Felis catus INO80E VGNC VGNC:62928
Mus musculus INO80E MGD MGI:2141881
Canis familiaris INO80E VGNC VGNC:42026