1. Gene
  2. MCTS1 - MCTS1 re-initiation and release factor Gene

MCTS1 - MCTS1 re-initiation and release factor Gene

中文名称:MCTS1 重新启动和释放因子

种属: Homo sapiens

同用名: MCT1; MCT-1

基因 ID: 28985 | 基因类型: protein coding

关于 MCTS1

Cytogenetic location: Xq24 Genomic coordinates (GRCh38): X:120,604,101-120,621,159 (from NCBI)

This gene has 6 transcripts (splice variants), 1 gene allele, 206 orthologues and 1 paralogue. Ubiquitous expression in lymph node (RPKM 3.6), brain (RPKM 3.4) and 25 other tissues.

功能概要

预测启用翻译启动因子活动。参与 IRES 依赖性病毒翻译启动;翻译预启动复合体的形成;和核糖体分解。位于胞质溶胶和质膜中。与胞质小核糖体亚基共定位。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable translation initiation factor activity. Involved in IRES-dependent viral translational initiation; formation of translation preinitiation complex; and ribosome disassembly. Located in cytosol and plasma membrane. Colocalizes with cytosolic small ribosomal subunit. [provided by Alliance of Genome Resources, Apr 2022]

MCTS1 基因产物(2)

mRNA Protein Name
NM_001137554.2 NP_001131026.1 malignant T-cell-amplified sequence 1 isoform 2
NM_014060.3 NP_054779.1 malignant T-cell-amplified sequence 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA cap binding IDA
IDA: 通过直接分析推断
16982740 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
16169070 GOA
enables ribosomal small subunit binding IDA
IDA: 通过直接分析推断
20713520 GOA
enables translation factor activity, non-nucleic acid binding IDA
IDA: 通过直接分析推断
20713520 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in IRES-dependent viral translational initiation IDA
IDA: 通过直接分析推断
20713520 GOA
involved in formation of translation preinitiation complex IDA
IDA: 通过直接分析推断
20713520 GOA
involved in ribosome disassembly IDA
IDA: 通过直接分析推断
20713520 GOA
involved in ribosome disassembly IMP
IMP: 通过突变表型推断
37875108 GOA
involved in translation reinitiation IMP
IMP: 通过突变表型推断
37875108 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cytoplasm IDA
IDA: 通过直接分析推断
16982740 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

MCTS1 蛋白结构

PUA

PUA: PUA domain (94 - 170)

  • 0
  • 100
  • 181 a.a.
蛋白主名 其他名称

malignant T-cell-amplified sequence 1

malignant T-cell amplified sequence 1

MCTS1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
MCTS1 Q9ULC4 DENR Homo sapiens O43583
Anti Tag CoIP
33961781
种属内
MCTS1 Q9ULC4 DENR Homo sapiens O43583
Y2H Prey Pooling
32296183
种属内
MCTS1 Q9ULC4 DENR Homo sapiens O43583
Y2H Array
32296183
种属内
MCTS1 Q9ULC4 DENR Homo sapiens O43583
Y2H Pooling
16169070
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Lymphoma

Lymphoid Cancer

Lymphomas

Lymphoid Cancers

Lymphoid Neoplasm

Lymphoma Nos

Nhl - [Non-Hodgkin Lymphoma]

Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma, Nos

Non-Hodgkin Malignant Lymphoma Nos

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris MCTS1 VGNC VGNC:54172
Rattus norvegicus MCTS1 RGD RGD:1566390
Mus musculus MCTS1 MGD MGI:1916245
Macaca mulatta MCTS1 VGNC VGNC:74558
Bos taurus MCTS1 VGNC VGNC:56930