2. Gene
  3. Tjp1 - tight junction protein 1 Gene

Tjp1 - tight junction protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: ZO-1

基因 ID: 292994 | 基因类型: protein coding

关于 Tjp1

功能概要

Enables protein C-terminus binding activity. Involved in several processes, including cellular response to glucose stimulus; negative regulation of vascular permeability; and response to lipopolysaccharide. Located in bicellular tight junction; cytoplasm; and gap junction. Biomarker of several diseases, including brain ischemia; cholestasis; peptic esophagitis; perinatal necrotizing enterocolitis; and uveitis. Orthologous to human TJP1 (tight junction protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Tjp1 基因产物(1)

mRNA Protein Name
NM_001106266.1 NP_001099736.1 tight junction protein ZO-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables beta-catenin binding IPI
IPI: 通过物理相互作用推断
12960056 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
16617054 RGD
enables transmembrane transporter binding IPI
IPI: 通过物理相互作用推断
15980428 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to glucose stimulus IEP
IEP: 通过表达模式推断
16567508 RGD
involved in negative regulation of vascular permeability IEP
IEP: 通过表达模式推断
20137299 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
17515855 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
17515855 RGD
involved in response to magnetism IEP
IEP: 通过表达模式推断
20137299 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
18360096 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in bicellular tight junction IDA
IDA: 通过直接分析推断
17899156 RGD
located in cell-cell junction IDA
IDA: 通过直接分析推断
25486565 RGD
located in gap junction IDA
IDA: 通过直接分析推断
29021339 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tight junction protein ZO-1

zona occludens 1

zona occludens protein 1

zonula occludens protein 1

Tjp1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Tjp1 F1M4A0 Ocln Rattus norvegicus Q6P6T5
Anti Bait CoIP
22106313
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14553 TJP1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tjp1 NCBI NCBI:7082
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z