Glo1 - glyoxalase 1 Gene

中文名称：乙二醛酶1

种属: Rattus norvegicus

关于 Glo1

功能概要

该基因编码的蛋白可启动乳酰谷胱甘肽裂解酶活性。参与碳水化合物代谢过程；谷胱甘肽代谢过程；和甲基乙二醛代谢过程。预测位于胞质溶胶中；核质；和质膜。该基因的人类直系同源物与自闭症有关；糖尿病性视网膜病变;晚期肾脏疾病; 2型糖尿病；和血管疾病。与人 GLO1（乙二醛酶 I）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables lactoylglutathione lyase activity. Involved in carbohydrate metabolic process; glutathione metabolic process; and methylglyoxal metabolic process. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Human ortholog(s) of this gene implicated in autistic disorder; diabetic retinopathy; end stage renal disease; type 2 diabetes mellitus; and vascular disease. Orthologous to human GLO1 (glyoxalase I). [provided by Alliance of Genome Resources, Apr 2022]