Plk4 - polo-like kinase 4 Gene

中文名称：马球样激酶 4

种属: Rattus norvegicus

关于 Plk4

功能概要

预计该基因编码的蛋白具有相同的蛋白质结合活性和蛋白质丝氨酸/苏氨酸激酶活性。预计参与多个过程，包括细胞器组装；调节细胞周期过程；和滋养层巨细胞分化。预测位于多个细胞成分中，包括XY体；中心粒;和氘核。预计在细胞质中有活性；微管细胞骨架；和核。该基因的人类直向同源物与小头畸形和脉络膜视网膜病变 2 相关。与人类 PLK4（马球样激酶 4）直向同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable identical protein binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including organelle assembly; regulation of cell cycle process; and trophoblast giant cell differentiation. Predicted to be located in several cellular components, including XY body; centriole; and deuterosome. Predicted to be active in cytoplasm; microtubule cytoskeleton; and nucleus. Human ortholog(s) of this gene implicated in microcephaly and chorioretinopathy 2. Orthologous to human PLK4 (polo like kinase 4). [provided by Alliance of Genome Resources, Apr 2022]