Tlr2 - toll-like receptor 2 Gene

中文名称：Toll样受体 2

种属: Rattus norvegicus

关于 Tlr2

功能概要

该基因编码的蛋白可启动脂肽结合活性。参与几个过程，包括神经发生；白细胞介素 10 产生的正向调节；和对细菌起源分子的反应。位于细胞体内；细胞投影；和细胞表面。用于研究颈动脉狭窄；回肠炎;角膜炎;肺部疾病（多发）；和肾纤维化。急性坏死性胰腺炎的生物标志物；肾功能衰竭;肺部疾病;胰腺炎;和围产期坏死性小肠结肠炎。该基因的人类直系同源物与多种疾病有关，包括自身免疫性疾病（多种）；皮炎（多发性）；胃肠系统癌症（多发性）；肺部疾病（多发）；和鼻炎（多种）。与人类 TLR2（toll 样受体 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables Lipopeptide binding activity. Involved in several processes, including neurogenesis; positive regulation of interleukin-10 production; and response to molecule of Bacterial origin. Located in cell body; cell projection; and cell surface. Used to study carotid stenosis; ileitis; keratitis; lung disease (multiple); and renal fibrosis. Biomarker of acute necrotizing pancreatitis; kidney failure; lung disease; pancreatitis; and perinatal necrotizing enterocolitis. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dermatitis (multiple); gastrointestinal system Cancer (multiple); lung disease (multiple); and rhinitis (multiple). Orthologous to human TLR2 (Toll Like Receptor 2). [provided by Alliance of Genome Resources, Apr 2022]