2. Gene
  3. Nrcam - neuronal cell adhesion molecule Gene

Nrcam - neuronal cell adhesion molecule Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Bravo; mKIAA0343; C030017F07Rik; C130076O07Rik

基因 ID: 319504 | 基因类型: protein coding

关于 Nrcam

功能概要

Enables protein binding activity involved in heterotypic cell-cell adhesion. Involved in cell-cell adhesion; nervous system development; and regulation of postsynapse organization. Acts upstream of or within several processes, including neuron development; neuronal action potential propagation; and regulation of neuron projection development. Located in axon; plasma membrane; and synapse. Is integral component of postsynaptic density membrane. Is active in glutamatergic synapse. Is integral component of postsynaptic membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Used to study autism spectrum disorder. Orthologous to human NRCAM (neuronal cell adhesion molecule). [provided by Alliance of Genome Resources, Apr 2022]

Nrcam 基因产物(2)

mRNA Protein Name
NM_001146031.1 NP_001139503.1 neuronal cell adhesion molecule isoform 2 precursor
NM_176930.4 NP_795904.3 neuronal cell adhesion molecule isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16882004 MGI
enables protein binding involved in heterotypic cell-cell adhesion IGI
IGI: 通过遗传相互作用推断
20188654 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in axon guidance IDA
IDA: 通过直接分析推断
12182881 MGI
involved in cell-cell adhesion IDA
IDA: 通过直接分析推断
12182881 MGI
involved in central nervous system development IDA
IDA: 通过直接分析推断
12182881 MGI
acts upstream of or within clustering of voltage-gated sodium channels IMP
IMP: 通过突变表型推断
20188654 MGI
acts upstream of or within neuronal action potential propagation IMP
IMP: 通过突变表型推断
14602817 MGI
acts upstream of or within protein localization IDA
IDA: 通过直接分析推断
16882004 MGI
acts upstream of or within regulation of neuron projection development IMP
IMP: 通过突变表型推断
16701205 MGI
involved in regulation of postsynapse organization IDA
IDA: 通过直接分析推断
25143608 MGI
involved in regulation of postsynapse organization IMP
IMP: 通过突变表型推断
25143608 MGI
acts upstream of or within retinal ganglion cell axon guidance IMP
IMP: 通过突变表型推断
16701205 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
14602817 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
25143608 MGI
is active in glutamatergic synapse IEP
IEP: 通过表达模式推断
25143608 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
25143608 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
16882004 MGI
is active in postsynaptic density membrane IDA
IDA: 通过直接分析推断
25143608 MGI
is active in postsynaptic density membrane IEP
IEP: 通过表达模式推断
25143608 MGI
is active in postsynaptic membrane IDA
IDA: 通过直接分析推断
25143608 MGI
located in synapse IDA
IDA: 通过直接分析推断
16882004 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neuronal cell adhesion molecule

mBravo

neuron-glia-CAM-related cell adhesion molecule

neuronal surface protein Bravo

ng-CAM-related

ngCAM-related cell adhesion molecule

nr-CAM

Nrcam 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Nrcam Q810U4 Dlg1 Mus musculus Q811D0
Y2H Array
16882004
种属内
Nrcam Q810U4 Dlg1 Mus musculus Q811D0
Imaging
16882004
种属内
Nrcam Q810U4 Dlg1 Mus musculus Q811D0
Pull Down
16882004
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09563 NRCAM Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nrcam NCBI NCBI:4897
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