2. Gene
  3. HSF2 - heat shock transcription factor 2 Gene

HSF2 - heat shock transcription factor 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：热休克转录因子 2

种属: Homo sapiens

同用名: HSF 2; HSTF 2

基因 ID: 3298 | 基因类型: protein coding

关于 HSF2

Cytogenetic location: 6q22.31 Genomic coordinates (GRCh38): 6:122,399,551-122,433,119 (from NCBI)

This gene has 3 transcripts (splice variants), 209 orthologues and 9 paralogues. Broad expression in testis (RPKM 22.1), bone marrow (RPKM 8.8) and 23 other tissues.

功能概要

该基因编码的蛋白质属于 HSF 转录因子家族，可特异性结合热休克启动子元件并激活转录。热休克转录因子在热或其他应激条件下激活热休克反应基因。已发现该基因编码不同亚型的可变剪接转录物变体。[RefSeq 提供，2011 年 7 月]

The protein encoded by this gene belongs to the HSF family of transcription factors that bind specifically to the heat-shock promoter element and activate transcription. Heat shock transcription factors activate heat-shock response genes under conditions of heat or other stresses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

HSF2 基因产物(3)

mRNA Protein Name
NM_001135564.1 NP_001129036.1 heat shock factor protein 2 isoform b
NM_001243094.2 NP_001230023.1 heat shock factor protein 2 isoform c
NM_004506.4 NP_004497.1 heat shock factor protein 2 isoform a

HSF2 蛋白结构

HSF_DNA-bind

HSF_DNA-bind: HSF-type DNA-binding (9 - 113)

Vert_HS_TF

Vert_HS_TF: Vertebrate heat shock transcription factor (229 - 512)

  • 0
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  • 500
  • 536 a.a.
蛋白主名 其他名称

heat shock factor protein 2

重组 HSF2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70406 HSF2 Protein, Human (His) Q03933 (S411-S536) ≥95%

关联疾病

疾病名称 别名
Spermatogenic Failure 10

SPGF10

Spermatogenic Failure With Defective Sperm Annulus
Spermatogenic Failure 14

SPGF14
Erythroleukemia
Spermatogenic Failure 15

SPGF15

Spermatogenic Failure, 15
Spermatogenic Failure, Y-Linked, 2

SPGFY2

Spermatogenic Failure, Nonobstructive, Y-Linked

Y-Linked Spermatogenic Failure 2

Azoospermia, Nonobstructive, Y-Linked

Oligozoospermia, Nonobstructive, Y-Linked

Oligospermia, Nonobstructive, Y-Linked

Spermatogenic Arrest, Y-Linked

Nonobstructive Y-Linked Spermatogenic Failure

Spermatogenic Failure Y-Linked 2

Azoospermia Non-Obstructive Y-Linked

Non-Obstructive Azoospermia And Infertility

Oligospermia Non-Obstructive Y-Linked

Oligozoospermia Non-Obstructive Y-Linked

Spermatogenic Arrest Y-Linked

Spermatogenic Failure Nonobstructive Y-Linked
Spermatogenic Failure

Azoospermia

Spgf

Spermatogenic Failure, Susceptibility To

Absent Sperm

Aspermatogenesis

Infertility Due To Azoospermia

Hypospermatogenesis

Azoospermatism
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06409 HSF2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS06410 HSF2BP Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus HSF2 VGNC VGNC:29982
Canis familiaris HSF2 VGNC VGNC:41815
Felis catus HSF2 VGNC VGNC:67662
Macaca mulatta HSF2 VGNC VGNC:81077
Mus musculus HSF2 MGD MGI:96239
Rattus norvegicus HSF2 RGD RGD:68395
Others HSF2 NCBI
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