1. Gene
  2. KRT79 - keratin 79 Gene

KRT79 - keratin 79 Gene

中文名称:角蛋白 79

种属: Homo sapiens

同用名: K6L; KRT6L

基因 ID: 338785 | 基因类型: protein coding

关于 KRT79

Cytogenetic location: 12q13.13 Genomic coordinates (GRCh38): 12:52,821,408-52,834,311 (from NCBI)

This gene has 3 transcripts (splice variants), 84 orthologues and 68 paralogues. Biased expression in skin (RPKM 6.3), fat (RPKM 0.8) and 1 other tissue.

功能概要

角蛋白是负责上皮细胞结构完整性的中间丝蛋白,分为上皮角蛋白和毛发角蛋白。该基因编码一种在骨骼肌、皮肤和头皮中表达的上皮角蛋白。 II 型角蛋白聚集在染色体 12q13 的区域。[RefSeq 提供,2009 年 6 月]

Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes an epithelial keratin that is expressed in skeletal muscle, skin and scalp. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009]

KRT79 基因产物(1)

mRNA Protein Name
NM_175834.3 NP_787028.1 keratin, type II cytoskeletal 79
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables enzyme binding IPI
IPI: 通过物理相互作用推断
23382074 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

KRT79 蛋白结构

Filament

Filament: Intermediate filament protein (141 - 456)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 535 a.a.
蛋白主名 其他名称

keratin, type II cytoskeletal 79

CK-79

KRT79 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra KRT79 Q5XKE5 KRT13 Homo sapiens A1A4E9
Y2H Prey Pooling
25416956
Intra KRT79 Q5XKE5 KRT13 Homo sapiens A1A4E9
Y2H Array
25416956
Intra KRT79 Q5XKE5 SYCE3 Homo sapiens A1L190
Y2H Array
32296183
Intra KRT79 Q5XKE5 SYCE3 Homo sapiens A1L190
Y2H Prey Pooling
32296183
Intra KRT79 Q5XKE5 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
Intra KRT79 Q5XKE5 KRT34 Homo sapiens O76011
Y2H Array
32296183
Intra KRT79 Q5XKE5 KRT38 Homo sapiens O76015
Y2H Array
25416956
Intra KRT79 Q5XKE5 KRT38 Homo sapiens O76015
Y2H Array
29892012
Intra KRT79 Q5XKE5 KRT38 Homo sapiens O76015
Validated Y2H
25416956
Intra KRT79 Q5XKE5 KRT33B Homo sapiens Q14525
Y2H Prey Pooling
32296183
Intra KRT79 Q5XKE5 KRT33B Homo sapiens Q14525
Y2H Array
25416956
Intra KRT79 Q5XKE5 KRT33B Homo sapiens Q14525
Y2H Array
32296183
Intra KRT79 Q5XKE5 KRT33B Homo sapiens Q14525
Y2H Array
31515488
Intra KRT79 Q5XKE5 KRT35 Homo sapiens Q92764
Y2H Array
32296183
Intra KRT79 Q5XKE5 KRT35 Homo sapiens Q92764
Validated Y2H
32296183
Intra KRT79 Q5XKE5 KRT35 Homo sapiens Q92764
Y2H Prey Pooling
32296183
Intra KRT79 Q5XKE5 KRT36 Homo sapiens O76013-2
Y2H Array
32296183
Intra KRT79 Q5XKE5 KRT36 Homo sapiens O76013-2
Y2H Prey Pooling
32296183
Intra KRT79 Q5XKE5 KRT25 Homo sapiens Q7Z3Z0
Y2H Prey Pooling
32296183
Intra KRT79 Q5XKE5 KRT25 Homo sapiens Q7Z3Z0
Validated Y2H
32296183
Intra KRT79 Q5XKE5 KRT25 Homo sapiens Q7Z3Z0
Y2H Array
32296183
Intra KRT79 Q5XKE5 KRT28 Homo sapiens Q7Z3Y7
Validated Y2H
32296183
Intra KRT79 Q5XKE5 TRIM54 Homo sapiens Q9BYV2
Y2H Prey Pooling
32296183
Intra KRT79 Q5XKE5 TRIM54 Homo sapiens Q9BYV2
Validated Y2H
32296183
Intra KRT79 Q5XKE5 TRIM54 Homo sapiens Q9BYV2
Y2H Array
32296183
Intra KRT79 Q5XKE5 KRT24 Homo sapiens Q2M2I5
Y2H Array
32296183
Intra KRT79 Q5XKE5 KRT24 Homo sapiens Q2M2I5
Y2H Prey Pooling
32296183
Intra KRT79 Q5XKE5 KRT18 Homo sapiens P05783
Y2H Array
32296183
Intra KRT79 Q5XKE5 KRT18 Homo sapiens P05783
Y2H Prey Pooling
32296183
Intra KRT79 Q5XKE5 KRT27 Homo sapiens Q7Z3Y8
Validated Y2H
32296183
Intra KRT79 Q5XKE5 KRT27 Homo sapiens Q7Z3Y8
Y2H Prey Pooling
32296183
Intra KRT79 Q5XKE5 KRT27 Homo sapiens Q7Z3Y8
Complementation
32296183
Intra KRT79 Q5XKE5 KRT27 Homo sapiens Q7Z3Y8
Y2H Array
32296183
Intra KRT79 Q5XKE5 KRT16 Homo sapiens P08779
Y2H Prey Pooling
32296183
Intra KRT79 Q5XKE5 KRT16 Homo sapiens P08779
Y2H Array
32296183
Intra KRT79 Q5XKE5 KRT14 Homo sapiens P02533
Y2H Prey Pooling
32296183
Intra KRT79 Q5XKE5 KRT14 Homo sapiens P02533
Y2H Array
32296183
Intra KRT79 Q5XKE5 KRT15 Homo sapiens P19012
Validated Y2H
25416956
Intra KRT79 Q5XKE5 KRT15 Homo sapiens P19012
Y2H Prey Pooling
32296183
Intra KRT79 Q5XKE5 KRT15 Homo sapiens P19012
Y2H Array
32296183
Intra KRT79 Q5XKE5 KRT15 Homo sapiens P19012
Y2H Prey Pooling
25416956
Intra KRT79 Q5XKE5 USHBP1 Homo sapiens Q8N6Y0
Y2H Array
25416956
Intra KRT79 Q5XKE5 KRT19 Homo sapiens P08727
Y2H Array
32296183
Intra KRT79 Q5XKE5 KRT19 Homo sapiens P08727
Y2H Prey Pooling
32296183
Intra KRT79 Q5XKE5 EVI5L Homo sapiens Q96CN4
Y2H Prey Pooling
32296183
Intra KRT79 Q5XKE5 EVI5L Homo sapiens Q96CN4
Y2H Array
32296183
Intra KRT79 Q5XKE5 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra KRT79 Q5XKE5 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra KRT79 Q5XKE5 KRT31 Homo sapiens Q15323
Validated Y2H
25416956
Intra KRT79 Q5XKE5 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta KRT79 VGNC VGNC:74150
Rattus norvegicus KRT79 RGD RGD:1583372
Felis catus KRT79 VGNC VGNC:63173
Bos taurus KRT79 VGNC VGNC:30741
Mus musculus KRT79 MGD MGI:2385030
Canis familiaris KRT79 VGNC VGNC:42533