CCL4L1 - C-C motif chemokine ligand 4 like 1 Gene

中文名称：CC 基序趋化因子配体 4 样 1

种属: Homo sapiens

同用名: LAG1; CCL4L; LAG-1; SCYA4L; AT744.2; SCYA4L1; SCYA4L2; MIP-1-beta

关于 CCL4L1

功能概要

该基因是聚集在 17 号染色体 q 臂上的几个细胞因子基因之一。细胞因子是一个分泌蛋白家族，在炎症和免疫调节过程中发挥作用。该家族成员编码的蛋白质类似于趋化因子 (CC 基序) 配体 4 产物，它通过与细胞受体 CCR5 结合来抑制 HIV 进入。该基因的拷贝数因人而异，大多数人有 1 到 5 个拷贝。该基因的可变剪接导致多个转录变体。[RefSeq 提供，2014 年 4 月]

This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this family member is similar to the chemokine (C-C motif) ligand 4 product, which inhibits HIV entry by binding to the cellular receptor CCR5. The copy number of this gene varies among individuals, where most individuals have one to five copies. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]