2. Gene
  3. ERBB2 - erb-b2 receptor tyrosine kinase 2 Gene

ERBB2 - erb-b2 receptor tyrosine kinase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：erb-b2 受体酪氨酸激酶2

种属: Canis lupus familiaris (sub-species: familiaris)

同用名: HER-2; c-erbB-2; p185erbB2

基因 ID: 403883 | 基因类型: protein coding

关于 ERBB2

Primary_assembly 9: 23,553,919-23,606,691 reverse strand.ROS_Cfam_1.0:CM025108.1

This gene has 5 transcripts (splice variants), 200 orthologues and 54 paralogues.

ERBB2 基因产物(1)

mRNA Protein Name
NM_001003217.3 NP_001003217.3 receptor tyrosine-protein kinase erbB-2 precursor

ERBB2 蛋白结构

Recep_L_domain

Recep_L_domain: pfam01030 (51 - 172)

Furin-like

Furin-like: pfam00757 (188 - 337)

Recep_L_domain

Recep_L_domain: pfam01030 (365 - 481)

GF_recep_IV

GF_recep_IV: pfam14843 (510 - 642)

TM_ErbB2

TM_ErbB2: cd12094 (640 - 683)

PTKc_HER2

PTKc_HER2: cd05109 (711 - 989)

  • 0
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  • 1000
  • 1200
  • 1268 a.a.
蛋白主名 其他名称

receptor tyrosine-protein kinase erbB-2

proto-oncogene c-ErbB-2

v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog

重组 ERBB2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74897 HER2/CD340 Protein, Canine (HEK293, His) A0A8I3NJW9 (T23-T652) ≥95%

相关产品

Approval
生物活性分子 (5)
目录号 产品名 作用方式
纯度 是否罕见病
HY-50898 Lapatinib 99.83% 是
HY-13272 Dacomitinib 99.74% 是
HY-50898A Lapatinib ditosylate 99.98% 是
HY-50898B Lapatinib ditosylate monohydrate 99.93% 是
HY-50898C Lapatinib tosylate / 否
Clinical Phase
生物活性分子 (12)
目录号 产品名 作用方式
纯度 Phase
HY-13314 Tesevatinib Inhibitor 99.21% Phase 3
HY-16069A Tucatinib hemiethanolate Inhibitor 99.97% Phase 3
HY-13050 Sapitinib Inhibitor 99.93% Phase 2
HY-10367 Canertinib Inhibitor 99.82% Phase 2
HY-32718 Pelitinib Inhibitor 98.80% Phase 2
HY-10045 AEE788 99.13% Phase 2
HY-10367A Canertinib dihydrochloride Inhibitor 99.68% Phase 2
HY-10322 Falnidamol Inhibitor 99.05% Phase 1
HY-103443 HKI-357 Inhibitor 99.65% Phase 1
HY-10346A AV-412 free base Inhibitor 98.33% Phase 1
HY-116437 Selatinib Inhibitor 99.83% Phase 1
HY-10346 AV-412 Inhibitor 99.17% Phase 1
Pre-clinical Phase
生物活性分子 (38)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-13896 PD168393 98.58% 否
HY-14674 CP-724714 98.53% 否
HY-18609 PD158780 Inhibitor 99.56% 否
HY-15844 AG-825 98.02% 否
HY-13427 Allitinib tosylate Inhibitor 99.83% 否
HY-20878 Tyrphostin AG 879 99.85% 否
HY-135366 HPN-01 Inhibitor 98.61% 否
HY-N1166 Tephrosin 98.02% 否
HY-W006886 Fmoc-(R)-2-(7-octenyl)Ala-OH / 否
HY-103440 EGFR/ErbB-2/ErbB-4 inhibitor-3 Inhibitor 98.19% 否
HY-150023 BI-1622 Inhibitor 98.97% 否
HY-100499 Tyrphostin AG 528 Inhibitor ≥98.0% 否
HY-101042 AG-494 Inhibitor 99.31% 否
HY-112420 EGFR/ErbB-2/ErbB-4 inhibitor-2 Inhibitor 99.45% 否
HY-103441 JNJ28871063 hydrochloride Inhibitor 98.36% 否
HY-50898S Lapatinib-d4 99.02% 否
HY-103439 GW583340 dihydrochloride Inhibitor / 否
HY-13272S2 Dacomitinib-d10 dihydrochloride ≥95.0% 否
HY-15375 Allitinib Inhibitor 99.36% 否
HY-147407 Imbotolimod / 否
HY-123035 Gamendazole Inhibitor / 否
HY-13050A Sapitinib fumarate Inhibitor / 否
HY-13272S3 Dacomitinib-d10 / 否
HY-137028 2′-Thioadenosine Inhibitor / 否
HY-156639 EGFR/ErbB-2 inhibitor-1 Inhibitor / 否
HY-160068 2-2(t) aptamer sodium Chemical / 否
HY-168577 KRAS G12D inhibitor 25 Inhibitor / 否
HY-50898S1 Lapatinib-d7 dihydrochloride / 否
HY-50898S2 Lapatinib-d5 / 否
HY-50898S3 Lapatinib-d4-1 / 否
HY-P4082 ErbB-2-binding peptide 99.83% 否
HY-RS04466 ERBB2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS04467 Erbb2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS04468 ERBB2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-W008914 (E/Z)-CP-724714 Inhibitor / 否
HY-103443A HKI-357 dimaleate Inhibitor / 否
HY-129288 GW837016X Inhibitor / 否
HY-164548 WK88-1 / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P99558 Timigutuzumab Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens ERBB2 NCBI NCBI:2064
Macaca fascicularis ERBB2 NCBI NCBI:102146608
Mus musculus ERBB2 NCBI NCBI:13866
Rattus norvegicus ERBB2 NCBI NCBI:24337
Macaca mulatta ERBB2 NCBI NCBI:697573
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