MPP3 - MAGUK p55 scaffold protein 3 Gene

中文名称：MAGUK p55 支架蛋白 3

种属: Homo sapiens

同用名: DLG3

关于 MPP3

功能概要

该基因产物是称为 MAGUK (膜相关鸟苷酸激酶同系物) 的膜相关蛋白家族的成员。 MAGUK 与细胞骨架相互作用并调节细胞增殖、信号通路和细胞内连接。这种蛋白质包含一个保守序列，称为 SH3 (Src 同源性 3) 基序，在其他几种与细胞骨架相关的蛋白质中发现，并被怀疑在信号转导中发挥重要作用。已经鉴定出可变剪接的转录物变体。实验支持一种转录变体，但它不编码蛋白质。[RefSeq 提供，2008 年 7 月]

This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the Cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (Src homology 3) motif, found in several other proteins that associate with the Cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn't encode a protein. [provided by RefSeq, Jul 2008]