Mapk9 - mitogen-activated protein kinase 9 Gene

中文名称：丝裂原活化蛋白激酶 9

种属: Rattus norvegicus

同用名: SAPK

关于 Mapk9

功能概要

该基因编码的蛋白质是 MAP 激酶家族的成员。 MAP 激酶是多功能蛋白质。它们参与多种细胞过程，例如生长、增殖、分化、转录调节和发育。它们在应激反应、细胞凋亡、炎症和转化中起作用。例如，这种激酶在介导肺癌和前列腺癌细胞增殖以及调节渗透压诱导的紧密连接破坏中起着主导作用。已经报道了几种编码不同亚型的可变剪接转录物变体。 [RefSeq 提供，2012 年 7 月]

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases are multifunctional proteins. They are involved in a wide variety of cellular processes such as growth, proliferation, differentiation, transcription regulation, and development. They function in stress responses, Apoptosis, inflammation and transformation. For example, this kinase plays a dominant role in mediating proliferation of lung Cancer and prostate Cancer cells, and in regulation of osmotic stress-induced tight junction disruption. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2012]