1. Gene
  2. Inpp5d - inositol polyphosphate-5-phosphatase D Gene

Inpp5d - inositol polyphosphate-5-phosphatase D Gene

种属: Rattus norvegicus

基因 ID: 54259 | 基因类型: protein coding

关于 Inpp5d

功能概要

Enables inositol-4,5-bisphosphate 5-phosphatase activity. Predicted to be involved in apoptotic process and phosphatidylinositol dephosphorylation. Predicted to act upstream of or within several processes, including negative regulation of B cell proliferation; negative regulation of bone resorption; and regulation of hemopoiesis. Located in actin filament; cortical cytoskeleton; and cytosol. Colocalizes with plasma membrane. Orthologous to human INPP5D (inositol polyphosphate-5-phosphatase D). [provided by Alliance of Genome Resources, Apr 2022]

Inpp5d 基因产物(1)

mRNA Protein Name
NM_019311.2 NP_062184.2 phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables inositol-4,5-bisphosphate 5-phosphatase activity IDA
IDA: 通过直接分析推断
11714805 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
15661894 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin filament IDA
IDA: 通过直接分析推断
15661894 RGD
located in cortical cytoskeleton IDA
IDA: 通过直接分析推断
15661894 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

Inositol polyphosphate-5-phosphatase, 145 kDa

SH2 domain-containing inositol 5'-phosphatase 1

SH2 domain-containing inositol phosphatase 1

SHIP-1

phosphatidylinositol-4,5-bisphosphate 5-phosphatase

Inpp5d 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Inpp5d P97573 TRIP10 Homo sapiens Q15642-1
Pull Down
26751515
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Inpp5d NCBI NCBI:3635