1. Gene
  2. MIER2 - MIER family member 2 Gene

MIER2 - MIER family member 2 Gene

中文名称:MIER 家族成员 2

种属: Homo sapiens

同用名: Mi-er2; KIAA1193

基因 ID: 54531 | 基因类型: protein coding

关于 MIER2

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:305,573-344,796 (from NCBI)

This gene has 7 transcripts (splice variants), 183 orthologues and 5 paralogues. Broad expression in testis (RPKM 6.0), spleen (RPKM 3.4) and 25 other tissues.

功能概要

启用组蛋白脱乙酰酶结合活性。有助于组蛋白脱乙酰酶活性。参与组蛋白去乙酰化。位于细胞质和细胞核中。部分含蛋白质复合物。 [由基因组资源联盟提供,2022 年 4 月]

Enables histone deacetylase binding activity. Contributes to histone deacetylase activity. Involved in histone deacetylation. Located in cytoplasm and nucleus. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

MIER2 基因产物(8)

mRNA Protein Name
NM_001346105.2 NP_001333034.1 mesoderm induction early response protein 2 isoform 2
NM_001387152.1 NP_001374081.1 mesoderm induction early response protein 2 isoform 3
NM_001387153.1 NP_001374082.1 mesoderm induction early response protein 2 isoform 4
NM_001387154.1 NP_001374083.1 mesoderm induction early response protein 2 isoform 5
NM_001387155.1 NP_001374084.1 mesoderm induction early response protein 2 isoform 2
NM_001387156.1 NP_001374085.1 mesoderm induction early response protein 2 isoform 6
NM_001387157.1 NP_001374086.1 mesoderm induction early response protein 2 isoform 6
NM_017550.3 NP_060020.1 mesoderm induction early response protein 2 isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
contributes to histone deacetylase activity IDA
IDA: 通过直接分析推断
28046085 GOA
enables histone deacetylase binding IPI
IPI: 通过物理相互作用推断
28046085 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
28046085 GOA
located in nucleus IDA
IDA: 通过直接分析推断
28046085 GOA
part of protein-containing complex IDA
IDA: 通过直接分析推断
28046085 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

MIER2 蛋白结构

ELM2

ELM2: ELM2 domain (197 - 248)

  • 0
  • 100
  • 200
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  • 400
  • 500
  • 545 a.a.
蛋白主名 其他名称

mesoderm induction early response protein 2

mesoderm induction early response 1, family member 2

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus MIER2 RGD RGD:1307278
Macaca mulatta MIER2 VGNC VGNC:74855
Mus musculus MIER2 MGD MGI:1917677
Felis catus MIER2 VGNC VGNC:63501
Canis familiaris MIER2 VGNC VGNC:43230
Bos taurus MIER2 VGNC VGNC:31470