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  2. PPP1R7 - protein phosphatase 1 regulatory subunit 7 Gene

PPP1R7 - protein phosphatase 1 regulatory subunit 7 Gene

中文名称:蛋白磷酸酶 1 调节亚基 7

种属: Homo sapiens

同用名: SDS22

基因 ID: 5510 | 基因类型: protein coding

关于 PPP1R7

Cytogenetic location: 2q37.3 Genomic coordinates (GRCh38): 2:241,149,573-241,183,652 (from NCBI)

This gene has 20 transcripts (splice variants), 113 orthologues and 10 paralogues. Broad expression in testis (RPKM 40.9), brain (RPKM 18.7) and 25 other tissues.

功能概要

该基因编码的蛋白质亚基可调节丝氨酸/苏氨酸磷酸酶、蛋白磷酸酶-1 的活性。编码的蛋白质是完成有丝分裂周期和将蛋白磷酸酶-1 靶向有丝分裂动粒所必需的。交替剪接导致多个转录本变体。[RefSeq 提供,2013 年 9 月]

This gene encodes a protein subunit that regulates the activity of the serine/threonine Phosphatase, protein phosphatase-1. The encoded protein is required for completion of the mitotic cycle and for targeting protein phosphatase-1 to mitotic kinetochores. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

PPP1R7 基因产物(7)

mRNA Protein Name
NM_001282409.1 NP_001269338.1 protein phosphatase 1 regulatory subunit 7 isoform 2
NM_001282410.1 NP_001269339.1 protein phosphatase 1 regulatory subunit 7 isoform 3
NM_001282411.1 NP_001269340.1 protein phosphatase 1 regulatory subunit 7 isoform 4
NM_001282412.1 NP_001269341.1 protein phosphatase 1 regulatory subunit 7 isoform 5
NM_001282413.1 NP_001269342.1 protein phosphatase 1 regulatory subunit 7 isoform 6
NM_001282414.1 NP_001269343.1 protein phosphatase 1 regulatory subunit 7 isoform 7
NM_002712.3 NP_002703.1 protein phosphatase 1 regulatory subunit 7 isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
23414517 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromosome IDA
IDA: 通过直接分析推断
22801782 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

PPP1R7 蛋白结构

LRR_9

LRR_9: Leucine-rich repeat (123 - 213)

LRR_4

LRR_4: Leucine Rich repeats (2 copies) (230 - 272)

LRR_4

LRR_4: Leucine Rich repeats (2 copies) (275 - 315)

  • 0
  • 100
  • 200
  • 300
  • 360 a.a.
蛋白主名 其他名称

protein phosphatase 1 regulatory subunit 7

protein phosphatase 1 regulatory subunit 22

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta PPP1R7 VGNC VGNC:99395
Felis catus PPP1R7 VGNC VGNC:80318
Rattus norvegicus PPP1R7 RGD RGD:1308169
Bos taurus PPP1R7 VGNC VGNC:52808
Canis familiaris PPP1R7 VGNC VGNC:59089
Mus musculus PPP1R7 MGD MGI:1913635
Others PPP1R7 NCBI