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  2. PPP1R7 - protein phosphatase 1 regulatory subunit 7 Gene

PPP1R7 - protein phosphatase 1 regulatory subunit 7 Gene

中文名称:蛋白磷酸酶 1 调节亚基 7

种属: Homo sapiens

同用名: SDS22

基因 ID: 5510 | 基因类型: protein coding

关于 PPP1R7

Cytogenetic location: 2q37.3 Genomic coordinates (GRCh38): 2:241,149,573-241,183,652 (from NCBI)

This gene has 20 transcripts (splice variants), 113 orthologues and 10 paralogues. Broad expression in testis (RPKM 40.9), brain (RPKM 18.7) and 25 other tissues.

功能概要

该基因编码的蛋白质亚基可调节丝氨酸/苏氨酸磷酸酶、蛋白磷酸酶-1 的活性。编码的蛋白质是完成有丝分裂周期和将蛋白磷酸酶-1 靶向有丝分裂动粒所必需的。交替剪接导致多个转录本变体。[RefSeq 提供,2013 年 9 月]

This gene encodes a protein subunit that regulates the activity of the serine/threonine Phosphatase, protein phosphatase-1. The encoded protein is required for completion of the mitotic cycle and for targeting protein phosphatase-1 to mitotic kinetochores. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

PPP1R7 基因产物(7)

mRNA Protein Name
NM_001282409.1 NP_001269338.1 protein phosphatase 1 regulatory subunit 7 isoform 2
NM_001282410.1 NP_001269339.1 protein phosphatase 1 regulatory subunit 7 isoform 3
NM_001282411.1 NP_001269340.1 protein phosphatase 1 regulatory subunit 7 isoform 4
NM_001282412.1 NP_001269341.1 protein phosphatase 1 regulatory subunit 7 isoform 5
NM_001282413.1 NP_001269342.1 protein phosphatase 1 regulatory subunit 7 isoform 6
NM_001282414.1 NP_001269343.1 protein phosphatase 1 regulatory subunit 7 isoform 7
NM_002712.3 NP_002703.1 protein phosphatase 1 regulatory subunit 7 isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
23414517 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromosome IDA
IDA: 通过直接分析推断
22801782 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

PPP1R7 蛋白结构

LRR_9

LRR_9: Leucine-rich repeat (123 - 213)

LRR_4

LRR_4: Leucine Rich repeats (2 copies) (230 - 272)

LRR_4

LRR_4: Leucine Rich repeats (2 copies) (275 - 315)

  • 0
  • 100
  • 200
  • 300
  • 360 a.a.
蛋白主名 其他名称

protein phosphatase 1 regulatory subunit 7

protein phosphatase 1 regulatory subunit 22

PPP1R7 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
PPP1R7 Q15435 PPP1CB Homo sapiens P62140 32296183
种属内
PPP1R7 Q15435 PPP1CB Homo sapiens P62140 23414517
种属内
PPP1R7 Q15435 PPP1CB Homo sapiens P62140 32296183
种属内
PPP1R7 Q15435 PPP1CB Homo sapiens P62140
TAP
27173435
种属内
PPP1R7 Q15435 PPP1CC Homo sapiens P36873 33961781
种属内
PPP1R7 Q15435 PPP1CC Homo sapiens P36873
TAP
27173435
种属内
PPP1R7 Q15435 PPP1CA Homo sapiens P62136 33961781
种属内
PPP1R7 Q15435 PPP1CA Homo sapiens P62136
TAP
27173435
种属内
PPP1R7 Q15435 PPP1CA Homo sapiens P62136 28514442
种属内
PPP1R7 Q15435 USHBP1 Homo sapiens Q8N6Y0 25416956
种属内
PPP1R7 Q15435 USHBP1 Homo sapiens Q8N6Y0 25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta PPP1R7 VGNC VGNC:99395
Felis catus PPP1R7 VGNC VGNC:80318
Rattus norvegicus PPP1R7 RGD RGD:1308169
Bos taurus PPP1R7 VGNC VGNC:52808
Canis familiaris PPP1R7 VGNC VGNC:59089
Mus musculus PPP1R7 MGD MGI:1913635
Others PPP1R7 NCBI