2. Gene
  3. PARVA - parvin alpha Gene

PARVA - parvin alpha Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：帕文阿尔法

种属: Homo sapiens

同用名: MXRA2; CH-ILKBP

基因 ID: 55742 | 基因类型: protein coding

关于 PARVA

Cytogenetic location: 11p15.3 Genomic coordinates (GRCh38): 11:12,376,436-12,535,356 (from NCBI)

This gene has 6 transcripts (splice variants), 229 orthologues and 2 paralogues. Ubiquitous expression in endometrium (RPKM 30.7), fat (RPKM 26.7) and 24 other tissues.

功能概要

该基因编码肌动蛋白结合蛋白 parvin 家族的一个成员。 Parvins 与焦点接触相关，并包含与肌动蛋白丝结合的钙调蛋白同源域。编码的蛋白质是整合素连接的激酶信号复合物的一部分，在细胞粘附、运动和存活中发挥作用。[RefSeq 提供，2010 年 12 月]

This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival. [provided by RefSeq, Dec 2010]

PARVA 基因产物(1)

mRNA Protein Name
NM_018222.5 NP_060692.3 alpha-parvin

PARVA 蛋白结构

CH

CH: Calponin homology (CH) domain (140 - 241)

CH

CH: Calponin homology (CH) domain (305 - 408)

  • 0
  • 100
  • 200
  • 300
  • 412 a.a.
蛋白主名 其他名称

alpha-parvin

actopaxin

重组 PARVA 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7493 PARVA/alpha-Parvin Protein, Human (His) Q9NVD7-1 (M1-E372) ≥95%
HY-P76535 PARVA/alpha-Parvin Protein, Human (GST) Q9NVD7-1 (M1-E372) ≥95%

关联疾病

疾病名称 别名
Breast Giant Fibroadenoma

Giant Fibroadenoma

Giant Fibroadenoma Of Breast
Focal Segmental Glomerulosclerosis

Familial Idiopathic Steroid-Resistant Nephrotic Syndrome

Focal Glomerulosclerosis

Fsgs

Segmental Glomerulosclerosis

Glomerulosclerosis, Focal Segmental

Fgs

Focal Glomerular Sclerosis

Familial Idiopathic Nephrotic Syndrome

Focal Sclerosis With Hyalinosis

Glomerulosclerosis, Focal

Glomerulosclerosis Focal

Glomerulosclerosis, Segmental, Focal

Focal Segmental Glomerulosclerosis, Not Otherwise Specified
Adams-Oliver Syndrome

Adams Oliver Syndrome

Aos

Congenital Scalp Defects With Distal Limb Reduction Anomalies

Aplasia Cutis Congenita With Terminal Transverse Limb Defects

Congenital Scalp Defects With Distal Limb Anomalies

Limb, Scalp And Skull Defects

Limb Scalp And Skull Defects

Absence Defect Of Limbs, Scalp, And Skull
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10074 PARVA Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta PARVA VGNC VGNC:75605
Mus musculus PARVA MGD MGI:1931144
Felis catus PARVA VGNC VGNC:64045
Canis familiaris PARVA VGNC VGNC:49689
Bos taurus PARVA VGNC VGNC:32589
Rattus norvegicus PARVA RGD RGD:71021
Others PARVA NCBI
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