2. Gene
  3. HHATL - hedgehog acyltransferase like Gene

HHATL - hedgehog acyltransferase like Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：刺猬酰基转移酶样

种属: Homo sapiens

同用名: GUP1; OACT3; C3orf3; MBOAT3; MSTP002

基因 ID: 57467 | 基因类型: protein coding

关于 HHATL

Cytogenetic location: 3p22.1 Genomic coordinates (GRCh38): 3:42,692,663-42,702,798 (from NCBI)

This gene has 12 transcripts (splice variants), 248 orthologues and 1 paralogue. Restricted expression toward heart (RPKM 165.4).

功能概要

预测启用酰基转移酶活性。预计参与 N 端蛋白质棕榈酰化的负调控。位于细胞质的核周区。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable Acyltransferase activity. Predicted to be involved in negative regulation of N-terminal protein palmitoylation. Located in perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

HHATL 基因产物(1)

mRNA Protein Name
NM_020707.4 NP_065758.3 protein-cysteine N-palmitoyltransferase HHAT-like protein
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
11374908 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

HHATL 蛋白结构

MBOAT

MBOAT: MBOAT, membrane-bound O-acyltransferase family (186 - 406)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 504 a.a.
蛋白主名 其他名称

protein-cysteine N-palmitoyltransferase HHAT-like protein

GUP1 glycerol uptake/transporter homolog

HHATL 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
HHATL Q9HCP6 CISD2 Homo sapiens Q8N5K1
Y2H Prey Pooling
32296183
种属内
HHATL Q9HCP6 CISD2 Homo sapiens Q8N5K1
Y2H Array
32296183
种属内
HHATL Q9HCP6 GPX8 Homo sapiens Q8TED1
Y2H Array
32296183
种属内
HHATL Q9HCP6 GPX8 Homo sapiens Q8TED1
Y2H Prey Pooling
32296183
种属内
HHATL Q9HCP6 FNDC9 Homo sapiens Q8TBE3
Y2H Prey Pooling
32296183
种属内
HHATL Q9HCP6 FNDC9 Homo sapiens Q8TBE3
Y2H Array
32296183
种属内
HHATL Q9HCP6 GPR152 Homo sapiens Q8TDT2
Y2H Prey Pooling
32296183
种属内
HHATL Q9HCP6 GPR152 Homo sapiens Q8TDT2
Y2H Array
32296183
种属内
HHATL Q9HCP6 MUC1 Homo sapiens P15941-11
Y2H Prey Pooling
32296183
种属内
HHATL Q9HCP6 MUC1 Homo sapiens P15941-11
Y2H Array
32296183
种属内
HHATL Q9HCP6 CPLX4 Homo sapiens Q7Z7G2
Y2H Array
32296183
种属内
HHATL Q9HCP6 CPLX4 Homo sapiens Q7Z7G2
Y2H Prey Pooling
32296183
种属内
HHATL Q9HCP6 SUSD3 Homo sapiens Q96L08
Y2H Array
32296183
种属内
HHATL Q9HCP6 SUSD3 Homo sapiens Q96L08
Y2H Prey Pooling
32296183
种属内
HHATL Q9HCP6 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
种属内
HHATL Q9HCP6 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
种属内
HHATL Q9HCP6 MILR1 Homo sapiens Q7Z6M3
Y2H Array
32296183
种属内
HHATL Q9HCP6 MILR1 Homo sapiens Q7Z6M3
Y2H Prey Pooling
32296183
种属内
HHATL Q9HCP6 AMIGO1 Homo sapiens Q86WK6
Y2H Prey Pooling
32296183
种属内
HHATL Q9HCP6 AMIGO1 Homo sapiens Q86WK6
Y2H Array
32296183
种属内
HHATL Q9HCP6 FKBP7 Homo sapiens Q9Y680
Y2H Prey Pooling
32296183
种属内
HHATL Q9HCP6 FKBP7 Homo sapiens Q9Y680
Validated Y2H
32296183
种属内
HHATL Q9HCP6 FKBP7 Homo sapiens Q9Y680
Y2H Array
32296183
种属内
HHATL Q9HCP6 PVR Homo sapiens P15151
Y2H Array
32296183
种属内
HHATL Q9HCP6 PVR Homo sapiens P15151
Y2H Prey Pooling
32296183
种属内
HHATL Q9HCP6 TMX2 Homo sapiens Q9Y320
Y2H Prey Pooling
32296183
种属内
HHATL Q9HCP6 TMX2 Homo sapiens Q9Y320
Validated Y2H
32296183
种属内
HHATL Q9HCP6 TMX2 Homo sapiens Q9Y320
Y2H Array
32296183
种属内
HHATL Q9HCP6 ERGIC3 Homo sapiens Q9Y282
Y2H Prey Pooling
32296183
种属内
HHATL Q9HCP6 ERGIC3 Homo sapiens Q9Y282
Validated Y2H
32296183
种属内
HHATL Q9HCP6 ERGIC3 Homo sapiens Q9Y282
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Nemaline Myopathy 8

NEM8

Nemaline Myopathy 8, Autosomal Recessive

Myopathy, Nemaline, Type 8
Cardiomyopathy, Dilated, 1e

Left Ventricular Noncompaction 9

Left Ventricular Noncompaction 5

Dilated Cardiomyopathy 1e

Dilated Cardiomyopathy 1s

CMD1E

Cdcd2

Cardiomyopathy, Dilated, 1y

CMD1Y

Cardiomyopathy, Dilated, 1s

CMD1S

Dilated Cardiomyopathy 1y

Dilated Cardiomyopathy With Conduction Defect 2

Dilated Cardiomyopathy With Conduction Disorder And Arrhythmia

Cardiomyopathy, Dilated, With Conduction Disorder And Arrhythmia

Cardiomyopathy, Dilated, With Conduction Defect 2

Cardiomyopathy Dilated With Conduction Defect Type 2

Cardiomyopathy, Dilated 1e

Cardiomyopathy, Dilated 1s

Cardiomyopathy, Dilated 1y

Left Ventricular Non-Compaction 5

LVNC5

Left Ventricular Non-Compaction 9

LVNC9

Cardiomyopathy, Dilated, Type 1e

Cardiomyopathy, Dilated, Type 1s

Cardiomyopathy, Dilated, Type 1y
Polycystic Kidney Disease 2 With Or Without Polycystic Liver Disease

Polycystic Kidney Disease 2

PKD2

Polycystic Kidney Disease, Adult, Type Ii

Apkd2

Polycystic Kidney Disease, Type 2

Adpkd2

Adult Polycystic Kidney Disease Type 2

Autosomal Dominant Polycystic Kidney Disease 2

Pkd-2

Polycystic Kidney Disease Adult Type Ii

Polycystic Kidney Type 2 Autosomal Dominant Disease

Kidney Disease, Polycystic, Type 2
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06158 HHATL Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus HHATL VGNC VGNC:29838
Macaca mulatta HHATL VGNC VGNC:73161
Canis familiaris HHATL VGNC VGNC:49672
Felis catus HHATL VGNC VGNC:62808
Rattus norvegicus HHATL RGD RGD:1311911
Mus musculus HHATL MGD MGI:1922020
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