1. Gene
  2. CALCOCO1 - calcium binding and coiled-coil domain 1 Gene

CALCOCO1 - calcium binding and coiled-coil domain 1 Gene

中文名称:钙结合和卷曲螺旋结构域 1

种属: Homo sapiens

同用名: Cocoa; PP13275; calphoglin

基因 ID: 57658 | 基因类型: protein coding

关于 CALCOCO1

This gene has 22 transcripts (splice variants), 256 orthologues and 2 paralogues. Ubiquitous expression in skin (RPKM 52.1), lung (RPKM 44.3) and 25 other tissues.

功能概要

启用多种功能,包括犰狳重复域绑定活动;连环蛋白结合活性;和核受体共激活因子活性。参与基因表达的正调控和转录的正调控,以 DNA 为模板。位于细胞质和细胞核中。 [由基因组资源联盟提供,2022 年 4 月]

Enables several functions, including armadillo repeat domain binding activity; beta-catenin binding activity; and nuclear receptor coactivator activity. Involved in positive regulation of gene expression and positive regulation of transcription, DNA-templated. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

CALCOCO1 基因产物(2)

mRNA Protein Name
NM_001143682.2 NP_001137154.1 calcium-binding and coiled-coil domain-containing protein 1 isoform 2
NM_020898.3 NP_065949.1 calcium-binding and coiled-coil domain-containing protein 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
24245781 GOA
enables beta-catenin binding IPI
IPI: 通过物理相互作用推断
16344550 GOA
enables nuclear receptor coactivator activity IDA
IDA: 通过直接分析推断
16344550 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
16344550 GOA
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
16344550 GOA
enables transcription coactivator activity IMP
IMP: 通过突变表型推断
16344550 GOA
enables transcription coregulator activity IDA
IDA: 通过直接分析推断
16344550 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
16344550 GOA
involved in positive regulation of gene expression IDA
IDA: 通过直接分析推断
16344550 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CALCOCO1 蛋白结构

CALCOCO1

CALCOCO1: Calcium binding and coiled-coil domain (CALCOCO1) like (10 - 596)

  • 0
  • 200
  • 400
  • 600
  • 691 a.a.
蛋白主名 其他名称

calcium-binding and coiled-coil domain-containing protein 1

coiled-coil coactivator protein

CALCOCO1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra CALCOCO1 Q9P1Z2 TBC1D15 Homo sapiens Q8TC07
Validated Y2H
25416956
Intra CALCOCO1 Q9P1Z2 TBC1D15 Homo sapiens Q8TC07
Y2H Array
25416956
Intra CALCOCO1 Q9P1Z2 TBC1D15 Homo sapiens Q8TC07
Y2H Prey Pooling
25416956
Intra CALCOCO1 Q9P1Z2 ISOC1 Homo sapiens Q96CN7
Validated Y2H
25416956
Intra CALCOCO1 Q9P1Z2 ISOC1 Homo sapiens Q96CN7
Y2H Prey Pooling
25416956
Intra CALCOCO1 Q9P1Z2 CWF19L2 Homo sapiens Q2TBE0
Y2H Prey Pooling
25416956
Intra CALCOCO1 Q9P1Z2 CWF19L2 Homo sapiens Q2TBE0
Validated Y2H
25416956
Intra CALCOCO1 Q9P1Z2 NDC80 Homo sapiens O14777
Validated Y2H
25416956
Intra CALCOCO1 Q9P1Z2 GABARAPL2 Homo sapiens P60520
Validated Y2H
25416956
Intra CALCOCO1 Q9P1Z2 CEP19 Homo sapiens Q96LK0
Y2H Prey Pooling
25416956
Intra CALCOCO1 Q9P1Z2 DUSP13B Homo sapiens Q9UII6
Validated Y2H
25416956
Intra CALCOCO1 Q9P1Z2 DUSP13B Homo sapiens Q9UII6
Validated Y2H
32296183
Intra CALCOCO1 Q9P1Z2 DUSP13B Homo sapiens Q9UII6
Y2H Prey Pooling
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Mus musculus CALCOCO1 MGD MGI:1914738
Macaca mulatta CALCOCO1 VGNC VGNC:70668
Felis catus CALCOCO1 VGNC VGNC:60319
Rattus norvegicus CALCOCO1 RGD RGD:619812
Canis familiaris CALCOCO1 VGNC VGNC:38662
Bos taurus CALCOCO1 VGNC VGNC:26702