Nt5e - 5' nucleotidase, ecto Gene

中文名称：5 '核苷酸酶，胞外

种属: Rattus norvegicus

同用名: Nt5; CD73

关于 Nt5e

功能概要

该基因编码的蛋白可启动 5'-核苷酸酶活性和二价铁结合活性。参与多个过程，包括含核碱基的小分子代谢过程；脂质生物合成过程的正调控；和对铝离子的反应。位于细胞表面和突触膜。癫痫持续状态的生物标志物。该基因的人类直系同源物与遗传性动脉和关节多发性钙化综合征有关。与人 NT5E（5'-核苷酸酶外）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables 5'-nucleotidase activity and ferrous iron binding activity. Involved in several processes, including nucleobase-containing small molecule metabolic process; positive regulation of lipid biosynthetic process; and response to aluminum ion. Located in cell surface and synaptic membrane. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in hereditary arterial and articular multiple calcification syndrome. Orthologous to human NT5E (5'-nucleotidase ecto). [provided by Alliance of Genome Resources, Apr 2022]