RPLP0 - ribosomal protein lateral stalk subunit P0 Gene

中文名称：核糖体蛋白侧柄亚基 P0

种属: Homo sapiens

同用名: P0; LP0; L10E; RPP0; PRLP0

关于 RPLP0

功能概要

核糖体是催化蛋白质合成的细胞器，由一个小的 40S 亚基和一个大的 60S 亚基组成。这些亚基一起由 4 种 RNA 和大约 80 种结构不同的蛋白质组成。该基因编码的核糖体蛋白是 60S 亚基的一个组成部分。该蛋白质是大肠杆菌 L10 核糖体蛋白的功能等价物，属于核糖体蛋白 L10P 家族。它是一种中性磷蛋白，其 C 末端与酸性核糖体磷蛋白 P1 和 P2 的 C 末端几乎相同。 P0 蛋白可以与 P1 和 P2 相互作用形成由 P1 和 P2 二聚体以及一个 P0 单体组成的五聚体复合物。该蛋白质位于细胞质中。存在源自可变剪接的转录本变体；它们编码相同的蛋白质。作为典型的编码核糖体蛋白的基因，该基因有多个经过处理的假基因分散在基因组中。[RefSeq 提供，2008 年 7 月]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]