RPS2 - ribosomal protein S2 Gene

中文名称：核糖体蛋白 S2

种属: Homo sapiens

同用名: S2; LLREP3

基因 ID: 6187 | 基因类型: protein coding

关于 RPS2

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:1,962,058-1,964,826 (from NCBI)

This gene has 17 transcripts (splice variants), 141 orthologues and 1 paralogue. Ubiquitous expression in ovary (RPKM 1267.2), bone marrow (RPKM 851.7) and 25 other tissues.

功能概要

核糖体是催化蛋白质合成的细胞器，由一个小的 40S 亚基和一个大的 60S 亚基组成。这些亚基一起由 4 种 RNA 和大约 80 种结构不同的蛋白质组成。该基因编码的核糖体蛋白是 40S 亚基的一个组成部分。该蛋白属于核糖体蛋白的 S5P 家族。它位于细胞质中。该基因与小鼠 LLRep3 具有序列相似性。它与位于其第三个内含子中的小核仁 RNA 基因 U64 共同转录。作为典型的编码核糖体蛋白的基因，该基因有多个经过处理的假基因分散在基因组中。[RefSeq 提供，2008 年 7 月]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S5P family of ribosomal proteins. It is located in the cytoplasm. This gene shares sequence similarity with mouse LLRep3. It is co-transcribed with the small nucleolar RNA gene U64, which is located in its third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

RPS2 基因产物(1)

mRNA	Protein	Name
NM_002952.4	NP_002943.2	40S ribosomal protein S2

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables enzyme binding	IPI IPI: 通过物理相互作用推断	18573314	GOA
enables fibroblast growth factor binding	IPI IPI: 通过物理相互作用推断	16263090	GOA
enables mRNA binding	IDA IDA: 通过直接分析推断	18464793	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	15473865	GOA
enables structural constituent of ribosome	IDA IDA: 通过直接分析推断	23636399	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in positive regulation of ubiquitin-protein transferase activity	IDA IDA: 通过直接分析推断	18573314	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytosolic ribosome	IDA IDA: 通过直接分析推断	23636399	GOA
part of cytosolic small ribosomal subunit	IDA IDA: 通过直接分析推断	8706699	GOA
NOT located in nucleolus	IDA IDA: 通过直接分析推断	16061210	GOA
located in nucleoplasm	IDA IDA: 通过直接分析推断	16061210	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RPS2 蛋白结构

Ribosomal_S5

Ribosomal_S5_C

0
100
200
293 a.a.

蛋白主名

其他名称

40S ribosomal protein S2

40S ribosomal protein S4

RPS2 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	RPS2	P15880	PRMT3	Homo sapiens	O60678	Anti Tag CoIP	33961781
种属内	RPS2	P15880	PRMT3	Homo sapiens	O60678	Anti Tag CoIP	25737013
种属内	RPS2	P15880	PRMT3	Homo sapiens	O60678	Y2H Array	32296183
种属内	RPS2	P15880	PRMT3	Homo sapiens	O60678	Y2H Prey Pooling	32296183
种属内	RPS2	P15880	RPS9	Homo sapiens	P46781	Anti Tag CoIP	33961781
种属内	RPS2	P15880	PDCD2	Homo sapiens	Q16342	Anti Tag CoIP	33961781
种属内	RPS2	P15880	PDCD2	Homo sapiens	Q16342	Anti Tag CoIP	28514442
种属内	RPS2	P15880	NAT10	Homo sapiens	Q9H0A0	Anti Tag CoIP	33961781
种属内	RPS2	P15880	NAT10	Homo sapiens	Q9H0A0	Anti Tag CoIP	28514442

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Retinitis Pigmentosa 36

RP36	Retinitis Pigmentosa-36
Retinitis Pigmentosa, Type 36

Diamond-Blackfan Anemia

Congenital Pure Red Cell Aplasia	Aase Syndrome
Erythrogenesis Imperfecta	Anemia, Diamond-Blackfan
Congenital Hypoplastic Anemia	Aase-Smith Ii Syndrome
Bds	Blackfan-Diamond Anemia
Congenital Prca	Congenital Hypoplastic Anemia, Blackfan-Diamond Type
Dba	Blackfan - Diamond Syndrome
Chronic Constitutional Pure Red Cell Anaemia	Anemia Diamond Blackfan Type
Anemia Congenital Erythroid Hypoplastic	Aregenerative Anemia Chronic Congenital
Blackfan Diamond Syndrome	Red Cell Aplasia, Pure Hereditary
Aase-Smith Syndrome Ii	Bda
Blackfan Diamond Anemia	Blackfan-Diamond Disease
Blackfan-Diamond Syndrome	Chronic Congenital Agenerative Anemia
Congenital Erythroid Hypoplastic Anemia	Congenital Hypoplastic Anemia Of Blackfan And Diamond
Congenital Pure Red Cell Anemia	Hypoplastic Congenital Anemia
Inherited Erythroblastopenia	Pure Hereditary Red Cell Aplasia
Anemia, Hypoplastic, Congenital	Anemia Hypoplastic Congenital
Fanconi Anemia	Constitutional Aplastic Anemia
Diamond-Blackfan Anemia 1	Aase Smith Syndrome 2
Congenital Red Cell Aplasia	Red Cell Aplasia Of Infants
Pure Red Cell Aplasia Of Infants	Congenital Red Cell Aplastic Anaemia
Congenital Pure Red Cell Anaemia	Congenital Erythroid Hypoplasia
Pearson Marrow-Pancreas Syndrome

Retinitis Pigmentosa 20

RP20	Retinitis Pigmentosa, Type 20

Retinitis Pigmentosa 14

RP14	Retinitis Pigmentosa Juvenile Tulp1-Related
Retinitis Pigmentosa-14	Retinitis Pigmentosa, Type 14

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS12231	RPS2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Bos taurus	RPS2	VGNC	VGNC:56750
Mus musculus	RPS2	MGD	MGI:105110
Felis catus	RPS2	VGNC	VGNC:80681
Rattus norvegicus	RPS2	RGD	RGD:619887
Others	RPS2	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

RPS2 - ribosomal protein S2 Gene

关于 RPS2

功能概要

RPS2 基因产物(1)

RPS2 蛋白结构

RPS2 蛋白互作信息

关联疾病

直系同源

热门区域

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RPS2 - ribosomal protein S2 Gene

关于 RPS2

功能概要

RPS2 基因产物(1)

RPS2 蛋白结构

RPS2 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z