2. Gene
  3. RPS7 - ribosomal protein S7 Gene

RPS7 - ribosomal protein S7 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：核糖体蛋白 S7

种属: Homo sapiens

同用名: S7; eS7; DBA8

基因 ID: 6201 | 基因类型: protein coding

关于 RPS7

Cytogenetic location: 2p25.3 Genomic coordinates (GRCh38): 2:3,575,260-3,580,920 (from NCBI)

This gene has 12 transcripts (splice variants), 228 orthologues and is associated with 2 phenotypes. Ubiquitous expression in ovary (RPKM 822.9), bone marrow (RPKM 559.6) and 25 other tissues.

功能概要

核糖体是催化蛋白质合成的细胞器，由一个小的 40S 亚基和一个大的 60S 亚基组成。这些亚基一起由 4 种 RNA 和大约 80 种结构不同的蛋白质组成。该基因编码的核糖体蛋白是 40S 亚基的一个组成部分。该蛋白属于核糖体蛋白的 S7E 家族。它位于细胞质中。作为典型的编码核糖体蛋白的基因，该基因有多个经过处理的假基因分散在基因组中。[RefSeq 提供，2008 年 7 月]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

RPS7 基因产物(1)

mRNA Protein Name
NM_001011.4 NP_001002.1 40S ribosomal protein S7
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mRNA 3'-UTR binding IDA
IDA: 通过直接分析推断
16213212 GOA
enables mRNA 5'-UTR binding IDA
IDA: 通过直接分析推断
16213212 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
9687515 GOA
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
20873783 GOA
enables structural constituent of ribosome IDA
IDA: 通过直接分析推断
23636399 GOA
enables structural constituent of ribosome IMP
IMP: 通过突变表型推断
18697920 GOA
enables ubiquitin ligase inhibitor activity IDA
IDA: 通过直接分析推断
17310983 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of ubiquitin protein ligase activity IDA
IDA: 通过直接分析推断
17310983 GOA
involved in negative regulation of ubiquitin-dependent protein catabolic process IDA
IDA: 通过直接分析推断
17310983 GOA
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
17310983 GOA
involved in positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator IMP
IMP: 通过突变表型推断
17310983 GOA
involved in protein stabilization IMP
IMP: 通过突变表型推断
17310983 GOA
involved in rRNA processing IMP
IMP: 通过突变表型推断
18697920 GOA
involved in ribosomal small subunit biogenesis IDA
IDA: 通过直接分析推断
34516797 GOA
involved in ribosomal small subunit biogenesis IMP
IMP: 通过突变表型推断
18697920 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
colocalizes with centrosome IDA
IDA: 通过直接分析推断
20873783 GOA
located in cytosolic ribosome IDA
IDA: 通过直接分析推断
23636399 GOA
part of cytosolic small ribosomal subunit IDA
IDA: 通过直接分析推断
8706699 GOA
located in nucleolus IDA
IDA: 通过直接分析推断
11823430 GOA
located in nucleus IDA
IDA: 通过直接分析推断
9687515 GOA
part of protein-containing complex IDA
IDA: 通过直接分析推断
20873783 GOA
part of protein-containing complex IMP
IMP: 通过突变表型推断
17310983 GOA
part of ribonucleoprotein complex IDA
IDA: 通过直接分析推断
18809582 GOA
part of small-subunit processome IDA
IDA: 通过直接分析推断
34516797 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RPS7 蛋白结构

Ribosomal_S7e

Ribosomal_S7e: Ribosomal protein S7e (7 - 191)

  • 0
  • 100
  • 194 a.a.
蛋白主名 其他名称

40S ribosomal protein S7

small ribosomal subunit protein eS7

RPS7 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
RPS7 P62081 MDM2 Homo sapiens Q00987
Anti Tag CoIP
33961781
种属内
RPS7 P62081 MDM2 Homo sapiens Q00987
Anti Tag CoIP
17310983
种属内
RPS7 P62081 NEDD8 Homo sapiens Q15843
Pull Down
18274552
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 RPS7 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71266 RPS7 Protein, Human (His) P62081 (M1-L194) ≥95%

关联疾病

疾病名称 别名
Diamond-Blackfan Anemia 8

DBA8

Rps7-Related Diamond-Blackfan Anemia

Anemia, Diamond-Blackfan, Type 8
Diamond-Blackfan Anemia

Congenital Pure Red Cell Aplasia

Aase Syndrome

Erythrogenesis Imperfecta

Anemia, Diamond-Blackfan

Congenital Hypoplastic Anemia

Aase-Smith Ii Syndrome

Bds

Blackfan-Diamond Anemia

Congenital Prca

Congenital Hypoplastic Anemia, Blackfan-Diamond Type

Dba

Blackfan - Diamond Syndrome

Chronic Constitutional Pure Red Cell Anaemia

Anemia Diamond Blackfan Type

Anemia Congenital Erythroid Hypoplastic

Aregenerative Anemia Chronic Congenital

Blackfan Diamond Syndrome

Red Cell Aplasia, Pure Hereditary

Aase-Smith Syndrome Ii

Bda

Blackfan Diamond Anemia

Blackfan-Diamond Disease

Blackfan-Diamond Syndrome

Chronic Congenital Agenerative Anemia

Congenital Erythroid Hypoplastic Anemia

Congenital Hypoplastic Anemia Of Blackfan And Diamond

Congenital Pure Red Cell Anemia

Hypoplastic Congenital Anemia

Inherited Erythroblastopenia

Pure Hereditary Red Cell Aplasia

Anemia, Hypoplastic, Congenital

Anemia Hypoplastic Congenital

Fanconi Anemia

Constitutional Aplastic Anemia

Diamond-Blackfan Anemia 1

Aase Smith Syndrome 2

Congenital Red Cell Aplasia

Red Cell Aplasia Of Infants

Pure Red Cell Aplasia Of Infants

Congenital Red Cell Aplastic Anaemia

Congenital Pure Red Cell Anaemia

Congenital Erythroid Hypoplasia

Pearson Marrow-Pancreas Syndrome
Macrocytic Anemia

Anemia Macrocytic

Anemia, Macrocytic

Macrocytic Anaemia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12269 RPS7 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus RPS7 MGD MGI:1333818
Canis familiaris RPS7 VGNC VGNC:45748
Bos taurus RPS7 VGNC VGNC:34150
Macaca mulatta RPS7 VGNC VGNC:106214
Rattus norvegicus RPS7 RGD RGD:61907
Others RPS7 NCBI
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z