SMAP2 - small ArfGAP2 Gene

中文名称：小 ArfGAP2

种属: Homo sapiens

同用名: SMAP1L

基因 ID: 64744 | 基因类型: protein coding

关于 SMAP2

Cytogenetic location: 1p34.2 Genomic coordinates (GRCh38): 1:40,344,834-40,423,326 (from NCBI)

This gene has 6 transcripts (splice variants), 186 orthologues and 28 paralogues. Broad expression in lymph node (RPKM 80.3), spleen (RPKM 58.9) and 23 other tissues.

功能概要

预测启用 GTPase 激活剂活动。预计参与催化活性的调节。预计位于细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable GTPase activator activity. Predicted to be involved in regulation of catalytic activity. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

SMAP2 基因产物(4)

mRNA	Protein	Name
NM_001198978.2	NP_001185907.1	stromal membrane-associated protein 2 isoform 3
NM_001198979.2	NP_001185908.1	stromal membrane-associated protein 2 isoform 2
NM_001198980.1	NP_001185909.1	stromal membrane-associated protein 2 isoform 4
NM_022733.3	NP_073570.1	stromal membrane-associated protein 2 isoform 1

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	25416956	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SMAP2 蛋白结构

ArfGap

0
100
200
300
400
429 a.a.

蛋白主名

其他名称

stromal membrane-associated protein 2

stromal membrane-associated GTPase-activating protein 2

SMAP2 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	SMAP2	Q8WU79	KRTAP6-2	Homo sapiens	Q3LI66	Y2H Array	32296183
Intra	SMAP2	Q8WU79	KRTAP6-2	Homo sapiens	Q3LI66	Y2H Prey Pooling	32296183
Intra	SMAP2	Q8WU79	SMAP1	Homo sapiens	Q8IYB5-2	Y2H Array	32296183
Intra	SMAP2	Q8WU79	SMAP1	Homo sapiens	Q8IYB5-2	Y2H Prey Pooling	32296183
Intra	SMAP2	Q8WU79	MSX2	Homo sapiens	P35548	Y2H Array	32296183
Intra	SMAP2	Q8WU79	MSX2	Homo sapiens	P35548	Y2H Prey Pooling	32296183
Intra	SMAP2	Q8WU79	BHLHE40	Homo sapiens	O14503	Y2H Array	32296183
Intra	SMAP2	Q8WU79	BHLHE40	Homo sapiens	O14503	Y2H Prey Pooling	32296183
Intra	SMAP2	Q8WU79	MAGED1	Homo sapiens	Q9Y5V3	Y2H Array	25416956
Intra	SMAP2	Q8WU79	MAGED1	Homo sapiens	Q9Y5V3	Y2H Array	32296183
Intra	SMAP2	Q8WU79	MAGED1	Homo sapiens	Q9Y5V3	Validated Y2H	25416956
Intra	SMAP2	Q8WU79	MAGED1	Homo sapiens	Q9Y5V3	Validated Y2H	32296183
Intra	SMAP2	Q8WU79	MAGED1	Homo sapiens	Q9Y5V3	Y2H Prey Pooling	32296183
Intra	SMAP2	Q8WU79	DAZAP2	Homo sapiens	Q15038	Y2H Array	25416956
Intra	SMAP2	Q8WU79	DAZAP2	Homo sapiens	Q15038	Y2H Array	32296183
Intra	SMAP2	Q8WU79	DAZAP2	Homo sapiens	Q15038	Y2H Prey Pooling	25416956
Intra	SMAP2	Q8WU79	DAZAP2	Homo sapiens	Q15038	Validated Y2H	25416956
Intra	SMAP2	Q8WU79	DAZAP2	Homo sapiens	Q15038	Y2H Prey Pooling	32296183
Intra	SMAP2	Q8WU79	CRX	Homo sapiens	O43186	Y2H Prey Pooling	32296183
Intra	SMAP2	Q8WU79	CRX	Homo sapiens	O43186	Y2H Array	32296183
Intra	SMAP2	Q8WU79	TENT5B	Homo sapiens	Q96A09	Validated Y2H	32296183
Intra	SMAP2	Q8WU79	TENT5B	Homo sapiens	Q96A09	Y2H Prey Pooling	32296183
Intra	SMAP2	Q8WU79	TENT5B	Homo sapiens	Q96A09	Y2H Array	32296183
Intra	SMAP2	Q8WU79	DAB1	Homo sapiens	O75553	Y2H Prey Pooling	25416956
Intra	SMAP2	Q8WU79	DAB1	Homo sapiens	O75553	Y2H Array	25416956
Intra	SMAP2	Q8WU79	FAM168A	Homo sapiens	Q92567	Y2H Prey Pooling	25416956
Intra	SMAP2	Q8WU79	C1orf94	Homo sapiens	Q6P1W5	Validated Y2H	25416956

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Spermatogenic Failure 9

Male Infertility Due To Globozoospermia	SPGF9
Male Infertility Due To Round-Headed Spermatozoa	Globozoospermia, Complete
Globozoospermia, Total	Globozoospermia
Globozoospermia Syndrome	Round-Headed Sperm Syndrome
Globozoospermia Complete	Globozoospermia Total

Kniest Dysplasia

Kniest Syndrome	Metatropic Dwarfism, Type Ii
Kniest Chondrodystrophy	Metatropic Dysplasia Type Ii
Swiss Cheese Cartilage Dysplasia	KD
Ks	Metatropic Dwarfism Type Ii
Dysplasia, Kniest

Vitreous Syneresis

Vitreous Degeneration

Multiple Epiphyseal Dysplasia Due To Collagen 9 Anomaly

Marshall Syndrome

MRSHS	Deafness, Myopia, Cataract, Saddle Nose-Marshall Type
Periodic Fever, Aphthous Stomatitis, Pharyngitis And Adenitis	Pfapa Syndrome
Pfapa	Marshall Syndrome With Periodic Fever
Periodic Fever-Aphtous Stomatitis-Pharyngitis-Adenopathy Syndrome

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-120272	SMAP-2	Activator	99.63%	否
HY-RS13402	SMAP2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	SMAP2	VGNC	VGNC:65461
Canis familiaris	SMAP2	VGNC	VGNC:54223
Mus musculus	SMAP2	MGD	MGI:1917030
Macaca mulatta	SMAP2	VGNC	VGNC:77772
Rattus norvegicus	SMAP2	RGD	RGD:1308418
Bos taurus	SMAP2	VGNC	VGNC:34984

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

SMAP2 - small ArfGAP2 Gene

关于 SMAP2

功能概要

SMAP2 基因产物(4)

SMAP2 蛋白结构

SMAP2 蛋白互作信息

关联疾病

直系同源

热门区域

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SMAP2 - small ArfGAP2 Gene

关于 SMAP2

功能概要

SMAP2 基因产物(4)

SMAP2 蛋白结构

SMAP2 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z