1. Gene
  2. FAM168A - family with sequence similarity 168 member A Gene

FAM168A - family with sequence similarity 168 member A Gene

中文名称:具有序列相似性的家族 168 成员 A

种属: Homo sapiens

同用名: TCRP1; KIAA0280

基因 ID: 23201 | 基因类型: protein coding

关于 FAM168A

Cytogenetic location: 11q13.4 Genomic coordinates (GRCh38): 11:73,400,487-73,598,112 (from NCBI)

This gene has 5 transcripts (splice variants), 223 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 45.1), gall bladder (RPKM 10.1) and 24 other tissues.

功能概要

参与碱基切除修复的正调控。 [由基因组资源联盟提供,2022 年 4 月]

Involved in positive regulation of base-excision repair. [provided by Alliance of Genome Resources, Apr 2022]

FAM168A 基因产物(3)

mRNA Protein Name
NM_001286050.2 NP_001272979.1 protein FAM168A isoform 1
NM_001286051.2 NP_001272980.1 protein FAM168A isoform 3
NM_015159.3 NP_055974.1 protein FAM168A isoform 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21516116 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of base-excision repair IDA
IDA: 通过直接分析推断
25260657 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

FAM168A 蛋白结构

TCRP1

TCRP1: Tongue Cancer Chemotherapy Resistant Protein 1 (1 - 244)

  • 0
  • 100
  • 200
  • 244 a.a.
蛋白主名 其他名称

protein FAM168A

tongue cancer chemotherapy resistance-associated protein 1

FAM168A 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra FAM168A Q92567 PRR20C Homo sapiens P86479
Y2H Prey Pooling
25416956
Intra FAM168A Q92567 SNRPC Homo sapiens Q5TAL4
Validated Y2H
25416956
Intra FAM168A Q92567 SNRPC Homo sapiens Q5TAL4
Y2H Array
25416956
Intra FAM168A Q92567 R3HDM2 Homo sapiens Q9Y2K5-2
Y2H Prey Pooling
25416956
Intra FAM168A Q92567 R3HDM2 Homo sapiens Q9Y2K5-2
Validated Y2H
25416956
Intra FAM168A Q92567 UBE2V1 Homo sapiens Q13404
Validated Y2H
25416956
Intra FAM168A Q92567 UBASH3B Homo sapiens Q8TF42
Y2H Array
25416956
Intra FAM168A Q92567 UBASH3B Homo sapiens Q8TF42
Y2H Prey Pooling
25416956
Intra FAM168A Q92567 UBASH3B Homo sapiens Q8TF42
Validated Y2H
25416956
Intra FAM168A Q92567 NAF1 Homo sapiens Q96HR8
Validated Y2H
25416956
Intra FAM168A Q92567 NAF1 Homo sapiens Q96HR8
Y2H Array
25416956
Intra FAM168A Q92567 NAF1 Homo sapiens Q96HR8
Y2H Prey Pooling
25416956
Intra FAM168A Q92567 VPS37C Homo sapiens A5D8V6
Validated Y2H
25416956
Intra FAM168A Q92567 SMAP2 Homo sapiens Q8WU79
Validated Y2H
25416956
Intra FAM168A Q92567 SMAP2 Homo sapiens Q8WU79
Y2H Array
25416956
Intra FAM168A Q92567 TAX1BP1 Homo sapiens Q86VP1
Validated Y2H
25416956
Intra FAM168A Q92567 DAZAP2 Homo sapiens Q15038
Y2H Array
25416956
Intra FAM168A Q92567 KLHL42 Homo sapiens Q9P2K6
Y2H Prey Pooling
25416956
Intra FAM168A Q92567 RBPMS Homo sapiens Q93062
Validated Y2H
25416956
Intra FAM168A Q92567 RBPMS Homo sapiens Q93062
Y2H Array
25416956
Intra FAM168A Q92567 RBPMS Homo sapiens Q93062
Y2H Prey Pooling
25416956
Intra FAM168A Q92567 DTX2 Homo sapiens Q86UW9
Y2H Prey Pooling
25416956
Intra FAM168A Q92567 DTX2 Homo sapiens Q86UW9
Validated Y2H
25416956
Intra FAM168A Q92567 DTX2 Homo sapiens Q86UW9
Y2H Array
25416956
Intra FAM168A Q92567 SF1 Homo sapiens Q15637
Y2H Prey Pooling
25416956
Intra FAM168A Q92567 SF1 Homo sapiens Q15637
Validated Y2H
25416956
Intra FAM168A Q92567 SF1 Homo sapiens Q15637
Y2H Array
25416956
Intra FAM168A Q92567 SS18L1 Homo sapiens O75177
Y2H Prey Pooling
25416956
Intra FAM168A Q92567 SS18L1 Homo sapiens O75177
Validated Y2H
25416956
Intra FAM168A Q92567 SS18L1 Homo sapiens O75177
Y2H Array
25416956
Intra FAM168A Q92567 OTUB2 Homo sapiens Q96DC9
Y2H Array
31515488
Intra FAM168A Q92567 OTUB2 Homo sapiens Q96DC9
Y2H Array
25416956
Intra FAM168A Q92567 OTULIN Homo sapiens Q96BN8
Validated Y2H
25416956
Intra FAM168A Q92567 DAB1 Homo sapiens O75553
Y2H Prey Pooling
25416956
Intra FAM168A Q92567 DAB1 Homo sapiens O75553
Validated Y2H
25416956
Intra FAM168A Q92567 DAB1 Homo sapiens O75553
Y2H Array
25416956
Intra FAM168A Q92567 C1orf94 Homo sapiens Q6P1W5
Validated Y2H
25416956
Intra FAM168A Q92567 C1orf94 Homo sapiens Q6P1W5
Y2H Array
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Oral Squamous Cell Carcinoma

Mouth Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Mouth

Tongue Carcinoma

Tongue Cancer

Malignant Neoplasm Of Tongue

Tongue Neoplasms

Tongue Neoplasm

Deafness, Autosomal Recessive 63

DFNB63

Autosomal Recessive Nonsyndromic Deafness 63

Autosomal Recessive Deafness 63

Deafness, Autosomal Recessive, 63

Non-Syndromic Neurosensory Deafness Autosomal Recessive Type 63

Non-Syndromic Sensorineural Deafness Autosomal Recessive Type 63

Deafness, Autosomal Recessive, Type 63

Tongue Disease

Abnormality Of The Tongue

Tongue Diseases

Tongue Disorders

Disorder Of Tongue

Glossopathy

Unspecified Condition Of The Tongue

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus FAM168A VGNC VGNC:102881
Mus musculus FAM168A MGD MGI:2442372
Canis familiaris FAM168A VGNC VGNC:40619
Bos taurus FAM168A VGNC VGNC:28752
Rattus norvegicus FAM168A RGD RGD:1308929
Macaca mulatta FAM168A VGNC VGNC:72398