1. Gene
  2. Ace2 - angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 Gene

Ace2 - angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 Gene

种属: Mus musculus

同用名: 2010305L05Rik

基因 ID: 70008 | 基因类型: protein coding

关于 Ace2

功能概要

Predicted to enable identical protein binding activity; peptidase activity; and virus receptor activity. Involved in positive regulation of cardiac muscle contraction and tryptophan transport. Located in brush border membrane and cytoplasm. Is expressed in several structures, including brain; cardiovascular system; extraembryonic component; genitourinary system; and respiratory system. Used to study COVID-19 and congestive heart failure. Human ortholog(s) of this gene implicated in several diseases, including avian influenza; cerebral malaria; hypertension (multiple); respiratory syncytial virus infectious disease; and severe acute respiratory syndrome. Orthologous to human ACE2 (angiotensin converting Enzyme 2). [provided by Alliance of Genome Resources, Apr 2022]

Ace2 基因产物(2)

mRNA Protein Name
NM_001130513.1 NP_001123985.1 angiotensin-converting enzyme 2 precursor
NM_027286.4 NP_081562.2 angiotensin-converting enzyme 2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19185582 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of cardiac muscle contraction IMP
IMP: 通过突变表型推断
12075344 MGI
involved in tryptophan transport IMP
IMP: 通过突变表型推断
22837003 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in brush border membrane IDA
IDA: 通过直接分析推断
19185582 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
23535237 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
23535237 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

angiotensin-converting enzyme 2

ACE-related carboxypeptidase

angiotensin I converting enzyme 2

重组 Ace2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74433 ACE2 Protein, Mouse (HEK293, His-Fc) Q8R0I0-1 (Q18-T740) ≥95%
HY-P74434 ACE2 Protein, Mouse (HEK293, His) Q8R0I0-1 (Q18-T740) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ace2 NCBI NCBI:59272
Macaca fascicularis Ace2 NCBI NCBI:102130864
Rattus norvegicus Ace2 NCBI NCBI:302668
Macaca mulatta Ace2 NCBI NCBI:712790