1. Gene
  2. XBP1 - X-box binding protein 1 Gene

XBP1 - X-box binding protein 1 Gene

中文名称:X-box 结合蛋白 1

种属: Homo sapiens

同用名: XBP2; TREB5; XBP-1; TREB-5

基因 ID: 7494 | 基因类型: protein coding

关于 XBP1

Cytogenetic location: 22q12.1 Genomic coordinates (GRCh38): 22:28,794,560-28,800,569 (from NCBI)

This gene has 6 transcripts (splice variants), 197 orthologues and is associated with 1 phenotype. Ubiquitous expression in salivary gland (RPKM 196.1), urinary bladder (RPKM 191.7) and 25 other tissues.

功能概要

该基因编码的转录因子通过与称为 X 盒的启动子元件结合来调节 MHC II 类基因。该基因产物是一种 bZIP 蛋白,也被鉴定为一种细胞转录因子,可与 T 细胞白血病病毒 1 型启动子中的增强子结合。它可以通过充当病毒反式激活因子的 DNA 结合伴侣来增加病毒蛋白的表达。已经发现,在内质网 (ER) 中积累未折叠的蛋白质后,该基因的 mRNA 通过需要肌醇内切酶 1 (IRE1) 介导的非常规剪接机制加工成活性形式。剪接的 mRNA 中 26 nt 的损失会导致移码和亚型 XBP1 (S) ,这是功能活跃的转录因子。由未剪接的 mRNA XBP1 (U) 编码的亚型组成型表达,并被认为作为 XBP1 (S) 的负反馈调节剂起作用,它在 ER 应激的恢复阶段关闭靶基因的转录。 XBP1 的假基因已被识别并定位于 5 号染色体。[RefSeq 提供,2008 年 7 月]

This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of Viral Proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the Endonuclease inositol-requiring Enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress. A pseudogene of XBP1 has been identified and localized to chromosome 5. [provided by RefSeq, Jul 2008]

XBP1 基因产物(4)

mRNA Protein Name
NM_001079539.2 NP_001073007.1 X-box-binding protein 1 isoform XBP1(S)
NM_001393999.1 NP_001380928.1 X-box-binding protein 1 isoform 3
NM_001394000.1 NP_001380929.1 X-box-binding protein 1 isoform 4
NM_005080.4 NP_005071.2 X-box-binding protein 1 isoform XBP1(U)
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
1903538 GOA
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
11779464 GOA
enables chromatin DNA binding IDA
IDA: 通过直接分析推断
25280941 GOA
enables cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
2196176 GOA
enables identical protein binding IPI
IPI: 通过物理相互作用推断
20102225 GOA
enables protease binding IPI
IPI: 通过物理相互作用推断
25239945 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
16461360 GOA
enables protein heterodimerization activity IDA
IDA: 通过直接分析推断
1903538 GOA
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
20348923 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: 通过直接分析推断
28473536 GOA
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
23184933 GOA
enables ubiquitin protein ligase binding IPI
IPI: 通过物理相互作用推断
25239945 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to fluid shear stress IDA
IDA: 通过直接分析推断
25190803 GOA
involved in cellular response to laminar fluid shear stress IDA
IDA: 通过直接分析推断
25280941 GOA
involved in cellular response to lipopolysaccharide IDA
IDA: 通过直接分析推断
11460154 GOA
involved in cellular response to oxidative stress IDA
IDA: 通过直接分析推断
25190803 GOA
involved in cellular response to vascular endothelial growth factor stimulus IDA
IDA: 通过直接分析推断
23529610 GOA
involved in endoplasmic reticulum unfolded protein response IDA
IDA: 通过直接分析推断
25239945 GOA
involved in endothelial cell proliferation IDA
IDA: 通过直接分析推断
23529610 GOA
involved in negative regulation of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
26315405 GOA
involved in negative regulation of SMAD protein signal transduction IDA
IDA: 通过直接分析推断
26315405 GOA
involved in negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IDA
IDA: 通过直接分析推断
19135031 GOA
involved in negative regulation of endoplasmic reticulum unfolded protein response IDA
IDA: 通过直接分析推断
25239945 GOA
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
16461360 GOA
involved in negative regulation of transforming growth factor beta receptor signaling pathway IDA
IDA: 通过直接分析推断
26315405 GOA
involved in phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: 通过直接分析推断
23529610 GOA
involved in positive regulation of B cell differentiation IDA
IDA: 通过直接分析推断
11460154 GOA
involved in positive regulation of MHC class II biosynthetic process IMP
IMP: 通过突变表型推断
1903538 GOA
involved in positive regulation of T cell differentiation IDA
IDA: 通过直接分析推断
11460154 GOA
involved in positive regulation of TOR signaling IMP
IMP: 通过突变表型推断
25190803 GOA
involved in positive regulation of angiogenesis IMP
IMP: 通过突变表型推断
25656649 GOA
involved in positive regulation of autophagy IDA
IDA: 通过直接分析推断
23184933 GOA
involved in positive regulation of cell migration IDA
IDA: 通过直接分析推断
25656649 GOA
involved in positive regulation of cell population proliferation IDA
IDA: 通过直接分析推断
25656649 GOA
involved in positive regulation of cell population proliferation IGI
IGI: 通过遗传相互作用推断
25656649 GOA
involved in positive regulation of endothelial cell apoptotic process IDA
IDA: 通过直接分析推断
25280941 GOA
involved in positive regulation of immunoglobulin production IDA
IDA: 通过直接分析推断
11460154 GOA
NOT involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: 通过直接分析推断
26315405 GOA
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: 通过直接分析推断
26315405 GOA
involved in positive regulation of plasma cell differentiation IDA
IDA: 通过直接分析推断
11460154 GOA
involved in positive regulation of protein acetylation IDA
IDA: 通过直接分析推断
25280941 GOA
involved in positive regulation of protein import into nucleus IDA
IDA: 通过直接分析推断
25190803 GOA
involved in positive regulation of protein phosphorylation IDA
IDA: 通过直接分析推断
25190803 GOA
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
8657566 GOA
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
1903538 GOA
NOT involved in positive regulation of vascular associated smooth muscle cell migration IDA
IDA: 通过直接分析推断
26315405 GOA
involved in positive regulation of vascular associated smooth muscle cell migration IDA
IDA: 通过直接分析推断
26315405 GOA
NOT involved in positive regulation of vascular associated smooth muscle cell proliferation IDA
IDA: 通过直接分析推断
26315405 GOA
involved in positive regulation of vascular associated smooth muscle cell proliferation IDA
IDA: 通过直接分析推断
26315405 GOA
involved in positive regulation of vascular wound healing IDA
IDA: 通过直接分析推断
25656649 GOA
involved in protein destabilization IDA
IDA: 通过直接分析推断
16461360 GOA
involved in protein destabilization IMP
IMP: 通过突变表型推断
25280941 GOA
involved in regulation of cell growth IDA
IDA: 通过直接分析推断
23529610 GOA
involved in regulation of protein stability IDA
IDA: 通过直接分析推断
25190803 GOA
involved in response to endoplasmic reticulum stress IDA
IDA: 通过直接分析推断
11779464 GOA
involved in vascular endothelial growth factor receptor signaling pathway IDA
IDA: 通过直接分析推断
23529610 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of RNA polymerase II transcription regulator complex IPI
IPI: 通过物理相互作用推断
23661758 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
16461360 GOA
located in cytosol IDA
IDA: 通过直接分析推断
20348923 GOA
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
23529610 GOA
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
25239945 GOA
is active in nucleus IDA
IDA: 通过直接分析推断
16461360 GOA
located in nucleus IDA
IDA: 通过直接分析推断
16461360 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

XBP1 蛋白结构

bZIP_2

bZIP_2: Basic region leucine zipper (69 - 120)

  • 0
  • 100
  • 200
  • 261 a.a.
蛋白主名 其他名称

X-box-binding protein 1

tax-responsive element-binding protein 5

XBP1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra XBP1 P17861 UBE2V1 Homo sapiens Q13404
Validated Y2H
32296183
Intra XBP1 P17861 ATF6B Homo sapiens Q99941
FRET
23661758
Intra XBP1 P17861 CREBZF Homo sapiens Q9NS37
Peptide Array
20102225
Intra XBP1 P17861 CREBZF Homo sapiens Q9NS37
FRET
23661758
Intra XBP1 P17861 XBP1 Homo sapiens P17861
Peptide Array
20102225
Intra XBP1 P17861 XBP1 Homo sapiens P17861
FRET
23661758
Intra XBP1 P17861 XBP1 Homo sapiens P17861
Peptide Array
12805554
Intra XBP1 P17861 ATF6 Homo sapiens P18850
FRET
23661758
Intra XBP1 P17861 ATF6 Homo sapiens P18850
Peptide Array
20102225
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Major Affective Disorder 7

MAFD7

Bipolar Affective Disorder

Major Affective Disorder-7, Susceptibility To

Major Affective Disorder-7

Manic Depressive Illness

Manic-Depressive Psychosis

Major Affective Disorder 7, Susceptibility To

Bipolar Disorder

Major Affective Disorder 2

Major Affective Disorder 1

Fatty Liver Disease

Alcoholic Fatty Liver

Fatty Liver

Fatty Liver, Alcoholic

Fatty Change Of Liver

Hepatic Lipidosis

Steatosis Of Liver

Fatty Liver Alcoholic

Steatohepatitis

Etoh Fatty Liver

Etoh Fatty Liver Metamorphosis

Fatty Etoh Liver Necrosis

Liver Disease

Liver Failure

Liver Diseases

Abnormality Of The Liver

Liver Dysfunction

Disorder Of Liver

Hepatic Disorder

Hepatic Disease

Disease Of Bilirubin Metabolism

Disorder Of Bilirubin Metabolism

Liver Decompensation

Liver Function Failure

Hepatic Failure Nos

Liver Failure Nos

End Stage Liver Disease

Decompensated Liver Failure

Decompensation Of Liver Function

Hepatic Decompensation

Hepatic Insufficiency

Liver Cell Necrosis With Hepatic Failure

Liver Insufficiency

Decompensated Liver Disease

End Stage Liver Failure

Liver Necrosis With Hepatic Failure

Bipolar Disorder

Bipolar Depression

Manic Disorder

Depression, Bipolar

Bipolar Disorder Manic Phase

Depressive-Manic Psych.

Manic Bipolar Affective Disorder

Manic Bipolar I Disorder

Manic Depression

Manic Depressive Disorder

Mixed Bipolar Disorder

Bipolar Affective Disorder

Bipolar Affective Psychosis

Bipolar Spectrum Disorder

Manic Depressive Illness

Depression Bipolar

Bipolar Disorder, Mixed

Major Affective Disorder

Major Affective Disorder 1

Major Affective Disorder 2

B-Cell Lymphoma

Lymphoma, B-Cell

B-Cell Lymphomas

B-Cell Lymphocytic Neoplasm

Lymphoma B-Cell

B-Cell Lymphoma Nos

Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation

Epiphyseal Dysplasia, Multiple, With Early-Onset Diabetes Mellitus

Wolcott-Rallison Syndrome

Med-Iddm Syndrome

Iddm-Med Syndrome

Wolcott Rallison Syndrome

WRS

Epiphyseal Dysplasia Multiple With Early-Onset Diabetes Mellitus

Early-Onset Diabetes Mellitus With Multiple Epiphyseal Dysplasia

Multiple Epiphyseal Dysplasia With Early-Onset Diabetes Mellitus

Ileocolitis

Iieocolitis

Burkitt Lymphoma

Burkitt'S Lymphoma

BL

Burkitt Lymphoma, Somatic

Burkitt Lymphoma/Leukaemia

Burkitt'S Tumor

Burkitt'S Tumor Or Lymphoma

Malignant Lymphoma, Burkitt'S Type

Small Non-Cleaved Cell Lymphoma, Burkitt'S Type

Small Non-Cleaved Cell Lymphoma

Burkitt Tumor

Burkitts Lymphoma

Lymphoma, Small Noncleaved-Cell

Burkitt Tumour

Diffuse Small Noncleaved Malignant Burkitt Lymphoma

Malignant Burkitt Lymphoma

“Burkitt-Like” Lymphoma

Undifferentiated Burkitt Lymphoma

Small Noncleaved Cell Burkitt Lymphoma

Wolfram Syndrome 1

WFS1

Didmoad

Wfs

Diabetes Mellitus And Insipidus With Optic Atrophy And Deafness

Diabetes Insipidus And Mellitus With Optic Atrophy And Deafness

Diabetes Insipidus And Mellitus With Optic Atrophy And Deafness Syndrome

Wolfram Syndrome

Congenital Hypothyroidism

Cretinism

Neonatal Hypothyroidism

Ch

Cht

Congenital Myxedema

Myxedema, Congenital

Endemic Cretinism

Congenital Iodine-Deficiency Syndrome

Fetal Iodine Deficiency Syndrome

Congenital Iodine-Deficiency Hypothyroidism Nos

Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory

Myeloma, Multiple

Multiple Myeloma

Plasma Cell Myeloma

Kahler Disease

Myelomatosis

Medullary Plasmacytoma

Multiple Myeloma, Resistance To

Myeloma

Plasma Cell Dyscrasia

Kahler'S Disease

Multiple Myeloma, Susceptibility To

Myeloma - Multiple

Kahler-Bozzolo Disease

Plasma Cell Myelomas

MM

Plasma Cell Neoplasm

Primary Systemic Amyloidosis

Primary Amyloidosis

Immunoglobulin Deposition Disease

Plasmacytic Myeloma

Multiple Myelomata

Multiple Myeloma Nos

Multiple Myeloma Without Mention Of Remission

Monostotic Plasma Cell Myeloma

Mm - [Multiple Myeloma]

Wolfram Syndrome

Didmoad Syndrome

Didmoad

Diabetes Insipidus And Mellitus With Optic Atrophy And Deafness

Wfs

Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, And Deafness

Didmoadud

Diabetes Insipidus-Diabetes Mellitus-Optic Atrophy-Deafness Syndrome

Diabetes Insipidus-Diabetes Mellitus-Optic Atrophy-Hearing Loss Syndrome

Common Variable Immunodeficiency

Cvid

Common Variable Agammaglobulinemia

Common Variable Immune Deficiency

Acquired Hypogammaglobulinemia

Hypogamma-Globulinemia, Acquired

Idiopathic Immunoglobulin Deficiency

Primary Antibody Deficiency

Primary Hypogammaglobulinemia

Acquired Agammaglobulinemia

Sporadic Hypogammaglobulinemia

Common Variable Hypogamma-Globulinemia

Immunoglobulin Deficiency, Late-Onset

Common Variable Hypogammaglobulinemia

Immunodeficiency, Common Variable

Retinal Degeneration

Degeneration Of Retina

Cardiomyopathy, Familial Hypertrophic, 16

Hypertrophic Cardiomyopathy 16

CMH16

Cardiomyopathy, Hypertrophic, 16

Cardiomyopathy Familial Hypertrophic 16

Cardiomyopathy, Familial Hypertrophic 16

Cardiomyopathy, Hypertrophic, Familial, Type 16

Cardiomyopathy, Familial Hypertrophic, 18

Hypertrophic Cardiomyopathy 18

CMH18

Cardiomyopathy, Hypertrophic, 18

Cardiomyopathy Familial Hypertrophic 18

Cardiomyopathy, Familial Hypertrophic 18

Cardiomyopathy, Hypertrophic, Familial, Type 18

Cardiomyopathy, Familial Hypertrophic, 17

Hypertrophic Cardiomyopathy 17

CMH17

Cardiomyopathy, Hypertrophic, 17

Cardiomyopathy Familial Hypertrophic 17

Cardiomyopathy, Familial Hypertrophic 17

Cardiomyopathy, Hypertrophic, Familial, Type 17

Cystic Fibrosis

Mucoviscidosis

CF

Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis

Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis

Cystic Fibrosis Lung Disease, Modifier Of

Cystic Fibrosis Of Pancreas

Fibrocystic Disease Of Pancreas

Cf - [Cystic Fibrosis]

Cystic Fibrosis Nos

Fibrocystic Disease

Fibrocystic Disease Of The Pancreas

Mucoviscidosis Of Pancreas

Nonproliferative Fibrocystic Disease

Pancreatic Cystic Fibrosis

Schizophrenia

SCZD

Schizophrenia With Or Without An Affective Disorder

Schizophrenia 12

Schizophrenia, Susceptibility To

Schizophrenia-1

Dementia Praecox

Schizophrenia 1

Amyotrophic Lateral Sclerosis 1

Amyotrophic Lateral Sclerosis

ALS

Lou Gehrig Disease

Amyotrophic Lateral Sclerosis Type 1

Charcot Disease

ALS1

Amyotrophic Lateral Sclerosis, Susceptibility To

Fals

Lou Gehrig'S Disease

Mnd

Motor Neuron Disease

Familial Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis 1, Familial

Amyotrophic Lateral Sclerosis 1, Autosomal Dominant

Motor Neuron Disease, Bulbar

Motor Neurone Disease

Amyotrophic Lateral Sclerosis With Dementia

Dementia With Amyotrophic Lateral Sclerosis

Motor Neuron Disease, Amyotrophic Lateral Sclerosis

Sclerosis, Lateral, Amyotrophic

Sclerosis, Lateral, Amyotrophic, Type 1

Amyotrophic Sclerosis

Als - [Amyotrophic Lateral Sclerosis]

Wasting Palsy

Amyotrophic Paralysis

Amyotrophy Lateral Sclerosis

Wasting Paralysis

Spinal Progressive Amyotrophy

Progressive Atrophic Paralysis

Diabetes Mellitus

Diabetes

T-Cell Acute Lymphoblastic Leukemia

T-Cell Leukemia

Acute T Cell Leukemia

Precursor T Lymphoblastic Leukemia

Precursor T-Lymphoblastic Lymphoma/Leukemia

T Acute Lymphoblastic Leukemia

T-Cell Acute Lymphocytic Leukaemia

T-Cell Lymphoblastic Leukemia/Lymphoma

Leukemia T-Cell

Leukemia, T-Cell

Leukemia, Acute, Lymphoblastic, T-Cell

Leukemia, T-Cell Acute Lymphoblastic

Leukemia, Acute T-Cell

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Precursor T-Cell Lymphoblastic Lymphoma

Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma

Type 2 Diabetes Mellitus

Insulin Resistance

NIDDM

Type 2 Diabetes

Diabetes Mellitus, Non-Insulin-Dependent

T2D

Noninsulin-Dependent Diabetes Mellitus

Diabetes Mellitus, Type Ii

Maturity-Onset Diabetes

Insulin Resistance, Severe, Digenic

Diabetes Mellitus, Type 2

Diabetes Mellitus, Noninsulin-Dependent

Diabetes Mellitus, Noninsulin-Dependent, Association With

Diabetes Mellitus, Noninsulin-Dependent, Late Onset

Hypertension, Insulin Resistance-Related, Susceptibility To

Insulin Resistance, Susceptibility To

Non-Insulin-Dependent Diabetes Mellitus

Type Ii Diabetes Mellitus

Adult-Onset Diabetes Mellitus

Maturity-Onset Diabetes Mellitus

Diabetes Mellitus Type 2

Type Ii Diabetes

Type 2 Diabetes Mellitus, Susceptibility To

Diabetes, Type 2

Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To

Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To

Diabetes Mellitus, Type 2, Susceptibility To

Diabetes Mellitus, Noninsulin-Dependent, 2

Diabetes Mellitus, Type Ii, Susceptibility To

Hypertension, Insulin Resistance-Related

Adult-Onset Diabetes

Aodm

Diabetes Mellitus, Adult-Onset

Diabetes Mellitus Type Ii

Diabetes Mellitus Type 2, Susceptibility To

Diabetes, Type Ii, Susceptibility To

Diabetes Type 2

Diabetes Mellitus

Adult Onset Diabetes

Maturity Onset Diabetes

Nonketotic Diabetes

Non-Insulin Dependent Diabetes Mellitus

T2dm - [Type 2 Diabetes Mellitus]

Niddm - [Non Insulin Dependent Diabetes Mellitus]

Dm2

Dm Type Ii

Diabetic Type 2

Insulin Requiring Type 2 Diabetes

Noninsulin Dependent Diabetes

Non-Insulin-Dependent Diabetes Mellitus Without Complications

Diabetes Due To Insulin Secretory Defect

Diabetes Mellitus Due To Insulin Secretory Defect

Non-Insulin-Dependent Diabetes Of The Young

Senile Diabetes

Nonketotic Hyperglycaemia

Stable Diabetes

Nervous System Disease

Abnormality Of The Nervous System

Nervous System Diseases

Nervous System Disorder

Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

Non-Syndromic Retinitis Pigmentosa

Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus XBP1 MGD MGI:98970
Bos taurus XBP1 VGNC VGNC:53930
Rattus norvegicus XBP1 RGD RGD:1303073
Felis catus XBP1 VGNC VGNC:67102
Macaca mulatta XBP1 VGNC VGNC:78806