2. Gene
  3. SAP130 - Sin3A associated protein 130 Gene

SAP130 - Sin3A associated protein 130 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：Sin3A 相关蛋白 130

种属: Homo sapiens

基因 ID: 79595 | 基因类型: protein coding

关于 SAP130

Cytogenetic location: 2q14.3 Genomic coordinates (GRCh38): 2:127,941,222-128,028,059 (from NCBI)

This gene has 6 transcripts (splice variants) and 228 orthologues. Broad expression in testis (RPKM 33.8), bone marrow (RPKM 7.4) and 24 other tissues.

功能概要

SAP130 是组蛋白脱乙酰酶 (参见 HDAC1；MIM 601241) 依赖性 SIN3A (MIM 607776) 辅抑制复合物的一个亚基 (Fleischer 等人，2003 [PubMed 12724404]) 。[OMIM 提供，2008 年 3 月]

SAP130 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).[supplied by OMIM, Mar 2008]

SAP130 基因产物(7)

mRNA Protein Name
NM_001145928.2 NP_001139400.1 histone deacetylase complex subunit SAP130 isoform a
NM_001330299.2 NP_001317228.1 histone deacetylase complex subunit SAP130 isoform c
NM_001330300.2 NP_001317229.1 histone deacetylase complex subunit SAP130 isoform d
NM_001330301.2 NP_001317230.1 histone deacetylase complex subunit SAP130 isoform e
NM_001330302.2 NP_001317231.1 histone deacetylase complex subunit SAP130 isoform f
NM_001330303.2 NP_001317232.1 histone deacetylase complex subunit SAP130 isoform g
NM_024545.4 NP_078821.2 histone deacetylase complex subunit SAP130 isoform b
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
22783022 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

histone deacetylase complex subunit SAP130

130 kDa Sin3-associated polypeptide

关联疾病

疾病名称 别名
Pleuropneumonia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12437 SAP130 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris SAP130 VGNC VGNC:45858
Mus musculus SAP130 MGD MGI:1919782
Bos taurus SAP130 VGNC VGNC:34280
Macaca mulatta SAP130 VGNC VGNC:77127
Felis catus SAP130 VGNC VGNC:64868
Rattus norvegicus SAP130 RGD RGD:1311657
Others SAP130 NCBI
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